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Protein

PBAN-type neuropeptides

Gene

PBAN

Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

A hormone that controls sex pheromone production in females and pheromone responsiveness in male. Also mediates visceral muscle contractile activity (myotropic activity) (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHormone, Neuropeptide

Names & Taxonomyi

Protein namesi
Recommended name:
PBAN-type neuropeptides
Alternative name(s):
Pheromone/pyrokinin biosynthesis-activating neuropeptide
Cleaved into the following 4 chains:
Alternative name(s):
Pyrokinin-1
Alternative name(s):
Pyrokinin-2
Alternative name(s):
Pyrokinin-3
Gene namesi
Name:PBANBy similarity
ORF Names:AAEL012060
OrganismiAedes aegypti (Yellowfever mosquito) (Culex aegypti)
Taxonomic identifieri7159 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia
Proteomesi
  • UP000008820 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
PropeptideiPRO_000033925123 – 47Sequence analysisBy similarityAdd BLAST25
PeptideiPRO_000033925250 – 59AAAMWFGPRL-amideBy similarity10
PropeptideiPRO_000033925363 – 111By similarityAdd BLAST49
PeptideiPRO_0000339254113 – 126QPQPVFYHSTTPRL-amideBy similarityAdd BLAST14
PeptideiPRO_0000339255130 – 147DASSSNENNSRPPFAPRL-amideBy similarityAdd BLAST18
PeptideiPRO_0000339256150 – 157NLPFSPRL-amideBy similarity8
PropeptideiPRO_0000339257160 – 171By similarityAdd BLAST12

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei59Leucine amideBy similarity1
Modified residuei126Leucine amideBy similarity1
Modified residuei147Leucine amideBy similarity1
Modified residuei157Leucine amideBy similarity1

Keywords - PTMi

Amidation, Cleavage on pair of basic residues

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7159.AAEL012060-PA.

Structurei

3D structure databases

ProteinModelPortaliQ16N80.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pyrokinin family.Sequence analysis

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000045417.
InParanoidiQ16N80.
OMAiKRAAAMW.
OrthoDBiEOG091G0W16.
PhylomeDBiQ16N80.

Family and domain databases

InterProiView protein in InterPro
IPR008730. PBAN.
IPR001484. Pyrokinin_CS.
PfamiView protein in Pfam
PF05874. PBAN. 1 hit.
PROSITEiView protein in PROSITE
PS00539. PYROKININ. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q16N80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRLYFFFNV ICIFLAIRSA IGGEVPDATE QKINNFLASG KDSEDLSKRA
60 70 80 90 100
AAMWFGPRLG KRTIASELHD EMMDEIDDNP LYYSGESPQR VASEIAQGTP
110 120 130 140 150
YVVLLLTGRV LRQPQPVFYH STTPRLGRRD ASSSNENNSR PPFAPRLGRN
160 170
LPFSPRLGRS FGAPVVDNFA Y
Length:171
Mass (Da):19,176
Last modified:July 25, 2006 - v1
Checksum:iB063018DC5D9EACB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH477835 Genomic DNA. Translation: EAT35796.1.
RefSeqiXP_001662212.1. XM_001662162.1.

Genome annotation databases

EnsemblMetazoaiAAEL012060-RA; AAEL012060-PA; AAEL012060.
GeneIDi5575794.
KEGGiaag:AaeL_AAEL012060.
VectorBaseiAAEL012060-RA; AAEL012060-PA; AAEL012060.

Similar proteinsi

Entry informationi

Entry nameiPBAN_AEDAE
AccessioniPrimary (citable) accession number: Q16N80
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: July 25, 2006
Last modified: November 22, 2017
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families