Q16ZR3 (Q16ZR3_AEDAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
AAEL008085-PA EMBL EAT40158.1

Submitted name:
Serine protease V EMBL ACV07664.1

Gene names

ORF Names:

AAEL008085

Organism

Aedes aegypti (Yellowfever mosquito) (Culex aegypti) [Reference proteome] EMBL EAT40158.1

Taxonomic identifier

7159 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicimorpha › Culicoidea › Culicidae › Culicinae › Aedini › Aedes › Stegomyia

Protein attributes

Sequence length	281 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the peptidase S1 family. RuleBase RU000360

Ontologies

Keywords
Molecular function	Hydrolase Protease EMBL ACV07664.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	serine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q16ZR3 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: 216DF2693624E83C	FASTA	281	29,761
	10 20 30 40 50 60 MWFSVKISKL LLLVAVSSVA ASVDNDVKII GGFPAQQSST RHQVSIRQKS VDLALFGSGH 70 80 90 100 110 120 FCGGSLINDR TVLTAALCLV NEEGKRRVAS YFRVVGGGLN RLLQTQNTVI ANVSKVIIHE 130 140 150 160 170 180 NYDPNTVAND IGLLILDKPV ESSHQTLRTI ELATSRPVAG SICQTTGWGT TVYGLPMVTV 190 200 210 220 230 240 ELMAVNVTIQ PIESCNGTGS YNGIILDGML CAGEITGGKD SCQGDSGGPL VCGGFLAGIV 250 260 270 280 SYGKGCGLAS YPGIYSDVVH FREWIDKHKH TSGGENVKFT V

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Loftus B.J., Nene V.M., Hannick L.I., Bidwell S., Haas B., Amedeo P., Orvis J., Wortman J.R., White O.R., Salzberg S., Shumway M., Koo H., Zhao Y., Holmes M., Miller J., Schatz M., Pop M., Pai G. , Utterback T., Rogers Y.-H., Kravitz S., Fraser C.M. Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Liverpool EMBL EAT40158.1.
[2]	"Genome sequence of Aedes aegypti, a major arbovirus vector." Nene V., Wortman J.R., Lawson D., Haas B., Kodira C., Tu Z.J., Loftus B., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P. , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., Debruyn B., Decaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston J.S., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'leary S., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.H., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M., Vanzee J.P., Verjovski-Almeida S., Werner D., White O., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Birren B., Fraser-Liggett C.M., Severson D.W. Science 316:1718-1723(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Liverpool EMBL EAT40158.1 and LVPib12.
[3]	"Expression profiling and comparative analyses of seven midgut serine proteases from the yellow fever mosquito, Aedes aegypti." Brackney D.E., Isoe J., W C B.IV., Zamora J., Foy B.D., Miesfeld R.L., Olson K.E. J. Insect Physiol. 56:736-744(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Rockefeller EMBL ACV07664.1.
[4]	VectorBase Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Liverpool EMBL EAT40158.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GQ398047 mRNA. Translation: ACV07664.1. CH477485 Genomic DNA. Translation: EAT40158.1.
RefSeq	XP_001653092.1. XM_001653042.1.
UniGene	Aae.23401.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AAEL008085-RA; AAEL008085-PA; AAEL008085.
GeneID	5570112.
KEGG	aag:AaeL_AAEL008085.
VectorBase	AAEL008085. Aedes aegypti.
Phylogenomic databases
HOGENOM	HOG000251820.
KO	K01312.
OrthoDB	EOG4BVQ9N.
PhylomeDB	Q16ZR3.
Family and domain databases
InterPro	IPR001254. Peptidase_S1. IPR018114. Peptidase_S1_AS. IPR001314. Peptidase_S1A. IPR009003. Trypsin-like_Pept_dom. [Graphical view]
Pfam	PF00089. Trypsin. 1 hit. [Graphical view]
PRINTS	PR00722. CHYMOTRYPSIN.
SMART	SM00020. Tryp_SPc. 1 hit. [Graphical view]
SUPFAM	SSF50494. Pept_Ser_Cys. 1 hit.
PROSITE	PS50240. TRYPSIN_DOM. 1 hit. PS00135. TRYPSIN_SER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q16ZR3_AEDAE

Accession

Primary (citable) accession number: Q16ZR3

Entry history

Integrated into UniProtKB/TrEMBL:	July 25, 2006
Last sequence update:	July 25, 2006
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)