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Protein

Major allergen Blo t 12

Gene
N/A
Organism
Blomia tropicalis (Mite)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Chitin-binding

Protein family/group databases

CAZyiCBM14. Carbohydrate-Binding Module Family 14.

Names & Taxonomyi

Protein namesi
Recommended name:
Major allergen Blo t 12
Alternative name(s):
Allergen: Blo t 12
OrganismiBlomia tropicalis (Mite)
Taxonomic identifieri40697 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataGlycyphagoideaEchimyopodidaeBlomia

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei149. Blo t 12.
3149. Blo t 12.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000002067521 – 144Major allergen Blo t 12Add BLAST124

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi127 ↔ 140PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Structurei

Secondary structure

1144
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi81 – 86Combined sources6
Beta strandi89 – 94Combined sources6
Beta strandi96 – 102Combined sources7
Beta strandi109 – 116Combined sources8
Beta strandi119 – 126Combined sources8
Beta strandi131 – 134Combined sources4
Turni135 – 138Combined sources4
Beta strandi139 – 142Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MFKNMR-A81-144[»]
SMRiQ17282.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini92 – 144Chitin-binding type-2PROSITE-ProRule annotationAdd BLAST53

Sequence similaritiesi

Contains 1 chitin-binding type-2 domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.170.140.10. 1 hit.
InterProiIPR002557. Chitin-bd_dom.
[Graphical view]
PfamiPF01607. CBM_14. 1 hit.
[Graphical view]
SUPFAMiSSF57625. SSF57625. 1 hit.
PROSITEiPS50940. CHIT_BIND_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q17282-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSVLIFLVA IALFSANIVS ADEQTTRGRH TEPDDHHEKP TTQCTHEETT
60 70 80 90 100
STQHHHEEVV TTQTPHHEEK TTTEETHHSD DLIVHEGGKT YHVVCHEEGP
110 120 130 140
IHIQEMCNKY IICSKSGSLW YITVMPCSIG TKFDPISRNC VLDN
Length:144
Mass (Da):16,326
Last modified:November 1, 1997 - v1
Checksum:iD901F1DA5749F7C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U27479 mRNA. Translation: AAA78904.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U27479 mRNA. Translation: AAA78904.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MFKNMR-A81-144[»]
SMRiQ17282.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei149. Blo t 12.
3149. Blo t 12.0101.
CAZyiCBM14. Carbohydrate-Binding Module Family 14.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.170.140.10. 1 hit.
InterProiIPR002557. Chitin-bd_dom.
[Graphical view]
PfamiPF01607. CBM_14. 1 hit.
[Graphical view]
SUPFAMiSSF57625. SSF57625. 1 hit.
PROSITEiPS50940. CHIT_BIND_II. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiALL12_BLOTA
AccessioniPrimary (citable) accession number: Q17282
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.