Q17042 (Q17042_ARGIR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Myosin heavy chain EMBL AAC46490.1
Organism	Argopecten irradians (Bay scallop) (Aequipecten irradians) EMBL AAC46490.1
Taxonomic identifier	31199 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Lophotrochozoa › Mollusca › Bivalvia › Pteriomorphia › Pectinoida › Pectinoidea › Pectinidae › Argopecten

Protein attributes

Sequence length	1951 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 IQ domain. SAAS SAAS004009 Contains 1 myosin head-like domain. SAAS SAAS004009

Ontologies

Keywords
Domain	Coiled coil SAAS SAAS004009
Ligand	ATP-binding SAAS SAAS004009 Actin-binding SAAS SAAS004009 Nucleotide-binding
Molecular function	Motor protein Myosin SAAS SAAS004009
Technical term	3D-structure PDB 1NKN
Gene Ontology (GO)
Cellular_component	myosin complex Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW motor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q17042 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 1FDC3D7D691C1410	FASTA	1,951	224,254
	10 20 30 40 50 60 MNIDFSDPDF QYLAVDRKKL MKEQTAAFDG KKNCWVPDEK EGFASAEIQS SKGDEITVKI 70 80 90 100 110 120 VADSSTRTVK KDDIQSMNPP KFEKLEDMAN MTYLNEASVL YNLRSRYTSG LIYTYSGLFC 130 140 150 160 170 180 IAVNPYRRLP IYTDSVIAKY RGKRKTEIPP HLFSVADNAY QNMVTDRENQ SCLITGESGA 190 200 210 220 230 240 GKTESTKKVI MYFARVAANL YKQKQEEPTT THARASNLED QIIEANPVLE AFGNAKTVRN 250 260 270 280 290 300 NNSSRFGKFI RIHFGPTGKI AGADIETYLL EKSRVTYQQS AERNYHIFYQ ICSNAIPELN 310 320 330 340 350 360 DVMLVTPDSG LYSFINQGCL TVDNIDDVEE FKLCDEAFDI LGFTKEEKQS MFKCTASILH 370 380 390 400 410 420 MGEMKFKQRP REEQAESDGT AEAEKVAFLC GINAGDLLKA LLKPKVKVGT EMVTKGQNMN 430 440 450 460 470 480 QVVNSVGALA KSLYDRMFNW LVRRVNKTLD TKAKRNYYIG VLDIAGFEIF DFNSFEQLCI 490 500 510 520 530 540 NYTNERLQQF FNHHMFILEQ EEYKKEGIAW EFIDFGMDLQ MCIDLIEKPM GILSILEEEC 550 560 570 580 590 600 MFPKADDKSF QDKLYQNHMG KNRMFTKPGK PTRPNQGPAH FELHHYAGNV PYSITGWLEK 610 620 630 640 650 660 NKDPINENVV ALLGASKEPL VAELFKAPEE PAGGGKKKKG KSSAFQTISA VHRESLNKLM 670 680 690 700 710 720 KNLYSTHPHF VRCIIPNELK QPGLVDAELV LHQLQCNGVL EGIRICRKGF PSRLIYSEFK 730 740 750 760 770 780 QRYSILAPNA IPQGFVDGKT VSEKILAGLQ MDPAEYRLGT TKVFFKAGVL GNLEEMRDER 790 800 810 820 830 840 LSKIISMFQA HIRGYLIRKA YKKLQDQRIG LSVIQRNIRK WLVLRNWQWW KLYSKVKPLL 850 860 870 880 890 900 SIARQEEEMK EQLKQMDKMK EDLAKTERIK KELEEQNVTL LEQKNDLFLQ LQTLEDSMGD 910 920 930 940 950 960 QEERVEKLIM QKADFESQIK ELEERLLDEE DAAADLEGIK KKMEADNANL KKDIGDLENT 970 980 990 1000 1010 1020 LQKAEQDKAH KDNQISTLQG EISQQDEHIG KLNKEKKALE EANKKTSDSL QAEEDKCNHL 1030 1040 1050 1060 1070 1080 NKLKAKLEQA LDELEDNLER EKKVRGDVEK AKRKVEQDLK STQENVEDLE RVKRELEENV 1090 1100 1110 1120 1130 1140 RRKEAEISSL NSKLEDEQNL VSQLQRKIKE LQARIEELEE ELEAERNARA KVEKQRAELN 1150 1160 1170 1180 1190 1200 RELEELGERL DEAGGATSAQ IELNKKREAE LLKIRRDLEE ASLQHEAQIS ALRKKHQDAA 1210 1220 1230 1240 1250 1260 NEMADQVDQL QKVKSKSEKE KQQLRSEVED LQAQIQHISK NKGCSEKVMK QFESQMSDLN 1270 1280 1290 1300 1310 1320 ARLEDSQRSI NELQSQKSRL QAENSDLTRQ LEDAEHRVSV LSKEKSQLSS QLEDARRSLE 1330 1340 1350 1360 1370 1380 EETRARSKLQ NEVRNMHADM DAIREQLEEE QESKSDVQRQ LSKANNEIQQ WRSKFESEGA 1390 1400 1410 1420 1430 1440 NRTEELEDQK RKLLGKLSEA EQTTEAANAK CSALEKAKSR LQQELEDMSI EVDRANASVN 1450 1460 1470 1480 1490 1500 QMEKKQRAFD KTTAEWQAKV NSLQSELENS QKESRGYSAE LYRIKASIEE YQDSIGALRR 1510 1520 1530 1540 1550 1560 ENKNLADEIH DLTDQLSEGG RSTHELDKAR RRLEMEKEEL QAALEEAEGA LEQEEAKVMR 1570 1580 1590 1600 1610 1620 AQLEIATVRN EIDKRIQEKE EEFDNTRRNH QRALESMQAS LEAEAKGKAD AMRIKKKLEQ 1630 1640 1650 1660 1670 1680 DINELEVALD ASNRGKAEME KTVKRYQQQI REMQTSIEEE QRQRDEARES YNMAERRCTL 1690 1700 1710 1720 1730 1740 MSGEVEELRA ALEQAERARK ASDNELADAN DRVNELTSQV SSVQGQKRKL EGDINAMQTD 1750 1760 1770 1780 1790 1800 LDEMHGELKG ADERCKKAMA DAARLADELR AEQDHSNQVE KVRKNLESQV KEFQIRLDEA 1810 1820 1830 1840 1850 1860 EASSLKGGKK MIQKLESRVH ELEAELDNEQ RRHAETQKNM RKADRRLKEL AFQADEDRKN 1870 1880 1890 1900 1910 1920 QERLQELIDK LNAKIKTFKR QVEEAEEIAA INLAKYRKAQ HELEEAEERA DTADSTLQKF 1930 1940 1950 RAKSRSSVSV QRSSVSVSAS NAAHVAHHHV E

References

[1]	"Scallop striated and smooth muscle myosin heavy-chain isoforms are produced by alternative RNA splicing from a single gene." Nyitray L., Jancso A., Ochiai Y., Graf L., Szent-Gyorgyi A.G. Proc. Natl. Acad. Sci. U.S.A. 91:12686-12690(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Muscle EMBL AAC46490.1.
[2]	"Visualization of an unstable coiled coil from the scallop myosin rod." Li Y., Brown J.H., Reshetnikova L., Blazsek A., Farkas L., Nyitray L., Cohen C. Nature 424:341-345(2003) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) OF 838-888.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U09782 mRNA. Translation: AAC46490.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1NKN	X-ray	2.50	A/B/C/D	838-888	[»]

ProteinModelPortal

Q17042.

SMR

Q17042. Positions 6-924.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

4.10.270.10. 1 hit.

InterPro

IPR000048. IQ_motif_EF-hand-BS.
IPR027401. Myosin-like_IQ_dom.
IPR001609. Myosin_head_motor_dom.
IPR004009. Myosin_N.
IPR002928. Myosin_tail.
IPR027417. P-loop_NTPase.
[Graphical view]

Pfam

PF00063. Myosin_head. 1 hit.
PF02736. Myosin_N. 1 hit.
PF01576. Myosin_tail_1. 1 hit.
[Graphical view]

PRINTS

PR00193. MYOSINHEAVY.

SMART

SM00015. IQ. 1 hit.
SM00242. MYSc. 1 hit.
[Graphical view]

SUPFAM

SSF52540. SSF52540. 1 hit.

PROSITE

PS50096. IQ. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q17042.

Entry information

Entry name

Q17042_ARGIR

Accession

Primary (citable) accession number: Q17042

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	May 29, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)