Reviewed, UniProtKB/Swiss-Prot Q17848 (I5P1_CAEEL)

Names and origin

Protein names

Recommended name:
    Probable type I inositol-1,4,5-trisphosphate 5-phosphatase
      Short name=5PTase
    EC=3.1.3.56

Gene names

Name:	ipp-5
ORF Names:	C09B8.1

Organism

Caenorhabditis elegans [Complete proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	409 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate. 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
Sequence similarities	Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type I family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	positive regulation of growth rate Inferred from mutant phenotype. Source: WormBase
Molecular function	inositol-polyphosphate 5-phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 409	409	Probable type I inositol-1,4,5-trisphosphate 5-phosphatase		PRO_0000209720

Sequences

	Sequence		Length	Mass (Da)
	Q17848-1 [UniParc]. Last modified October 25, 2004. Version 2. Checksum: 1A3CC044F00F9443	FASTA	409	47,602
	10 20 30 40 50 60 MVQYLLITAN VGSLFEPDAR LHTSWIKTVA DQVESVDPSF FVIHLQETGG KKFTECSQQV 70 80 90 100 110 120 PIIINRLSTA LPKFDLLRAY VDIDYEAIEY TALGALCFIK RSLWSNVSQF NFHTKKYEQL 130 140 150 160 170 180 TSPKEVVTHG LENYPYVVKH KFPKDFWPSI KWGRKGYMQT RWKIENKVFD FVNAHLFHDE 190 200 210 220 230 240 SNLALIHENP QLYSQNRKRA LDFVLAELSS KENGCTPLLF VFGDLNFRLD SRSFLNRLTE 250 260 270 280 290 300 RTAQHPVADQ EQMGSLADGL QASAANLQVI THPSENLRRT VSAIEFRRES DSDDSQNSCV 310 320 330 340 350 360 LRIEKKKFDY FNHKKLLDDW RSYRDDDKET ENFQSMFEMH INFPPTYPWS EDPENSETLM 370 380 390 400 KTRAPAWCDR VLMNKNAYSL VEEGEPQYRS FGMETCTGDH KPVMLTFNI

References

[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed: 9851916] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
[2]	"Expression map of C. elegans genome." Kohara Y., Motohashi T., Tabara H., Watanabe H., Sugimoto A., Sano M., Miyata A., Nishigaki A., Bui Y.K., Sternberg P.W. Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-400.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U29612 Genomic DNA. Translation: AAA68800.2. AF411588 mRNA. Translation: AAL72637.1.
PIR	T15465.
RefSeq	NP_509008.2.
UniGene	Cel.9138
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	C09B8.1. Caenorhabditis elegans. [Contig view]
GeneID	180871.
KEGG	cel:C09B8.1.
NMPDR	fig|6239.3.peg.23428.
Organism-specific databases
WormBase	WBGene00002146. ipp-5.
WormPep	C09B8.1. CE30857. [WorfDB]
Phylogenomic databases
OMA	Q17848. ITANVGS.
Enzyme and pathway databases
BRENDA	3.1.3.56. 672.
Gene expression databases
ArrayExpress	Q17848.
Family and domain databases
InterPro	IPR005135. Endo/exonuclease/phosphatase. IPR000300. IPPc. [Graphical view]
Pfam	PF03372. Exo_endo_phos. 1 hit. [Graphical view]
SMART	SM00128. IPPc. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	911342.

Entry information

Entry name

I5P1_CAEEL

Accession

Primary (citable) accession number: Q17848
Secondary accession number(s): Q8WRS7

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	October 25, 2004
Last modified:	May 5, 2009
This is version 52 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Caenorhabditis annotation project