Q170W7 (Q170W7_AEDAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminolevulinic acid synthase EMBL EAT40489.1

Gene names

ORF Names:

AAEL007787, AaeL_AAEL007787 EMBL EAT40489.1

Organism

Aedes aegypti (Yellowfever mosquito) (Culex aegypti)

Taxonomic identifier

7159 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicoidea › Culicidae › Culicinae › Aedini › Aedes › Stegomyia

Protein attributes

Sequence length	571 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tetrapyrrole biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	5-aminolevulinate synthase activity Inferred from electronic annotation. Source: InterPro pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity, transferring nitrogenous groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q170W7 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: 241335BA871E2A77	FASTA	571	62,386
	10 20 30 40 50 60 MPCPFLTRLS TSYVRNYAPA LLKTYGSQCP VVARTISSLQ NPPAGTGADA AGAGSVATKK 70 80 90 100 110 120 KEPVATPKQP EVKTPSRNLS SLQQPKAKEE AKKCPFLSSA APHVKELGAE SVDVPATRPF 130 140 150 160 170 180 QYEEFFHEQI MRKKKDHSYR VFKKVNRLAE AGKFPKALEY SWGERPITVW CSNDYLGMSC 190 200 210 220 230 240 HPEVKKAVAN ALETYGAGAG GTRNISGNSL NHENLESRLA QLHEKEGALL FTSCFVANDS 250 260 270 280 290 300 TLFTLAKALP GCHIFSDAGN HASMIQGIKN SGVPKHIFRH NDPAHLRELL SKVDKSLPKI 310 320 330 340 350 360 VAFETVHSMT GAICPLEELC DVAHEFGALT FVDEVHAVGL YGDHGAGVGE REGLLHKMDI 370 380 390 400 410 420 ISGTLGKAFG NVGGYIASTS LLIDMVRSYA AGFIFTTSLP PTVLCGALKA VNILASDEGR 430 440 450 460 470 480 ELRTRHQENV RYLRGLLQRE GFPVEHTPSH IIPVKIGNPA QCTELSDLMI KRFGHYIQAI 490 500 510 520 530 540 NYPTVARGEE KLRLAPTPHH TKEMMDILVR DMKIVWKDLG MPLNGSACTA ECTFCRKPLL 550 560 570 FDRFESRTKA SCAAEINCQI PNCPQIAAIA N

References

[1]

"Genome sequence of Aedes aegypti, a major arbovirus vector." Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J., Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P. , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W. Science 316:1718-1723(2007) [PubMed: 17510324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LVPib12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH477465 Genomic DNA. Translation: EAT40489.1.
RefSeq	XP_001658653.1. XM_001658603.1.
UniGene	Aae.17190.
3D structure databases
ProteinModelPortal	Q170W7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q170W7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AAEL007787-RA; AAEL007787-PA; AAEL007787.
GeneID	5569629.
KEGG	aag:AaeL_AAEL007787.
VectorBase	AAEL007787. Aedes aegypti.
Phylogenomic databases
eggNOG	inNOG06607.
GeneTree	EMGT00050000012949.
OMA	CPFLARM.
OrthoDB	EOG45HQCK.
PhylomeDB	Q170W7.
Family and domain databases
InterPro	IPR010961. 4pyrrol_synth_NH2levulA_synth. IPR004839. Aminotransferase_I/II. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00643.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01821. 5aminolev_synth. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q170W7_AEDAE

Accession

Primary (citable) accession number: Q170W7

Entry history

Integrated into UniProtKB/TrEMBL:	July 25, 2006
Last sequence update:	July 25, 2006
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)