##gff-version 3
Q17967	UniProtKB	Signal peptide	1	20	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q17967	UniProtKB	Chain	21	485	.	.	.	ID=PRO_0000034203;Note=Protein disulfide-isomerase 1	
Q17967	UniProtKB	Domain	21	130	.	.	.	Note=Thioredoxin 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00691	
Q17967	UniProtKB	Domain	342	470	.	.	.	Note=Thioredoxin 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00691	
Q17967	UniProtKB	Motif	482	485	.	.	.	Note=Prevents secretion from ER;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU10138	
Q17967	UniProtKB	Active site	393	393	.	.	.	Note=Nucleophile;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q17967	UniProtKB	Active site	396	396	.	.	.	Note=Nucleophile;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q17967	UniProtKB	Site	394	394	.	.	.	Note=Contributes to redox potential value;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q17967	UniProtKB	Site	395	395	.	.	.	Note=Contributes to redox potential value;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q17967	UniProtKB	Site	456	456	.	.	.	Note=Lowers pKa of C-terminal Cys of second active site;Ontology_term=ECO:0000250;evidence=ECO:0000250	
Q17967	UniProtKB	Disulfide bond	52	55	.	.	.	Note=Redox-active;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00691	
Q17967	UniProtKB	Disulfide bond	393	396	.	.	.	Note=Redox-active;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00691