Q177S6 (Q177S6_AEDAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydroorotate dehydrogenase EMBL EAT42442.1

Gene names

ORF Names:

AAEL006033, AaeL_AAEL006033 EMBL EAT42442.1

Organism

Aedes aegypti (Yellowfever mosquito) (Culex aegypti)

Taxonomic identifier

7159 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicoidea › Culicidae › Culicinae › Aedini › Aedes › Stegomyia

Protein attributes

Sequence length	395 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	'de novo' pyrimidine base biosynthetic process Inferred from electronic annotation. Source: InterPro UMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	membrane Inferred from electronic annotation. Source: InterPro
Molecular function	dihydroorotate oxidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	210	1	Nucleophile By similarity PIRSR PIRSR000164-1

Sequences

	Sequence		Length	Mass (Da)
	Q177S6 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: 78B06584A9D9CCEF	FASTA	395	43,438
	10 20 30 40 50 60 MNPCRASTPN KFRSLVKVTS LGAVTFSAIC LYKGNEKFYE SIFMPIVRLI PPETAHQLAV 70 80 90 100 110 120 FGIKLALVRP SFQDPETLRT RFLGMTVSNP VGIAAGFDKH GEAVAGLQRI GFGFVEIGSV 130 140 150 160 170 180 TPKPQPGNQR PRVFRLNEDK AIVNRYGFNS DGHDVVYERL KKMREENPNR VMLGVNLGRN 190 200 210 220 230 240 KHSPDAYNDY IQGIKKFSCL ADYLVINISS PNTPGLRAMQ NKTTLQVLLS EVLKARSALP 250 260 270 280 290 300 PEEQRPILVK FAPDLADEDV QEIVTVVMQK EFAVDGVIVS NTTIDRPASL KSINAGQIGG 310 320 330 340 350 360 LSGAPLCQRS TQLIAKVYKW TEGKIPIIGV GGIFSGQDAY DKIQAGASVV QLYTAFIFHG 370 380 390 PPVVTRVKQE LDAILRKNGY KSVEEAVGKG YEKFL

References

[1]

"Genome sequence of Aedes aegypti, a major arbovirus vector." Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J., Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P. , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W. Science 316:1718-1723(2007) [PubMed: 17510324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LVPib12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH477371 Genomic DNA. Translation: EAT42442.1.
RefSeq	XP_001657386.1. XM_001657336.1.
UniGene	Aae.11294.
3D structure databases
ProteinModelPortal	Q177S6.
SMR	Q177S6. Positions 33-393.
ModBase	Search...
Protein-protein interaction databases
STRING	Q177S6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AAEL006033-RA; AAEL006033-PA; AAEL006033.
GeneID	5567371.
KEGG	aag:AaeL_AAEL006033.
VectorBase	AAEL006033. Aedes aegypti.
Phylogenomic databases
eggNOG	inNOG06457.
GeneTree	EMGT00050000010553.
OMA	AALNRMG.
OrthoDB	EOG43BK4M.
PhylomeDB	Q177S6.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR012135. Dihydroorotate_DH_1_2. IPR005719. Dihydroorotate_DH_2. IPR001295. Dihydroorotate_DH_CS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00254.
Pfam	PF01180. DHO_dh. 1 hit. [Graphical view]
PIRSF	PIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMs	TIGR01036. PyrD_sub2. 1 hit.
PROSITE	PS00911. DHODEHASE_1. 1 hit. PS00912. DHODEHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q177S6_AEDAE

Accession

Primary (citable) accession number: Q177S6

Entry history

Integrated into UniProtKB/TrEMBL:	July 25, 2006
Last sequence update:	July 25, 2006
Last modified:	January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)