Q17077 (PBP1_ANTPE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Pheromone-binding protein 1 Short name=PBP 1 Alternative name(s): APR-1
Organism	Antheraea pernyi (Chinese oak silk moth)
Taxonomic identifier	7119 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Amphiesmenoptera › Lepidoptera › Glossata › Neolepidoptera › Heteroneura › Ditrysia › Obtectomera › Bombycoidea › Saturniiformes › Saturniidae › Saturniinae › Saturniini › Antheraea

Protein attributes

Sequence length	163 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	This major soluble protein in olfactory sensilla of male moths might serve to solubilize the extremely hydrophobic pheromone molecules and to transport pheromone through the aqueous lymph to receptors located on olfactory cilia.
Tissue specificity	Antenna.
Sequence similarities	Belongs to the PBP/GOBP family.

Ontologies

Keywords
Biological process	Pheromone response Transport
Domain	Signal
Ligand	Pheromone-binding
PTM	Disulfide bond
Gene Ontology (GO)
Biological_process	response to pheromone Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	pheromone binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Potential
	Chain	22 – 163	142	Pheromone-binding protein 1		PRO_0000012556
Amino acid modifications
	Disulfide bond	40 ↔ 75		By similarity
	Disulfide bond	71 ↔ 129		By similarity
	Disulfide bond	118 ↔ 138		By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q17077 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 3CFE4FE33E369C56	FASTA	163	18,086
	10 20 30 40 50 60 MLGKISLLLL PVFVAINLVH SSPEIIKNLS QNFCKAMDQC KQELNIPDSV IADLYNFWKD 70 80 90 100 110 120 DYVMTDRLAG CAINCMATKL DVVDPDGNLH HGNAKEFAMK HGADASMAQQ LVDIIHGCEK 130 140 150 160 SAPPNDDKCM KTIDVAMCFK KEIHKLNWVP DMDVVLGEVL AEV

References

[1]	"Primary structure of a pheromone-binding protein from Antheraea pernyi: homologies with other ligand-carrying proteins." Raming K., Krieger J., Breer H. J. Comp. Physiol. B 160:503-509(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Antenna.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X96773 mRNA. Translation: CAA65576.1.
PIR	S14269.
3D structure databases
ProteinModelPortal	Q17077.
SMR	Q17077. Positions 22-163.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.10.238.20. 1 hit.
InterPro	IPR006072. Odorant/phero-bd_Lep. IPR006170. PBP_GOBP. IPR023316. PBP_GOBP_dom. [Graphical view]
Pfam	PF01395. PBP_GOBP. 1 hit. [Graphical view]
PIRSF	PIRSF015604. Odorant/phero_bd. 1 hit.
PRINTS	PR00484. PBPGOBP.
SMART	SM00708. PhBP. 1 hit. [Graphical view]
SUPFAM	SSF47565. PBP_GOBP. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PBP1_ANTPE

Accession

Primary (citable) accession number: Q17077

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)