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Q17237

- SGF3_BOMMO

UniProt

Q17237 - SGF3_BOMMO

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Protein

Silk gland factor 3

Gene

SGF3

Organism
Bombyx mori (Silk moth)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Involved in the transcriptional regulation of sericin-1 gene.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi241 – 30060HomeoboxPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. cell differentiation Source: UniProtKB-KW
  2. nervous system development Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator, Developmental protein

Keywords - Biological processi

Differentiation, Neurogenesis, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Silk gland factor 3
Short name:
SGF-3
Alternative name(s):
POU domain protein M1
Gene namesi
Name:SGF3
Synonyms:POU-M1
OrganismiBombyx mori (Silk moth)
Taxonomic identifieri7091 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaLepidopteraGlossataDitrysiaBombycoideaBombycidaeBombycinaeBombyx
ProteomesiUP000005204: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 351351Silk gland factor 3PRO_0000100776Add
BLAST

Expressioni

Tissue specificityi

Restricted to the middle silk gland.

Developmental stagei

Expression differentially regulated in the posterior and middle silk glands during the fourth molt/fifth intermolt.

Structurei

3D structure databases

ProteinModelPortaliQ17237.
SMRiQ17237. Positions 155-301.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini149 – 22375POU-specificPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation
Contains 1 POU-specific domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

InParanoidiQ17237.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_specific.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q17237-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAATTYMPAE MELGNIGGYH AASPRSAEPA DMKYQHPLHS GGSPSPGAPV
60 70 80 90 100
IGNPWTSLPP ADPWAMHQHH AHAHQPDVKP PPAPHDHRHL QHAAHGWHAP
110 120 130 140 150
VVSPHYGAAR PSHCMEDTQC PCTNTICSET SSPRDPLHHH AMERDQPEED
160 170 180 190 200
TPTSDDLEAF AKQFKQRRIK LGFTQADVGL ALGTLYGNVF SQTTICRFEA
210 220 230 240 250
LQLSFKNMCK LKPLLQKWLE EADSTTGSPT SIDKIAAQGR KRKKRTSIEV
260 270 280 290 300
SVKGALEQHF HKQPKPSAQE ITSLADSLQL EKEVVRVWFC NRRQKEKRMT
310 320 330 340 350
PPNTLGGEMM EGMGHAHYGH GDVHGSPLQH SPPGLSPQHG LPQGAHTLAA

H
Length:351
Mass (Da):38,591
Last modified:November 1, 1996 - v1
Checksum:iA6DFA4A59E9322B6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M64781 mRNA. Translation: AAA27841.1.
PIRiA48763.
UniGeneiBmo.755.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M64781 mRNA. Translation: AAA27841.1 .
PIRi A48763.
UniGenei Bmo.755.

3D structure databases

ProteinModelPortali Q17237.
SMRi Q17237. Positions 155-301.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

InParanoidi Q17237.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProi IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_specific.
[Graphical view ]
Pfami PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view ]
PRINTSi PR00028. POUDOMAIN.
SMARTi SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEi PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning of a POU domain-containing factor involved in the regulation of the Bombyx sericin-1 gene."
    Fukuta M., Matsuno K., Hui C.-C., Nagata T., Takiya S., Xu P.-X., Ueno K., Suzuki Y.
    J. Biol. Chem. 268:19471-19475(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: Kinshu X Showa.
    Tissue: Silk gland.

Entry informationi

Entry nameiSGF3_BOMMO
AccessioniPrimary (citable) accession number: Q17237
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3