Q17348 (SMD3_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Small nuclear ribonucleoprotein Sm D3
Short name=Sm-D3

Alternative name(s):
snRNP core protein D3

Gene names

Name:	snr-1
ORF Names:	Y116A8C.42

Organism

Caenorhabditis elegans [Reference proteome]

Taxonomic identifier

6239 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length	136 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Required for pre-mRNA splicing. Required for snRNP biogenesis By similarity.
Subcellular location	Nucleus By similarity.
Sequence similarities	Belongs to the snRNP core protein family.

Ontologies

Keywords
Biological process	mRNA processing mRNA splicing
Cellular component	Nucleus
Molecular function	Ribonucleoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	RNA splicing Inferred from electronic annotation. Source: UniProtKB-KW mRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	P granule Inferred from direct assay PubMed 12225665. Source: WormBase nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 136	136	Small nuclear ribonucleoprotein Sm D3		PRO_0000122217
Experimental info
	Sequence conflict	15 – 16	2	EG → RS in AAA65451. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q17348 [UniParc]. Last modified June 20, 2002. Version 2. Checksum: B0424DD28CB84E8C	FASTA	136	14,812
	10 20 30 40 50 60 MTSVGVPIKI LHEAEGHMVT LETVTGEVYR GKLSEAEDNM NCQLAETVVT FRDGRSHQLD 70 80 90 100 110 120 NVFIRGNKIR FMILPDMLKN APMFKNIGRA QKGAIGMGLG GLDQRGRGRG TAFRRPMGRG 130 GPRGMSRPGG APTFRG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2.
[2]	Winge P. Submitted (MAR-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 15-85.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL117204 Genomic DNA. Translation: CAB55132.1. U23937 mRNA. Translation: AAA65451.1.
PIR	T31498.
RefSeq	NP_503027.1. NM_070626.4.
3D structure databases
ProteinModelPortal	Q17348.
SMR	Q17348. Positions 5-76.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q17348. 1 interaction.
STRING	6239.Y116A8C.42.2.
Proteomic databases
PaxDb	Q17348.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	Y116A8C.42.1; Y116A8C.42.1; Y116A8C.42. Y116A8C.42.2; Y116A8C.42.2; Y116A8C.42.
GeneID	178483.
KEGG	cel:CELE_Y116A8C.42.
UCSC	Y116A8C.42.1. c. elegans.
Organism-specific databases
CTD	178483.
WormBase	Y116A8C.42; CE23346; WBGene00004914; snr-1.
Phylogenomic databases
eggNOG	COG1958.
GeneTree	ENSGT00610000086153.
HOGENOM	HOG000182712.
InParanoid	Q17348.
KO	K11088.
OMA	ESIPIKV.
Family and domain databases
InterPro	IPR027141. LSm4/Sm_D1/D3. IPR010920. LSM_dom. IPR001163. Ribonucl_LSM. IPR006649. Ribonucl_LSM_euk/arc. [Graphical view]
PANTHER	PTHR23338. PTHR23338. 1 hit.
Pfam	PF01423. LSM. 1 hit. [Graphical view]
SMART	SM00651. Sm. 1 hit. [Graphical view]
SUPFAM	SSF50182. Sm_like_riboprot. 1 hit.
ProtoNet	Search...
Other
NextBio	901312.

Entry information

Entry name

SMD3_CAEEL

Accession

Primary (citable) accession number: Q17348
Secondary accession number(s): Q9U2U5

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	June 20, 2002
Last modified:	May 1, 2013
This is version 85 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Caenorhabditis annotation project