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Protein

Alpha-amylase

Gene

AAEL008451

Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationSAAS annotation, Hydrolase

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotation (EC:3.2.1.1UniRule annotation)
Gene namesi
ORF Names:AAEL008451Imported
OrganismiAedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported
Taxonomic identifieri7159 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia
Proteomesi
  • UP000008820 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818Sequence analysisAdd
BLAST
Chaini19 – 485467Alpha-amylaseSequence analysisPRO_5004185254Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7159.AAEL008451-PA.

Structurei

3D structure databases

ProteinModelPortaliQ16YR2.
SMRiQ16YR2. Positions 21-456.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini29 – 393365AamyInterPro annotationAdd
BLAST
Domaini402 – 48584Aamy_CInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2212. Eukaryota.
COG0366. LUCA.
InParanoidiQ16YR2.
KOiK01176.
OMAiWCIVAGQ.
OrthoDBiEOG091G07V6.
PhylomeDBiQ16YR2.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase/branching_C.
IPR031319. A-amylase_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013780. Glyco_hydro_b.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Q16YR2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKILASFLAV AFATLVSAQF DTHQWADRSG IVHLFEWRWN DIADECERFL
60 70 80 90 100
APRGYAGVQV SPPTENIIVS GRPWWERYQP ASYHLNTRSG SEAEFASMVR
110 120 130 140 150
RCNNVGVRIY VDIVINHMAA ISGQGTGGSQ VNGLNFPAVP YGANDFNPHC
160 170 180 190 200
EINNYNDPYQ VRNCWLVGLP DLALGTQWVR DRIVDLMNKC IGYGIAGFRV
210 220 230 240 250
DAVKHMWPGD LEHIYNRLNN LNTDHGFPGG ARPFITQEVI DLGGEAISKY
260 270 280 290 300
EYTHLGTVTE FRYSAEIGRV FHGRDRLAHL SNWGEQWGFL PSHLGLAFVD
310 320 330 340 350
NHDNQRGHGA GGDNVLTHKT PKNYKMASAF MLAHPYGIIR VMSSFFFDNG
360 370 380 390 400
DQGPPQDGNG NLIPPSINAD NSCGNGWACE HRWRQIYNMV GFRNAVRGTG
410 420 430 440 450
INDWWSNGNQ QIAFCRGGSG FVAFNLEGYD MNENLQTCLS AGTYCDVISG
460 470 480
SKEGGSLVLQ CKSVEMDVPI SIFRPKVMMV FWPSM
Length:485
Mass (Da):54,133
Last modified:July 25, 2006 - v1
Checksum:iDFE3F354E8356130
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477511 Genomic DNA. Translation: EAT39767.1.
RefSeqiXP_001653282.1. XM_001653232.2.

Genome annotation databases

EnsemblMetazoaiAAEL008451-RA; AAEL008451-PA; AAEL008451.
GeneIDi5570646.
KEGGiaag:AaeL_AAEL008451.
VectorBaseiAAEL008451-RA; AAEL008451-PA; AAEL008451.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477511 Genomic DNA. Translation: EAT39767.1.
RefSeqiXP_001653282.1. XM_001653232.2.

3D structure databases

ProteinModelPortaliQ16YR2.
SMRiQ16YR2. Positions 21-456.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7159.AAEL008451-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAAEL008451-RA; AAEL008451-PA; AAEL008451.
GeneIDi5570646.
KEGGiaag:AaeL_AAEL008451.
VectorBaseiAAEL008451-RA; AAEL008451-PA; AAEL008451.

Phylogenomic databases

eggNOGiKOG2212. Eukaryota.
COG0366. LUCA.
InParanoidiQ16YR2.
KOiK01176.
OMAiWCIVAGQ.
OrthoDBiEOG091G07V6.
PhylomeDBiQ16YR2.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase/branching_C.
IPR031319. A-amylase_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013780. Glyco_hydro_b.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ16YR2_AEDAE
AccessioniPrimary (citable) accession number: Q16YR2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: September 7, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.