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Q17551

- RPM1_CAEEL

UniProt

Q17551 - RPM1_CAEEL

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Protein

E3 ubiquitin-protein ligase rpm-1

Gene

rpm-1

Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, including dlk-1. Negatively regulates a p38 MAP kinase pathway composed of dlk-1, mkk-4, and pmk-3 that functions presynaptically to regulate synaptic architecture. Has a role during synaptogenesis; regulates neuronal morphology, specifically presynaptic differentiation. May regulate the spatial arrangement of presynaptic terminals or restrict their development.3 Publications

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri3331 – 337949B box-typePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri3517 – 356852RING-type; atypicalPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. mitogen-activated protein kinase kinase kinase binding Source: WormBase
  3. ubiquitin-protein transferase activity Source: WormBase
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. body morphogenesis Source: WormBase
  2. locomotion Source: WormBase
  3. negative regulation of MAPK cascade Source: WormBase
  4. oviposition Source: WormBase
  5. regulation of protein stability Source: WormBase
  6. regulation of synapse organization Source: WormBase
  7. regulation of transcription, DNA-templated Source: UniProtKB-KW
  8. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Transcription, Transcription regulation, Ubl conjugation pathway

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

SignaLinkiQ17551.
UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Recommended name:
E3 ubiquitin-protein ligase rpm-1 (EC:6.3.2.-)
Alternative name(s):
Pam/highwire/rpm-1 protein
Regulator of presynaptic morphology protein 1
Synapse defective protein 3
Gene namesi
Name:rpm-1
Synonyms:syd-31 Publication
ORF Names:C01B7.6
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome V

Organism-specific databases

WormBaseiC01B7.6; CE06730; WBGene00004457; rpm-1.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. axon Source: WormBase
  2. neuromuscular junction Source: WormBase
  3. nucleus Source: UniProtKB-KW
  4. presynaptic periactive zone Source: WormBase
  5. synapse Source: WormBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

In mutants, mechanosensory neurons fail to accumulate tagged vesicles, retract synaptic branches and ectopically extend axons. Some motor neurons branch and overgrow, others show altered synaptic organization.1 Publication

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi3597 – 35971R → C in ky346; total number of the synaptic vesicle GFP puncta is reduced. 1 Publication
Mutagenesisi3675 – 36751C → Y in ju44; total number of the synaptic vesicle GFP puncta is reduced. 1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 37663766E3 ubiquitin-protein ligase rpm-1PRO_0000055970Add
BLAST

Proteomic databases

PaxDbiQ17551.
PRIDEiQ17551.

Expressioni

Tissue specificityi

Expression is seen in the pharynx, coelomocytes and distal tip cell. Most abundant expression is in axons of the nerve ring neuropil. Expression is not seen in body wall muscle, hypodermis or intestine.2 Publications

Developmental stagei

First expressed in comma stage embryos and persists through to adulthood.1 Publication

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
Rae1Q3SWS82EBI-6920110,EBI-6920222From a different organism.

Protein-protein interaction databases

IntActiQ17551. 2 interactions.
STRINGi6239.C01B7.6.

Structurei

3D structure databases

ProteinModelPortaliQ17551.
SMRiQ17551. Positions 615-904, 1049-1205, 1503-1654, 2059-2094, 3512-3590.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati631 – 68252RCC1 1Sequence AnalysisAdd
BLAST
Repeati725 – 78460RCC1 2Sequence AnalysisAdd
BLAST
Repeati785 – 83652RCC1 3Sequence AnalysisAdd
BLAST
Repeati838 – 89255RCC1 4Sequence AnalysisAdd
BLAST
Domaini2870 – 3046177DOCPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1056 – 1205150PHR domain 1By similarityAdd
BLAST
Regioni1503 – 1655153PHR domain 2By similarityAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi683 – 72543Cys-richSequence AnalysisAdd
BLAST
Compositional biasi2508 – 253831Gly-richSequence AnalysisAdd
BLAST

Domaini

The PHR domains are compact beta-sandwich folds composed of 11 antiparallel strands and decorated with conserved apical loops. They are likely to play a structural role and mediate interactions with substrates or partners (By similarity).By similarity

Sequence similaritiesi

Belongs to the highwire family.Curated
Contains 1 B box-type zinc finger.PROSITE-ProRule annotation
Contains 1 DOC domain.PROSITE-ProRule annotation
Contains 4 RCC1 repeats.PROSITE-ProRule annotation
Contains 1 RING-type zinc finger.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri3331 – 337949B box-typePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri3517 – 356852RING-type; atypicalPROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiNOG240798.
GeneTreeiENSGT00390000011403.
HOGENOMiHOG000016145.
InParanoidiQ17551.
KOiK10693.
OMAiLPMIFNS.
OrthoDBiEOG75B84C.
PhylomeDBiQ17551.

Family and domain databases

Gene3Di2.130.10.30. 1 hit.
2.60.120.260. 1 hit.
3.30.40.10. 1 hit.
InterProiIPR004939. APC_su10/DOC_dom.
IPR008979. Galactose-bd-like.
IPR027047. Highwire/Pam/Rpm-1.
IPR012983. PHR.
IPR009091. RCC1/BLIP-II.
IPR000408. Reg_chr_condens.
IPR000315. Znf_B-box.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PANTHERiPTHR12846:SF17. PTHR12846:SF17. 1 hit.
PfamiPF08005. PHR. 2 hits.
PF00415. RCC1. 1 hit.
PF00643. zf-B_box. 1 hit.
PF13639. zf-RING_2. 1 hit.
[Graphical view]
SMARTiSM00336. BBOX. 1 hit.
SM00184. RING. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF50985. SSF50985. 2 hits.
PROSITEiPS51284. DOC. 1 hit.
PS00626. RCC1_2. 1 hit.
PS50012. RCC1_3. 1 hit.
PS50119. ZF_BBOX. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q17551-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSFFLREIDG ERVCSTSTET SIPEDRKSAR RLRKLLYKCA ENTCKPDILR
60 70 80 90 100
VPAHCGKLDK EEEKSKTPLD QQQQINFHDI LNSKFVVGPP SPFALVAIAK
110 120 130 140 150
SILARFGNPE EVSEKEDGSE EEAGTSGADE EGKQYKNTDQ LVGASLTCIF
160 170 180 190 200
EVLEQLSRRD AELCVQALES LLSLIQSMPI DCLQSENRLS MSAMMHVLKT
210 220 230 240 250
LREDACPSVS SKATSCLVAL SVACGEPEHL GSTIRSLICM KKNIRMSADS
260 270 280 290 300
TYDMIQMPEN LRKLLLKVRR KALGGDNTAN SPPNWAMVDV HEHSVASSFS
310 320 330 340 350
LPSLPDSSPS SDTPDDDNRI HSTMACDGTF LYILNYVGLY KLGTGLNETI
360 370 380 390 400
SGKLYAANQS LQSSKNVQMY LCNGSLYLRR NYSSCISVID TDSLLDIGEV
410 420 430 440 450
ILPPSCVQHA LFTDGTYFYS ATLIANSTLS TIQLNDSFSP SNEPSSRRSH
460 470 480 490 500
RLTDVKFTIQ GDLQVPHQLP EFLPANLHPQ TVDLHFTREM AFIQARSGKV
510 520 530 540 550
YYAGNGTRFG LFETGNNWME LCLPEPIVQI SVGIDTIMFR SGAGHGWIAS
560 570 580 590 600
VDDKKRNGRL RRLVPSNRRK IVHVCASGHV YGYVSENGKI FMGGLHTMRV
610 620 630 640 650
NVSSQMLNGL DNVMISSLAL GKSHGVAVTR NGHLFTWGLN NMNQCGRVES
660 670 680 690 700
TSTTSSPRHS GRQEYQICPI GEHTWLTDTP SVCAQCGLCS ARGVACGRVP
710 720 730 740 750
RPKGTMCHCG VGESTCLRCG LCRPCGEVTE PAQPGRAQHV QFSSTAAPQR
760 770 780 790 800
STLHPSRVIL SQGPHDVKVS SVSCGNFHTV LLASDRRVFT FGSNCHGQLG
810 820 830 840 850
VGDTLSKNTP QQVILPSDTV IVQVAAGSNH TILRANDGSV FTFGAFGKGQ
860 870 880 890 900
LARPAGEKAG WNAIPEKVSG FGPGFNAFAG WIGADGDSSI IHSHTALLSS
910 920 930 940 950
DNILKAQIVA NKTNIFIFPR EVGKDYIVIR RKLNVFEHHA SDYKCWYTSW
960 970 980 990 1000
ATDPKYDMLW YYNSAEMEIK GYDIFKKSEK SVGDAFDSLT FLAGAEFAVQ
1010 1020 1030 1040 1050
VYDSPAYATS MSLGMQLLSA TFSANVINLS EFWKEKHGER EQDHEKTIMD
1060 1070 1080 1090 1100
GYSVANRFDG TGGGWGYSAN SVEAIQFKVS KEIRLVGVGL YGGRGEYISK
1110 1120 1130 1140 1150
LKLYRQIGTE ADELYVEQIT ETDETVYDCG AHETATLLFS QPIVIQPNHW
1160 1170 1180 1190 1200
HVVSAKISGP SSDCGANGKR HVECDGVTFQ FRKSAVSNNG TDVDVGQIPE
1210 1220 1230 1240 1250
LYYQIVGGSE SRDESDSNKQ LSISRDMSNL FSPAALKNVT AEGIGNLLIL
1260 1270 1280 1290 1300
LEWALQRVQI DEDTNNQVEG SAENQWSQER AGFVAILSMK LISRFVRTVY
1310 1320 1330 1340 1350
KEKGCHDEPG IDFANKLVNL HSMLLEFFFS TDMTGYENRP LIKKEEKVVE
1360 1370 1380 1390 1400
EGYTLMKCVS EAVKLFISLS HCFMGSRSLM NAHLIAVMNK GNHEALILTS
1410 1420 1430 1440 1450
AIIGSLAKIE RFAHQLLCST TTTERFPMLS SLLLKHFNCE KETLASLTSF
1460 1470 1480 1490 1500
PNILRFLYDQ TFMRNAYENT SSLAEAILVK VSRDLAIPTD DTLMGPVVHQ
1510 1520 1530 1540 1550
TSSRFRRRSA QPTWDMSDGC ADAIAFRVDS EGIKLHGFGI YLPTEPDRRN
1560 1570 1580 1590 1600
FVGEIMMLSP DSSEKWTCLL RVTAEMSSEE KEVGIVRFPE YVLLSPGVTY
1610 1620 1630 1640 1650
AVKVNMMKNT KTFCGEGGVT QVHLLNGARL FFSGCSMSQN GTTVQRGQLP
1660 1670 1680 1690 1700
YLIYSILDQS NSLQIKQETI YDTFTLLLRL MANKIGAAIT EGGALPACCQ
1710 1720 1730 1740 1750
HLMSHINPHV MVYMERFPDK ALEMMSTMEQ LIPMVSNLNG VERVFHSYDS
1760 1770 1780 1790 1800
DDSGCDTPYS GIVTTVVESQ HPYKPNTSSS MVLLFEEADY ICVRFSPDCQ
1810 1820 1830 1840 1850
TAQFDDQLTI YLKIDEHSYM PIERCYGSEW PSYPMILPGN CLMFVLDASS
1860 1870 1880 1890 1900
AVEGATSEQM FGYHVTVTGY LVGYNDSTMR LEQDLVWLSA NACRIMTQLP
1910 1920 1930 1940 1950
INPSNIEHLS TAEDDTRHLF EKHGSLLKKG LSLSHSPTLS ELCTKGQPPP
1960 1970 1980 1990 2000
AQSADLQFLR EFLSGHTSTS AGFLAKWLPT GSVVDASKCQ LSLSHDDLIV
2010 2020 2030 2040 2050
GKAVTLKLLC KDQYDREVDC PKLQVEVFAS LGHRNPSSTI HQNLHIGNLP
2060 2070 2080 2090 2100
SSLLIHQNPF QPIIVNHTRY MNIAAMPAYA NYSVEEIRLG FMIEELVKDR
2110 2120 2130 2140 2150
VPLKSSDSSL FSGTWTPTTA GKYRIECKVD GSDISHTYTV EVTERPHRAG
2160 2170 2180 2190 2200
KGTITKPSGS RRGAQMTVAR TVSIPFSSDF SGIRMRLGTT LASTSVGVIP
2210 2220 2230 2240 2250
RGALVEFIEE MDNDDGKWIR LTDETALLYG CNQGVGQVWC LAYHRPLQRE
2260 2270 2280 2290 2300
LIPLKADTDR EKAVKLRRKE IEKESNGSKH HSVSIDAKET YILSPNDVLQ
2310 2320 2330 2340 2350
VYSTPAPHSM IDGEKIIGPC DLMSSGWLAN RHGVWIKLTG VEKYVLQKND
2360 2370 2380 2390 2400
PSSETSLSFS TNGNDEEDLE RPIERKKTRL PNALTPSVAD CIRAVFAAFV
2410 2420 2430 2440 2450
WHEHLVKDLM AAAAYLRFHQ NLHNIWQSCE IPSCTNAPAA LQPIVKIWRE
2460 2470 2480 2490 2500
ICEVVETSVE QHLIMPPVSN KAMRAETVKP PSRSGGCELC DANITVPLTV
2510 2520 2530 2540 2550
HLRMAHPGCG GDCLGYGYNS NGKFTTGWSG ECGAGGRGQS PWYLLCNTCR
2560 2570 2580 2590 2600
SQYLKKTPAG HHQERTRRWR EFRFSTSASD ARPEVIIRQN AMFLLDLNSR
2610 2620 2630 2640 2650
LQTESNSSST ATSGWTINLF PTHLSTPSTM PRSQQKRLDV PPNNSVHQNS
2660 2670 2680 2690 2700
YMKLGYSSDP GPKVNVIMSP PNQGADQSAS LNRPGPSAIN EPAEVLQSPS
2710 2720 2730 2740 2750
AALRTLFSNT NPSTSALLKR PVLAFCVEHH DLKRIKSACV QSVRRAVAFS
2760 2770 2780 2790 2800
HAFRVWNWLL RMVSSEYSVS DIILQYLTTL TSYNRLAEYM FSAKKNSNIL
2810 2820 2830 2840 2850
PHPWRLCFLA GPIAADMVTQ LHAFLHTVSI ILQSAGVDGR LKSLCFKSWT
2860 2870 2880 2890 2900
LQLTAQEQDL LILTCNILGT VGGILSDTSI LDSDNRFVKE MKDITKFADI
2910 2920 2930 2940 2950
TASSRQAMVI CLTDESGETF WESGEEDKNR SRSLSVQLDE SAHGEILSLF
2960 2970 2980 2990 3000
IDNARDEGYR ISSIAFKAIL EDGRRKDLTS LTLESAYCGW LKCCIKDISH
3010 3020 3030 3040 3050
IQIQFKGPNP ASRIRQLMIL GYPAKTTGTP RLAPSTSHHL FFSDTQRDAF
3060 3070 3080 3090 3100
ALFQAISSQA FCGELSEDDT LRERVIDLLF SRVQLYPLQN YVYTQVVQAM
3110 3120 3130 3140 3150
EKEVELLCDK SKRNYSYCCG LMSLLVRICD SRGNMDSFGQ RNSVLTSITQ
3160 3170 3180 3190 3200
LLIFSPVVVQ RQCLNSLECI FASFTPSNVE VPKIIRNLLV VVGKVIQLQV
3210 3220 3230 3240 3250
RDKAAHTVVT VHLCSSVLNA PQNWRVDKSI DMDIGRQTAV LVENLCNGTY
3260 3270 3280 3290 3300
TPEWSNATKC ELANCLLSLI QMPESVSYTE TLSTGGKSKA VAVVSSKRFW
3310 3320 3330 3340 3350
TAISSLSLIK DKSWLELSER WKTVQDEEDQ EPVLLCENHD DGHTVAQVFC
3360 3370 3380 3390 3400
VDCDVALCKE CFTVMHLHKK NRNHGVKNLV QSSTQHDINI HQGCARMKFL
3410 3420 3430 3440 3450
NFLILFHGEA LNGMVEVAAD TLFPTSTSSI QPAMQSSSAF LGIHPMTCRF
3460 3470 3480 3490 3500
CGNNVPVEDQ SLDGTCTHED CVNYAKTACQ VMHTCNHFCG GIRNEEECLP
3510 3520 3530 3540 3550
CMTCKREDAA QDGDDVCVIC FTERLGAAPC IRLGCGHMFH FHCVRMILER
3560 3570 3580 3590 3600
RWNGPRIVFR FMQCPLCIQP IEHSGLQDLI EPLKTIRQEV VDKAKMRLEY
3610 3620 3630 3640 3650
DGLLTTPALT DPRSEFYNQP EEYALDRYMY VLCHKCKKAY FGGESRCQAA
3660 3670 3680 3690 3700
LDSSQFNPEE LLCGGCSDTS GVQVCPRHGV EYLEYKCRFC CSIAVYFCFG
3710 3720 3730 3740 3750
TTHFCAPCHD DFQRLMSLPK HLLPTCPVGP RSTPMEEQTC PLKMKHPPTG
3760
DEFAMGCGIC RNISTF
Length:3,766
Mass (Da):418,058
Last modified:November 1, 1996 - v1
Checksum:iEAB59E816C5BBF4D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO080217 Genomic DNA. Translation: CCD62087.1.
PIRiT29165.
RefSeqiNP_505267.1. NM_072866.3.
UniGeneiCel.2746.

Genome annotation databases

EnsemblMetazoaiC01B7.6; C01B7.6; WBGene00004457.
GeneIDi179259.
KEGGicel:CELE_C01B7.6.
UCSCiC01B7.6. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO080217 Genomic DNA. Translation: CCD62087.1 .
PIRi T29165.
RefSeqi NP_505267.1. NM_072866.3.
UniGenei Cel.2746.

3D structure databases

ProteinModelPortali Q17551.
SMRi Q17551. Positions 615-904, 1049-1205, 1503-1654, 2059-2094, 3512-3590.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q17551. 2 interactions.
STRINGi 6239.C01B7.6.

Proteomic databases

PaxDbi Q17551.
PRIDEi Q17551.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai C01B7.6 ; C01B7.6 ; WBGene00004457 .
GeneIDi 179259.
KEGGi cel:CELE_C01B7.6.
UCSCi C01B7.6. c. elegans.

Organism-specific databases

CTDi 179259.
WormBasei C01B7.6 ; CE06730 ; WBGene00004457 ; rpm-1.

Phylogenomic databases

eggNOGi NOG240798.
GeneTreei ENSGT00390000011403.
HOGENOMi HOG000016145.
InParanoidi Q17551.
KOi K10693.
OMAi LPMIFNS.
OrthoDBi EOG75B84C.
PhylomeDBi Q17551.

Enzyme and pathway databases

UniPathwayi UPA00143 .
SignaLinki Q17551.

Miscellaneous databases

NextBioi 904596.
PROi Q17551.

Family and domain databases

Gene3Di 2.130.10.30. 1 hit.
2.60.120.260. 1 hit.
3.30.40.10. 1 hit.
InterProi IPR004939. APC_su10/DOC_dom.
IPR008979. Galactose-bd-like.
IPR027047. Highwire/Pam/Rpm-1.
IPR012983. PHR.
IPR009091. RCC1/BLIP-II.
IPR000408. Reg_chr_condens.
IPR000315. Znf_B-box.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
PANTHERi PTHR12846:SF17. PTHR12846:SF17. 1 hit.
Pfami PF08005. PHR. 2 hits.
PF00415. RCC1. 1 hit.
PF00643. zf-B_box. 1 hit.
PF13639. zf-RING_2. 1 hit.
[Graphical view ]
SMARTi SM00336. BBOX. 1 hit.
SM00184. RING. 1 hit.
[Graphical view ]
SUPFAMi SSF49785. SSF49785. 1 hit.
SSF50985. SSF50985. 2 hits.
PROSITEi PS51284. DOC. 1 hit.
PS00626. RCC1_2. 1 hit.
PS50012. RCC1_3. 1 hit.
PS50119. ZF_BBOX. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Regulation of presynaptic terminal organization by C. elegans RPM-1, a putative guanine nucleotide exchanger with a RING-H2 finger domain."
    Zhen M., Huang X., Bamber B., Jin Y.
    Neuron 26:331-343(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, TISSUE SPECIFICITY, MUTAGENESIS OF ARG-3597 AND CYS-3675.
    Strain: Bristol N21 Publication.
  2. "rpm-1, a conserved neuronal gene that regulates targeting and synaptogenesis in C. elegans."
    Schaefer A.M., Hadwiger G.D., Nonet M.L.
    Neuron 26:345-356(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, DISRUPTION PHENOTYPE.
    Strain: Bristol N21 Publication.
  3. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.
  4. Bienvenut W.V.
    Submitted (MAR-2005) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 86-99; 341-351; 621-629; 736-749; 834-847; 858-865; 1045-1056; 1084-1093; 1225-1237; 1281-1290; 1426-1434; 1441-1480; 1588-1603; 1961-1988; 2089-2097; 2103-2122; 2171-2183; 2186-2201; 2408-2416 AND 2573-2588, IDENTIFICATION BY MASS SPECTROMETRY.
  5. "Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development."
    Nakata K., Abrams B., Grill B., Goncharov A., Huang X., Chisholm A.D., Jin Y.
    Cell 120:407-420(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.

Entry informationi

Entry nameiRPM1_CAEEL
AccessioniPrimary (citable) accession number: Q17551
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3