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Protein
Submitted name:

AAEL009310-PA

Gene

AAEL009310

Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Protein has several cofactor binding sites:
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 2 Zn2+ ions per subunit.UniRule annotation

GO - Molecular functioni

  1. carboxypeptidase activity Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. metallopeptidase activity Source: UniProtKB-KW
  4. peptidyl-dipeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

CarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.005.

Names & Taxonomyi

Protein namesi
Submitted name:
AAEL009310-PAImported
Gene namesi
ORF Names:AAEL009310Imported
OrganismiAedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported
Taxonomic identifieri7159 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia
ProteomesiUP000008820: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

GlycoproteinUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi7159.AAEL009310-PA.

Structurei

3D structure databases

ProteinModelPortaliQ16W80.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Phylogenomic databases

eggNOGiNOG71044.
HOGENOMiHOG000201754.
InParanoidiQ16W80.
KOiK01283.
OMAiYITDDTE.
OrthoDBiEOG76HQ13.
PhylomeDBiQ16W80.

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 1 hit.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Fragment.

Q16W80-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
LCHRAASLPQ VVVTNDVLNE EQMKQILQQY DTEVRSYCNR QVQANWNVAT
60 70 80 90 100
NTENTTFQEE QNKISLEYAK FRTDFYEQYF KDAQVQNYED PKVRKQLTLL
110 120 130 140 150
KDLGTAALPT SDLEEYNKVM RRMDAAYQLA EVCPYTDQNC APDAEKWTLD
160 170 180 190 200
PEMEHVMASS NDYDELTYTW RRWREESGKK MRQDYKLYVD YVNQAAKLNG
210 220 230 240 250
YADYGEMWRA RYDDSDLRGT LERLWKEVEP LYNELHTYVR FKLLDMYGDK
260 270 280 290 300
MDRNNEKIPA HILGNMWAQS WVNLYDRIKP FPDASLVDVT AKMQELGFNA
310 320 330 340 350
TKMFEMSDEF YQSLGLPSSA MSYGPKAVIE KQPQKMVCHA SAWDFCDGED
360 370 380 390 400
FRVKMCTNIN MEDFITVHHE MGHIMYFILY KDQPQLFKTG ATPAFHEAVG
410 420 430 440 450
DTIALSVATP KHLKLVGLLD EYADSEADNI NALFEMALER VAFLPFGYLI
460 470 480 490 500
DQWRWDVFSG AVNESEWNSH WWNLREKYQK VYAPVSRSES DFDPGAKYHI
510 520 530 540 550
PANSQYIAYF LAHILEFQFY RSLCIEAGEY NPSSSSANPL HKCDFYNSKA
560 570 580 590 600
AGNKLKEGLS LGYSEDWRFA LEKLTGGQDI SGHALLEYFA PLYEFLKEEN

AK
Length:602
Mass (Da):70,135
Last modified:July 25, 2006 - v1
Checksum:iB0AB9183B283BDE8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei602 – 6021Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477573 Genomic DNA. Translation: EAT38830.1.
RefSeqiXP_001659916.1. XM_001659866.1.

Genome annotation databases

EnsemblMetazoaiAAEL009310-RA; AAEL009310-PA; AAEL009310.
GeneIDi5571787.
KEGGiaag:AaeL_AAEL009310.
VectorBaseiAAEL009310. Aedes aegypti.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477573 Genomic DNA. Translation: EAT38830.1.
RefSeqiXP_001659916.1. XM_001659866.1.

3D structure databases

ProteinModelPortaliQ16W80.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7159.AAEL009310-PA.

Protein family/group databases

MEROPSiM02.005.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAAEL009310-RA; AAEL009310-PA; AAEL009310.
GeneIDi5571787.
KEGGiaag:AaeL_AAEL009310.
VectorBaseiAAEL009310. Aedes aegypti.

Phylogenomic databases

eggNOGiNOG71044.
HOGENOMiHOG000201754.
InParanoidiQ16W80.
KOiK01283.
OMAiYITDDTE.
OrthoDBiEOG76HQ13.
PhylomeDBiQ16W80.

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 1 hit.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Aedes aegypti, a major arbovirus vector."
    Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J., Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.
    , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.
    Science 316:1718-1723(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LVPib12Imported.

Entry informationi

Entry nameiQ16W80_AEDAE
AccessioniPrimary (citable) accession number: Q16W80
Entry historyi
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: January 7, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.