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Protein

Succinate dehydrogenase (quinone)

Gene

AAEL010608

Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Succinate + a quinone = fumarate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Electron transportUniRule annotation, Transport, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

FADUniRule annotation, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase (quinone)UniRule annotation (EC:1.3.5.1UniRule annotation)
Gene namesi
ORF Names:AAEL010608Imported
OrganismiAedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported
Taxonomic identifieri7159 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia
ProteomesiUP000008820 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

MembraneUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi7159.AAEL010608-PA.

Structurei

3D structure databases

ProteinModelPortaliQ16SE4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG1053.
HOGENOMiHOG000160475.
InParanoidiQ16SE4.
KOiK00234.
OMAiKWRTCFT.
OrthoDBiEOG7MH0XJ.
PhylomeDBiQ16SE4.

Family and domain databases

Gene3Di1.20.58.100. 1 hit.
3.90.700.10. 1 hit.
InterProiIPR003953. FAD_bind_dom.
IPR003952. FRD_SDH_FAD_BS.
IPR015939. Fum_Rdtase/Succ_DH_flav-like_C.
IPR027477. Succ_DH/fumarate_Rdtase_cat.
IPR011281. Succ_DH_flav_su_fwd.
IPR014006. Succ_Dhase_FrdA_Gneg.
[Graphical view]
PfamiPF00890. FAD_binding_2. 1 hit.
PF02910. Succ_DH_flav_C. 1 hit.
[Graphical view]
SUPFAMiSSF46977. SSF46977. 1 hit.
SSF56425. SSF56425. 1 hit.
TIGRFAMsiTIGR01816. sdhA_forward. 1 hit.
TIGR01812. sdhA_frdA_Gneg. 1 hit.
PROSITEiPS00504. FRD_SDH_FAD_BINDING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q16SE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SEMLRLPSLM AKSALSAARG LSAATSTQRG LHFTVGQNNA KTNPGAISKE
60 70 80 90 100
YPVVDHTYDA VVVGAGGAGL RAAFGLVAEG FKTAVITKLF PTRSHTVAAQ
110 120 130 140 150
GGINAALGNM EEDDWKWHMY DTVKGSDWLG DQDAIHYMTR EAPKAVIELE
160 170 180 190 200
NYGMPFSRTP DGKIYQRAFG GQSLKYGKGG QAHRCCCVAD RTGHSLLHTL
210 220 230 240 250
YGQSLSYDCN YFIEYFALDL LMENGQCVGV IALNLEDGSI HRFRSKNTVL
260 270 280 290 300
ATGGYGRAYF SCTSAHTCTG DGTAMVARAG LPSEDLEFVQ FHPTGIYGAG
310 320 330 340 350
CLITEGCRGE GGYLINSQGE RFMERYAPVA KDLASRDVVS RSMTIEIREG
360 370 380 390 400
RGCPEKDHVY LQLHHLPPEQ LAQRLPGISE TAMIFAGVDV TREPIPVLPT
410 420 430 440 450
VHYNMGGVPT NYKGQVLTVD SSGNDHVVPG LYACGESACS SVHGANRLGA
460 470 480 490 500
NSLLDLVVFG RACAKTIAAE NRPGEKIADI KPNAGEASVA NLDWVRNANG
510 520 530 540 550
AVPTSTLRLN MQKTMQTHAA VFREEKTLQE GVRKMADIYK TIKDVKVSDR
560 570 580 590 600
SLVWNSDLVE TLELQNLLLN ANMTITAAEN RKESRGAHAR EDYKHRVDEY
610 620 630 640 650
DYSKPLEGQQ KKPVEEHWRK HTLTWIDPET GAVKIDYRPV IDQTLSEECN

TVPPAIRSY
Length:659
Mass (Da):72,054
Last modified:July 25, 2006 - v1
Checksum:i32A21AA0A4E49E23
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477675 Genomic DNA. Translation: EAT37381.1.
RefSeqiXP_001660946.1. XM_001660896.2.

Genome annotation databases

EnsemblMetazoaiAAEL010608-RA; AAEL010608-PA; AAEL010608.
GeneIDi5573622.
KEGGiaag:AaeL_AAEL010608.
VectorBaseiAAEL010608. Aedes aegypti.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477675 Genomic DNA. Translation: EAT37381.1.
RefSeqiXP_001660946.1. XM_001660896.2.

3D structure databases

ProteinModelPortaliQ16SE4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7159.AAEL010608-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAAEL010608-RA; AAEL010608-PA; AAEL010608.
GeneIDi5573622.
KEGGiaag:AaeL_AAEL010608.
VectorBaseiAAEL010608. Aedes aegypti.

Phylogenomic databases

eggNOGiCOG1053.
HOGENOMiHOG000160475.
InParanoidiQ16SE4.
KOiK00234.
OMAiKWRTCFT.
OrthoDBiEOG7MH0XJ.
PhylomeDBiQ16SE4.

Family and domain databases

Gene3Di1.20.58.100. 1 hit.
3.90.700.10. 1 hit.
InterProiIPR003953. FAD_bind_dom.
IPR003952. FRD_SDH_FAD_BS.
IPR015939. Fum_Rdtase/Succ_DH_flav-like_C.
IPR027477. Succ_DH/fumarate_Rdtase_cat.
IPR011281. Succ_DH_flav_su_fwd.
IPR014006. Succ_Dhase_FrdA_Gneg.
[Graphical view]
PfamiPF00890. FAD_binding_2. 1 hit.
PF02910. Succ_DH_flav_C. 1 hit.
[Graphical view]
SUPFAMiSSF46977. SSF46977. 1 hit.
SSF56425. SSF56425. 1 hit.
TIGRFAMsiTIGR01816. sdhA_forward. 1 hit.
TIGR01812. sdhA_frdA_Gneg. 1 hit.
PROSITEiPS00504. FRD_SDH_FAD_BINDING. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Aedes aegypti, a major arbovirus vector."
    Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J., Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.
    , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.
    Science 316:1718-1723(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LVPib12Imported.

Entry informationi

Entry nameiQ16SE4_AEDAE
AccessioniPrimary (citable) accession number: Q16SE4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: July 22, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.