Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Fatty acid-binding protein

Gene
N/A
Organism
Blomia tropicalis (Mite)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Binds the natural fluorescent fatty acid cis-parinaric acid and oleic acid by competition, but not retinol, retinoic acid, cholesterol, dansylated or anthroxylated fatty acids such as dansyl-DL-aminocaprylic acid and 12-(9-anthroyloxy)-stereate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei105Fatty acidBy similarity1

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandLipid-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Fatty acid-binding protein
Alternative name(s):
Bt6
Allergen: Blo t 13
OrganismiBlomia tropicalis (Mite)
Taxonomic identifieri40697 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataGlycyphagoideaEchimyopodidaeBlomia

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei150 Blo t 13
3150 Blo t 13.0101

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000674201 – 130Fatty acid-binding proteinAdd BLAST130

Proteomic databases

PRIDEiQ17284

Structurei

3D structure databases

ProteinModelPortaliQ17284
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni125 – 127Fatty acid bindingBy similarity3

Domaini

Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.By similarity

Sequence similaritiesi

Family and domain databases

Gene3Di2.40.128.20, 1 hit
InterProiView protein in InterPro
IPR012674 Calycin
IPR000463 Fatty_acid-bd
IPR031259 ILBP
IPR000566 Lipocln_cytosolic_FA-bd_dom
PANTHERiPTHR11955 PTHR11955, 1 hit
PfamiView protein in Pfam
PF00061 Lipocalin, 1 hit
PRINTSiPR00178 FATTYACIDBP
SUPFAMiSSF50814 SSF50814, 1 hit
PROSITEiView protein in PROSITE
PS00214 FABP, 1 hit

Sequencei

Sequence statusi: Complete.

Q17284-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPIEGKYKLE KSDNFDKFLD ELGVGFMVKT AAKTLKPTLE VDVQGDTYVF
60 70 80 90 100
RSLSTFKNTE IKFKLGEEFE EDRADGKRVK TVVNKEGDNK FIQTQYGDKE
110 120 130
VKIVRDFQGD DVVVTASVGD VTSVRTYKRI
Length:130
Mass (Da):14,800
Last modified:November 1, 1996 - v1
Checksum:iF9CFDA2BC8AE4879
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U58106 mRNA Translation: AAC80579.1

Similar proteinsi

Entry informationi

Entry nameiFABP_BLOTA
AccessioniPrimary (citable) accession number: Q17284
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health