Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alpha-amylase

Gene

AAEL008451

Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotationSAAS annotation

GO - Molecular functioni

  1. alpha-amylase activity Source: UniProtKB-EC
  2. cation binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotationSAAS annotation (EC:3.2.1.1UniRule annotationSAAS annotation)
Gene namesi
ORF Names:AAEL008451Imported
OrganismiAedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported
Taxonomic identifieri7159 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia
ProteomesiUP000008820: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliQ16YR2.
SMRiQ16YR2. Positions 21-456.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Phylogenomic databases

InParanoidiQ16YR2.
KOiK01176.
OMAiPNEHITL.
OrthoDBiEOG7RJPR2.
PhylomeDBiQ16YR2.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Q16YR2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKILASFLAV AFATLVSAQF DTHQWADRSG IVHLFEWRWN DIADECERFL
60 70 80 90 100
APRGYAGVQV SPPTENIIVS GRPWWERYQP ASYHLNTRSG SEAEFASMVR
110 120 130 140 150
RCNNVGVRIY VDIVINHMAA ISGQGTGGSQ VNGLNFPAVP YGANDFNPHC
160 170 180 190 200
EINNYNDPYQ VRNCWLVGLP DLALGTQWVR DRIVDLMNKC IGYGIAGFRV
210 220 230 240 250
DAVKHMWPGD LEHIYNRLNN LNTDHGFPGG ARPFITQEVI DLGGEAISKY
260 270 280 290 300
EYTHLGTVTE FRYSAEIGRV FHGRDRLAHL SNWGEQWGFL PSHLGLAFVD
310 320 330 340 350
NHDNQRGHGA GGDNVLTHKT PKNYKMASAF MLAHPYGIIR VMSSFFFDNG
360 370 380 390 400
DQGPPQDGNG NLIPPSINAD NSCGNGWACE HRWRQIYNMV GFRNAVRGTG
410 420 430 440 450
INDWWSNGNQ QIAFCRGGSG FVAFNLEGYD MNENLQTCLS AGTYCDVISG
460 470 480
SKEGGSLVLQ CKSVEMDVPI SIFRPKVMMV FWPSM
Length:485
Mass (Da):54,133
Last modified:July 25, 2006 - v1
Checksum:iDFE3F354E8356130
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477511 Genomic DNA. Translation: EAT39767.1.
RefSeqiXP_001653282.1. XM_001653232.1.
UniGeneiAae.17186.

Genome annotation databases

EnsemblMetazoaiAAEL008451-RA; AAEL008451-PA; AAEL008451.
GeneIDi5570646.
KEGGiaag:AaeL_AAEL008451.
VectorBaseiAAEL008451. Aedes aegypti.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477511 Genomic DNA. Translation: EAT39767.1.
RefSeqiXP_001653282.1. XM_001653232.1.
UniGeneiAae.17186.

3D structure databases

ProteinModelPortaliQ16YR2.
SMRiQ16YR2. Positions 21-456.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAAEL008451-RA; AAEL008451-PA; AAEL008451.
GeneIDi5570646.
KEGGiaag:AaeL_AAEL008451.
VectorBaseiAAEL008451. Aedes aegypti.

Phylogenomic databases

InParanoidiQ16YR2.
KOiK01176.
OMAiPNEHITL.
OrthoDBiEOG7RJPR2.
PhylomeDBiQ16YR2.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Aedes aegypti, a major arbovirus vector."
    Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J., Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.
    , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.
    Science 316:1718-1723(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LVPib12Imported.

Entry informationi

Entry nameiQ16YR2_AEDAE
AccessioniPrimary (citable) accession number: Q16YR2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: March 4, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.