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Protein

ATP-dependent RNA helicase SUV3 homolog, mitochondrial

Gene

C08F8.2

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

ATPase and DNA/RNA helicase able to unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes in the 5'-3' direction.By similarity

Catalytic activityi

ATP + H2O = ADP + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi196 – 203ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicase, Hydrolase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent RNA helicase SUV3 homolog, mitochondrial (EC:3.6.4.13)
Gene namesi
ORF Names:C08F8.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiC08F8.2a; CE19689; WBGene00007444.
C08F8.2b; CE05249; WBGene00007444.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Mitochondrion, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 45MitochondrionSequence analysisAdd BLAST45
ChainiPRO_000031055146 – 721ATP-dependent RNA helicase SUV3 homolog, mitochondrialAdd BLAST676

Proteomic databases

EPDiQ17828.
PaxDbiQ17828.
PeptideAtlasiQ17828.
PRIDEiQ17828.

Expressioni

Gene expression databases

BgeeiWBGene00007444.
ExpressionAtlasiQ17828. baseline.

Interactioni

Protein-protein interaction databases

IntActiQ17828. 1 interactor.
STRINGi6239.C08F8.2a.

Structurei

3D structure databases

ProteinModelPortaliQ17828.
SMRiQ17828.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini183 – 321Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST139
Domaini345 – 501Helicase C-terminalPROSITE-ProRule annotationAdd BLAST157

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili691 – 721Sequence analysisAdd BLAST31

Sequence similaritiesi

Belongs to the helicase family.Curated

Keywords - Domaini

Coiled coil, Transit peptide

Phylogenomic databases

eggNOGiKOG0953. Eukaryota.
ENOG410XSEY. LUCA.
GeneTreeiENSGT00390000003100.
HOGENOMiHOG000175283.
InParanoidiQ17828.
KOiK17675.
OMAiADMIQHI.
OrthoDBiEOG091G02NO.
PhylomeDBiQ17828.

Family and domain databases

InterProiView protein in InterPro
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR022192. SUV3_C.
PfamiView protein in Pfam
PF00271. Helicase_C. 1 hit.
PF12513. SUV3_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiView protein in PROSITE
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q17828-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQMRRASGVL RVLGGLTQRC STSSTPSSSR FPAMNSRRKR NSVRKTATIE
60 70 80 90 100
DIVEPRKVKH VTQTAAGMGE WIGSLDNTNI HMSLDEFMRR PMVRQLAKEN
110 120 130 140 150
GINDKLFMRS FKSFREYCTP EDLNSVDPGL LILLSDISKG TKDCEMLYPF
160 170 180 190 200
FLDHAKQVFP HLEAMDDLRI ISDLTRPHNW YPEARSVTRK IFFHAGPTNS
210 220 230 240 250
GKTYHALKRF GEAKSAVFCG PLKLLAAEVF HRTNELGIPC DLVTGEERRF
260 270 280 290 300
AKDNHHPSQH LSSTVEMLST QMRVEVAVID EIQMLRDEQR GWAWTRALLG
310 320 330 340 350
AAADEIHLCG EPAAIDIVKK LLEPIGETVE VRYYERKSPL AIADKAIESY
360 370 380 390 400
SNIEPGDCIV CFSKRSIFFN SKKLEENGIK PAVIYGDLPP GTKLAQAAKF
410 420 430 440 450
NDPDDECNVL VATDAIGMGL NLNIRRVIFN SCTRQTELLP TYAALQIAGR
460 470 480 490 500
AGRFGTAYAN GVATTMRKED LGTLKAILSE KIEPIANVGI APTYDQIETF
510 520 530 540 550
SFHLPQASFV RLLDLFVSVC SVSDHFFICT VYDMRELAVL IDQIPLPLKV
560 570 580 590 600
RYTFCTSPLN TEDKRTSAVF VKMARRFSTG QALTYEWLID MLEWPPKPAT
610 620 630 640 650
TLNELSLLEQ NYEILDQYMW LSMRFPDMLP DEPRVREASK HLDSMIQEGV
660 670 680 690 700
ESFMSLLSVG ATESKAAGSS KSSEGKRENP SKSEREKPNK RSSILEALLK
710 720
RADISEDDLE QLREELNKNK K
Length:721
Mass (Da):81,269
Last modified:May 1, 1999 - v2
Checksum:i4D86730DA4A44E9F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z73103 Genomic DNA. Translation: CAA97429.1.
Z73103 Genomic DNA. Translation: CAJ43433.1.
PIRiT19103.
RefSeqiNP_001040911.1. NM_001047446.4.
NP_001040912.1. NM_001047447.2.
UniGeneiCel.20693.

Genome annotation databases

EnsemblMetazoaiC08F8.2a; C08F8.2a; WBGene00007444.
GeneIDi178022.
KEGGicel:CELE_C08F8.2.
UCSCiC08F8.2a. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiSUV3_CAEEL
AccessioniPrimary (citable) accession number: Q17828
Secondary accession number(s): Q2XN00
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: May 1, 1999
Last modified: April 12, 2017
This is version 118 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Caution

It is uncertain whether Met-1 or Met-3 is the initiator.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families