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Protein
Submitted name:

Cadherin homolog

Gene
N/A
Organism
Botryllus schlosseri (Star ascidian) (Alcyonium schlosseri)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Cadherins are calcium-dependent cell adhesion proteins.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell adhesionUniRule annotationSAAS annotation

Keywords - Ligandi

CalciumUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin homologImported
OrganismiBotryllus schlosseri (Star ascidian) (Alcyonium schlosseri)Imported
Taxonomic identifieri30301 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaStolidobranchiaStyelidaeBotryllus

Subcellular locationi

  • Cell membrane UniRule annotationSAAS annotation; Single-pass type I membrane protein UniRule annotationSAAS annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei728 – 75427HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence analysisAdd
BLAST
Chaini18 – 906889Sequence analysisPRO_5004185245Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ17281.
SMRiQ17281. Positions 837-901.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini186 – 26580CadherinInterPro annotationAdd
BLAST
Domaini266 – 382117CadherinInterPro annotationAdd
BLAST
Domaini407 – 49892CadherinInterPro annotationAdd
BLAST
Domaini499 – 607109CadherinInterPro annotationAdd
BLAST

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di2.60.40.60. 4 hits.
4.10.900.10. 1 hit.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR000233. Cadherin_cytoplasmic-dom.
IPR027397. Catenin_binding_dom.
[Graphical view]
PfamiPF00028. Cadherin. 4 hits.
PF01049. Cadherin_C. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 4 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 5 hits.
PROSITEiPS00232. CADHERIN_1. 3 hits.
PS50268. CADHERIN_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q17281-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIFWKFLTF FPITVFNLPL KIPSSHVHFT KNSFYLVSWN LLKPTDLCPN
60 70 80 90 100
KAKPNQTWFM SKVYDRSQNF PNMDITLSGF PVTIMPSRQT VQSTFRELRV
110 120 130 140 150
DVCSLKNNNC FFLFVMQLSC ENKSRYTNLN KLRSPREAYK LFGGMGPSIP
160 170 180 190 200
QISTAVLLAV HYAEGQWTYL NKESQRDPFT RRLKVVKIHS EDPTTVTYDI
210 220 230 240 250
SGDFGTKFDI DHESGQIWQV EAVDRETKDR YTITATSADA NGNPTEDPVR
260 270 280 290 300
FDIVVTDIND NYPVFVESSL TGSVEELHDT GPDSTPFMQV KATDEDLGFN
310 320 330 340 350
AEIRFKIEDG SDTPESPSGN RFIIDPVSGW VRVNGDDLNY ESNPVVRFNV
360 370 380 390 400
IAVDNNGGPG SNEKKSEVVV SVTDSNDHAP EFGSSYRLNH CRKYQNLVPH
410 420 430 440 450
CIDVRYDTDE GVNKKVYFEI LDGNTGGAFT IVSKPSATGQ SLGELQLVKP
460 470 480 490 500
LDFESGIVSY KLKIKAYNKD ASNAADVAYA TESTLSITVI DANEPPIFRD
510 520 530 540 550
TPYNYRRTEG PAPAEPIPII QVHAEDIDFN KNQTVTYSLE DPENWFDIVA
560 570 580 590 600
TTGQITLTGA LDREATANGV YHLKVIATDN YDHGNPASGS EEVAITIEDI
610 620 630 640 650
NDNPPAPDWG QEVATAYVCE KATNRTARHI KATDPDSAVN GPPFTLRLDD
660 670 680 690 700
SVDKPSGVFE AVDDDSVNLI AEFSDYGLSS GSATVSLIFT VTDGGTVSQT
710 720 730 740 750
ARTTLTATTI CKCGDDGEFT CKDATAAAFP YAIIIAVIAV ILLIAILVFA
760 770 780 790 800
VVTYKRRQAA MILKEPFFDD EDDIRETVQV YQEEGGEEDQ DTYDLSALRG
810 820 830 840 850
PLLEDPNQPI RKTQMPLIQQ APRPRRPNAP DDITNIIGEA KDAADEDPSA
860 870 880 890 900
PPFDSLLVFD YEGAGSDAGS LSSINTATTD GSVDYDYLND WGPRFNRLAG

MLYEGS
Length:906
Mass (Da):100,154
Last modified:November 1, 1996 - v1
Checksum:iB09E3F84F9AF18D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U61755 Genomic DNA. Translation: AAB88396.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U61755 Genomic DNA. Translation: AAB88396.1.

3D structure databases

ProteinModelPortaliQ17281.
SMRiQ17281. Positions 837-901.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.40.60. 4 hits.
4.10.900.10. 1 hit.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR000233. Cadherin_cytoplasmic-dom.
IPR027397. Catenin_binding_dom.
[Graphical view]
PfamiPF00028. Cadherin. 4 hits.
PF01049. Cadherin_C. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 4 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 5 hits.
PROSITEiPS00232. CADHERIN_1. 3 hits.
PS50268. CADHERIN_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning and characterization of BS-cadherin, a novel cadherin from the colonial urochordate Botryllus schlosseri."
    Levi L., Douek J., Osman M., Bosch T.C., Rinkevich B.
    Gene 200:117-123(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ17281_BOTSH
AccessioniPrimary (citable) accession number: Q17281
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.