Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q16QZ8

- Q16QZ8_AEDAE

UniProt

Q16QZ8 - Q16QZ8_AEDAE

Protein

Histone deacetylase

Gene

AAEL011117

Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (25 Jul 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotation

    GO - Molecular functioni

    1. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: UniProtKB-EC
    2. NAD-dependent histone deacetylase activity (H3-K18 specific) Source: UniProtKB-EC
    3. NAD-dependent histone deacetylase activity (H3-K9 specific) Source: UniProtKB-EC
    4. NAD-dependent histone deacetylase activity (H4-K16 specific) Source: UniProtKB-EC

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulatorUniRule annotation, HydrolaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone deacetylaseUniRule annotation (EC:3.5.1.98UniRule annotation)
    Gene namesi
    ORF Names:AAEL011117Imported
    OrganismiAedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported
    Taxonomic identifieri7159 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia
    ProteomesiUP000008820: Unassembled WGS sequence

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    NucleusUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi7159.AAEL011117-PA.

    Structurei

    3D structure databases

    ProteinModelPortaliQ16QZ8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0123.
    HOGENOMiHOG000225180.
    KOiK11404.
    OMAiNFHYGPG.
    OrthoDBiEOG7DNNTW.
    PhylomeDBiQ16QZ8.

    Family and domain databases

    Gene3Di3.40.800.20. 1 hit.
    InterProiIPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSiPR01270. HDASUPER.
    PR01271. HISDACETLASE.

    Sequencei

    Sequence statusi: Complete.

    Q16QZ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSKKVSYFF NPDVGNFHYG PGHPMKPHRL SVIHHLVMNY GLHKKMQIYR    50
    PYKASAHDMC RFHSDEYIEF LQRVTPQNIQ GYTKCLSVFN VGDDCPVFDG 100
    LFEFCAMYTG ASLEGAQKLN HNHSDICINW SGGLHHAKKF EASGFCYVND 150
    IVIGILELLK YHPRVLYIDI DVHHGDGVQE AFYLTDRVMT VSFHKYGNYF 200
    FPGTGDMYEI GAESGRYYSV NVPLKEGIDD QSYVQVFKPV ISAVMEFYQP 250
    TAIVLQCGAD SLAGDRLGCF SLSTKGHGEC VKFVKDLNVP TLVVGGGGYT 300
    LRNVARCWTY ETSLLIDETI SNELPMNDYL EFFAPDFTLH PDIPSRQDNA 350
    NSKQYLEAIT RHVYDNLKMC QHAPSVQMFD IPEDALPEDV KVKDEPNPEA 400
    RMTQDEEDKQ VEPKNEFFDG ENDNDKSENE P 431
    Length:431
    Mass (Da):49,008
    Last modified:July 25, 2006 - v1
    Checksum:i19C709A4B1EB4EA7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH477727 Genomic DNA. Translation: EAT36822.1.
    RefSeqiXP_001655108.1. XM_001655058.1.
    UniGeneiAae.2843.

    Genome annotation databases

    EnsemblMetazoaiAAEL011117-RA; AAEL011117-PA; AAEL011117.
    GeneIDi5574401.
    KEGGiaag:AaeL_AAEL011117.
    VectorBaseiAAEL011117. Aedes aegypti.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH477727 Genomic DNA. Translation: EAT36822.1 .
    RefSeqi XP_001655108.1. XM_001655058.1.
    UniGenei Aae.2843.

    3D structure databases

    ProteinModelPortali Q16QZ8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7159.AAEL011117-PA.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai AAEL011117-RA ; AAEL011117-PA ; AAEL011117 .
    GeneIDi 5574401.
    KEGGi aag:AaeL_AAEL011117.
    VectorBasei AAEL011117. Aedes aegypti.

    Phylogenomic databases

    eggNOGi COG0123.
    HOGENOMi HOG000225180.
    KOi K11404.
    OMAi NFHYGPG.
    OrthoDBi EOG7DNNTW.
    PhylomeDBi Q16QZ8.

    Family and domain databases

    Gene3Di 3.40.800.20. 1 hit.
    InterProi IPR000286. His_deacetylse.
    IPR003084. His_deacetylse_1.
    IPR023801. His_deacetylse_dom.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037913. His_deacetylse_1. 1 hit.
    PRINTSi PR01270. HDASUPER.
    PR01271. HISDACETLASE.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Aedes aegypti, a major arbovirus vector."
      Nene V., Wortman J.R., Lawson D., Haas B., Kodira C., Tu Z.J., Loftus B., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.
      , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., Debruyn B., Decaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston J.S., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'leary S., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.H., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M., Vanzee J.P., Verjovski-Almeida S., Werner D., White O., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Birren B., Fraser-Liggett C.M., Severson D.W.
      Science 316:1718-1723(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LVPib12Imported.

    Entry informationi

    Entry nameiQ16QZ8_AEDAE
    AccessioniPrimary (citable) accession number: Q16QZ8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 25, 2006
    Last sequence update: July 25, 2006
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3