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Q17237

- SGF3_BOMMO

UniProt

Q17237 - SGF3_BOMMO

Protein

Silk gland factor 3

Gene

SGF3

Organism
Bombyx mori (Silk moth)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Involved in the transcriptional regulation of sericin-1 gene.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi241 – 30060HomeoboxPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. cell differentiation Source: UniProtKB-KW
    2. nervous system development Source: UniProtKB-KW
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator, Developmental protein

    Keywords - Biological processi

    Differentiation, Neurogenesis, Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Silk gland factor 3
    Short name:
    SGF-3
    Alternative name(s):
    POU domain protein M1
    Gene namesi
    Name:SGF3
    Synonyms:POU-M1
    OrganismiBombyx mori (Silk moth)
    Taxonomic identifieri7091 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaLepidopteraGlossataDitrysiaBombycoideaBombycidaeBombycinaeBombyx
    ProteomesiUP000005204: Unplaced

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 351351Silk gland factor 3PRO_0000100776Add
    BLAST

    Expressioni

    Tissue specificityi

    Restricted to the middle silk gland.

    Developmental stagei

    Expression differentially regulated in the posterior and middle silk glands during the fourth molt/fifth intermolt.

    Structurei

    3D structure databases

    ProteinModelPortaliQ17237.
    SMRiQ17237. Positions 155-301.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini149 – 22375POU-specificPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation
    Contains 1 POU-specific domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Homeobox

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    1.10.260.40. 1 hit.
    InterProiIPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR010982. Lambda_DNA-bd_dom.
    IPR013847. POU.
    IPR000327. POU_specific.
    [Graphical view]
    PfamiPF00046. Homeobox. 1 hit.
    PF00157. Pou. 1 hit.
    [Graphical view]
    PRINTSiPR00028. POUDOMAIN.
    SMARTiSM00389. HOX. 1 hit.
    SM00352. POU. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    SSF47413. SSF47413. 1 hit.
    PROSITEiPS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00035. POU_1. 1 hit.
    PS00465. POU_2. 1 hit.
    PS51179. POU_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q17237-1 [UniParc]FASTAAdd to Basket

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    MAATTYMPAE MELGNIGGYH AASPRSAEPA DMKYQHPLHS GGSPSPGAPV    50
    IGNPWTSLPP ADPWAMHQHH AHAHQPDVKP PPAPHDHRHL QHAAHGWHAP 100
    VVSPHYGAAR PSHCMEDTQC PCTNTICSET SSPRDPLHHH AMERDQPEED 150
    TPTSDDLEAF AKQFKQRRIK LGFTQADVGL ALGTLYGNVF SQTTICRFEA 200
    LQLSFKNMCK LKPLLQKWLE EADSTTGSPT SIDKIAAQGR KRKKRTSIEV 250
    SVKGALEQHF HKQPKPSAQE ITSLADSLQL EKEVVRVWFC NRRQKEKRMT 300
    PPNTLGGEMM EGMGHAHYGH GDVHGSPLQH SPPGLSPQHG LPQGAHTLAA 350
    H 351
    Length:351
    Mass (Da):38,591
    Last modified:November 1, 1996 - v1
    Checksum:iA6DFA4A59E9322B6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M64781 mRNA. Translation: AAA27841.1.
    PIRiA48763.
    UniGeneiBmo.755.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M64781 mRNA. Translation: AAA27841.1 .
    PIRi A48763.
    UniGenei Bmo.755.

    3D structure databases

    ProteinModelPortali Q17237.
    SMRi Q17237. Positions 155-301.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    1.10.260.40. 1 hit.
    InterProi IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR010982. Lambda_DNA-bd_dom.
    IPR013847. POU.
    IPR000327. POU_specific.
    [Graphical view ]
    Pfami PF00046. Homeobox. 1 hit.
    PF00157. Pou. 1 hit.
    [Graphical view ]
    PRINTSi PR00028. POUDOMAIN.
    SMARTi SM00389. HOX. 1 hit.
    SM00352. POU. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    SSF47413. SSF47413. 1 hit.
    PROSITEi PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00035. POU_1. 1 hit.
    PS00465. POU_2. 1 hit.
    PS51179. POU_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular cloning of a POU domain-containing factor involved in the regulation of the Bombyx sericin-1 gene."
      Fukuta M., Matsuno K., Hui C.-C., Nagata T., Takiya S., Xu P.-X., Ueno K., Suzuki Y.
      J. Biol. Chem. 268:19471-19475(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: Kinshu X Showa.
      Tissue: Silk gland.

    Entry informationi

    Entry nameiSGF3_BOMMO
    AccessioniPrimary (citable) accession number: Q17237
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3