Q16RX0 (Q16RX0_AEDAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
AAEL010807-PA EMBL EAT37179.1

Gene names

ORF Names:

AAEL010807

Organism

Aedes aegypti (Yellowfever mosquito) (Culex aegypti) [Reference proteome] EMBL EAT37179.1

Taxonomic identifier

7159 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicimorpha › Culicoidea › Culicidae › Culicinae › Aedini › Aedes › Stegomyia

Protein attributes

Sequence length	1670 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 Contains 1 post-SET domain. RuleBase RU004541 SAAS SAAS001214

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS003616
Molecular function	Methyltransferase RuleBase RU004541 SAAS SAAS001214 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	histone lysine methylation Inferred from electronic annotation. Source: GOC
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q16RX0 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: C4C08B688C26C4D5	FASTA	1,670	185,956
	10 20 30 40 50 60 MNGTYDGKST SSSSSSSSGG GGGGGGGGGG GGTSSSHSQH KAPRNYKLIV DPLIHKGGVP 70 80 90 100 110 120 KIYRYDGIVP GDPTYPPVIP RDPRNPLARL RSRIEPFVMI VPRFKIDEHY IGEPPAIEIT 130 140 150 160 170 180 ITNLNDNIDK PFLSDLLAKC GTYTELYIYY HPITNKHLGI ARIVFENVRS ARICVERLNG 190 200 210 220 230 240 TSVMGKVLNV FKDPFGEECK RLIEDKSSEK KKPAPPPPLP PVPVHKAAPM IPAKPHPPPM 250 260 270 280 290 300 PPASSSSSHY GGRNSSGTEF DMWDVDEYSG SAGNSRDSFS YGKDKYSSAS KSGSQYESTR 310 320 330 340 350 360 EEDSRSRDKS RDKYYDRKDR DKPYFKDDRR DRERDRDRDR DYDRGRDRDR ERERDRDRER 370 380 390 400 410 420 DRDRDRDRDR DRDREWDRDR TRDRDREWDS RERDRYGRDR DRRRSKSGAY GWYGESGSYS 430 440 450 460 470 480 SDMSYGSSRY SQYDYSYGYG ASDYGTYGYP PPPSAIAGAS SYAASSSSWA PPPPPEEKPK 490 500 510 520 530 540 APPPPPTAKP NFSGKSNLGG QSVLDDSDMW DLEESSETAP KPPSTPPGPP EPKTEPAAED 550 560 570 580 590 600 DNSGSALDLD TRIALMFKDK TFGGAPFLQL SDAEEEEKKE EGETGDESQD VPIKQEEVQV 610 620 630 640 650 660 KKEIKLEPPK EEMASDISSS EDDILAKESP PPAPAKPYME DIIKRDNDQM SLSSLSSTDG 670 680 690 700 710 720 KNDDSKAPPL PADPVPDAPP PPEPTDSFAY VYPPGIGPGM GYPPAPPGTD PSYYYSQTYS 730 740 750 760 770 780 QASYQQYQSG YYQNSYMHPY MAGFTGAAYP YQKRDRYEDA IAAVIERVTA ELKQILKKDF 790 800 810 820 830 840 NKKMIENTAY KKYEAWWDEE ELKSKGKNKD ILNDITPLAV AKVDKAPDIN QLLNQNYDNL 850 860 870 880 890 900 DSNSSYIGLG LRATIPKMPS FRRIRKQPSP VPQDEDSRRS DQEDMVHGSD SEKETDFQPN 910 920 930 940 950 960 SSQTKAKTPP PSGSSATAVP VSRTSSASAV SRTEKRKPSV SSFFTSSSEE ESSASESEDS 970 980 990 1000 1010 1020 SESASLTDVE MSYTSRKQTP TSLRDKRDKR IYSDSDTDDD LDHPSSKFSL PSSSAGSRNK 1030 1040 1050 1060 1070 1080 AKIYSDSDSD EPSKPPRKEI LPPVSTEKAR SRSPEGFIPV GSKDRGTTPP PPPTTQLEPA 1090 1100 1110 1120 1130 1140 VSMLPLDQLH EDLSPDVDES PPTQQPPRTP GRESPKKSLY ELDRIYSDSE EEREYQEKQR 1150 1160 1170 1180 1190 1200 RKAEYLEQIE REFQEEQARL APAFKCCFCT TTNGNWQESS EKASQIKGQG RKEGERYQRS 1210 1220 1230 1240 1250 1260 TTTCCSRTRD SSSSCGTASN SAACYRPYHH DFATPSSEDF FSADEDAARR AAKASPASSD 1270 1280 1290 1300 1310 1320 GGSSQASQVA LDHCYSLPPS ASPSSSSPHP QSDSYAPVAK SANKYAPSSD VLAHDHGYTN 1330 1340 1350 1360 1370 1380 NDDIIGSAIP GTPGASIPMQ EQDVIPSITM TPNASAQQSF IPVAKYYQRD IHSEMAILYD 1390 1400 1410 1420 1430 1440 FLTRGIDAED IQYIKQSYEL LLSDDANSYL LNATHWVDHC TTERSFVPPP AKKRKKDKES 1450 1460 1470 1480 1490 1500 VSDIKQHSTG SARTEGFYKI DPREKAKYKY HHLKGTAAAN HLNNIEIAKA ATKMQGLSRE 1510 1520 1530 1540 1550 1560 ARSNQRRLLT AFGASTESEL LKFNQLKFRK KQLKFAKSAI HDWGLFAMEP IAADEMVIEY 1570 1580 1590 1600 1610 1620 VGQMVRPSVA DLRETKYEAI GIGSSYLFRI DMETIIDATK CGNLARFINH SCNPNCYAKV 1630 1640 1650 1660 1670 ITIESEKKIV IYSKQAIGIN EEITYDYKFP LEDEKIPCLC GAQGCRGTLN

References

[1]

"Genome sequence of Aedes aegypti, a major arbovirus vector." Nene V., Wortman J.R., Lawson D., Haas B., Kodira C., Tu Z.J., Loftus B., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P. , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., Debruyn B., Decaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston J.S., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'leary S., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.H., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M., Vanzee J.P., Verjovski-Almeida S., Werner D., White O., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Birren B., Fraser-Liggett C.M., Severson D.W. Science 316:1718-1723(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LVPib12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH477694 Genomic DNA. Translation: EAT37179.1.
RefSeq	XP_001654916.1. XM_001654866.1.
UniGene	Aae.11218.
3D structure databases
ProteinModelPortal	Q16RX0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q16RX0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AAEL010807-RA; AAEL010807-PA; AAEL010807.
GeneID	5573880.
KEGG	aag:AaeL_AAEL010807.
VectorBase	AAEL010807. Aedes aegypti.
Phylogenomic databases
eggNOG	COG2940.
HOGENOM	HOG000047266.
KO	K11422.
OMA	HCYSLPP.
OrthoDB	EOG4P5HQZ.
PhylomeDB	Q16RX0.
Family and domain databases
Gene3D	3.30.70.330. 1 hit.
InterPro	IPR024657. COMPASS_Set1_N-SET. IPR015722. Histone-lysine_MeTfrase. IPR012677. Nucleotide-bd_a/b_plait. IPR003616. Post-SET_dom. IPR000504. RRM_dom. IPR001214. SET_dom. [Graphical view]
PANTHER	PTHR22884:SF10. PTHR22884:SF10. 1 hit.
Pfam	PF11764. N-SET. 1 hit. PF00076. RRM_1. 1 hit. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00508. PostSET. 1 hit. SM00360. RRM. 1 hit. SM00317. SET. 1 hit. [Graphical view]
PROSITE	PS50868. POST_SET. 1 hit. PS50102. RRM. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q16RX0_AEDAE

Accession

Primary (citable) accession number: Q16RX0

Entry history

Integrated into UniProtKB/TrEMBL:	July 25, 2006
Last sequence update:	July 25, 2006
Last modified:	March 6, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)