Q178U8 (Q178U8_AEDAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Fructose-bisphosphate aldolase RuleBase RU003994
EC=4.1.2.13 RuleBase RU003994

Gene names

ORF Names:

AAEL005766, AaeL_AAEL005766 EMBL EAT42703.1

Organism

Aedes aegypti (Yellowfever mosquito) (Culex aegypti)

Taxonomic identifier

7159 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicoidea › Culicidae › Culicinae › Aedini › Aedes › Stegomyia

Protein attributes

Sequence length	364 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. RuleBase RU003994
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4. RuleBase RU004257
Sequence similarities	Belongs to the class I fructose-bisphosphate aldolase family. RuleBase RU003994

Ontologies

Keywords
Biological process	Glycolysis RuleBase RU003994
Molecular function	Lyase RuleBase RU003994
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	fructose-bisphosphate aldolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q178U8 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: 34CC159D22AD875D	FASTA	364	39,484
	10 20 30 40 50 60 MTTYFNYPPK DVQEELARIA KAIVAPGKGI LAADESTATC GKRFADIGVE NNEDNRRQYR 70 80 90 100 110 120 QLLFTADDRL QENISGVILF HETLYQKADD GTPLAAMLKK KGILAGIKVD KGVVDLMGSE 130 140 150 160 170 180 GECTTQGLDD LGARCAQYKK DGCDFAKWRC VLKIGKNTPS YQAILENANV LARYASVCQS 190 200 210 220 230 240 QRIVPIVEPE ILPDGDHDLE RCQKVTETVL AAVYKALNDH HVFLEGTLLK PNMVTAGQSC 250 260 270 280 290 300 AKKPSAQEIA LATVLALRRT VPAAVPGVTF LSGGQSEEEA SVNLNAINQV PLLRPWALTF 310 320 330 340 350 360 SYGRALQASV LRAWGGKKEN LKAAQDELIK RAKANGLACQ AKYVAGSIPS YAANASLFVK SHAY

References

[1]

"Genome sequence of Aedes aegypti, a major arbovirus vector." Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J., Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P. , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W. Science 316:1718-1723(2007) [PubMed: 17510324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LVPib12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH477359 Genomic DNA. Translation: EAT42703.1.
RefSeq	XP_001651423.1. XM_001651373.1.
UniGene	Aae.11008.
3D structure databases
ProteinModelPortal	Q178U8.
SMR	Q178U8. Positions 2-364.
ModBase	Search...
Protein-protein interaction databases
STRING	Q178U8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AAEL005766-RB; AAEL005766-PB; AAEL005766.
GeneID	5567031.
KEGG	aag:AaeL_AAEL005766.
VectorBase	AAEL005766. Aedes aegypti.
Phylogenomic databases
eggNOG	inNOG04727.
GeneTree	EMGT00050000013563.
OMA	REMLFRS.
OrthoDB	EOG4WPZJ4.
PhylomeDB	Q178U8.
Family and domain databases
InterPro	IPR000741. Aldolase_I. IPR013785. Aldolase_TIM. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01623.
PANTHER	PTHR11627. Aldolase_I. 1 hit.
Pfam	PF00274. Glycolytic. 1 hit. [Graphical view]
PROSITE	PS00158. ALDOLASE_CLASS_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q178U8_AEDAE

Accession

Primary (citable) accession number: Q178U8

Entry history

Integrated into UniProtKB/TrEMBL:	July 25, 2006
Last sequence update:	July 25, 2006
Last modified:	January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)