Q16LE8 (Q16LE8_AEDAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate isomerase RuleBase RU000612
EC=5.3.1.9 RuleBase RU000612

Gene names

ORF Names:

AAEL012665, AaeL_AAEL012665 EMBL EAT35150.1

Organism

Aedes aegypti (Yellowfever mosquito) (Culex aegypti)

Taxonomic identifier

7159 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicoidea › Culicidae › Culicinae › Aedini › Aedes › Stegomyia

Protein attributes

Sequence length	416 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. RuleBase RU000612
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. RuleBase RU000612
Subcellular location	Cytoplasm By similarity RuleBase RU003642.
Sequence similarities	Belongs to the GPI family. RuleBase RU000612

Ontologies

Keywords
Biological process	Gluconeogenesis RuleBase RU000612 Glycolysis RuleBase RU000612
Molecular function	Isomerase RuleBase RU000612 EMBL EAT35150.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: UniProtKB-KW glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q16LE8 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: 4BB46625938F6695	FASTA	416	46,948
	10 20 30 40 50 60 MSNKVLLSED SVYQQIQQYY KEHGASINIK KIFQEDDIRF DKFSLKLNTP KDGEILLDYS 70 80 90 100 110 120 KNRITDEAWN MLLELAESRD VVKTRNDMFN GERINITENR AVLHIALRNR SNKPIMVDGK 130 140 150 160 170 180 DVMPEVNGVL EHMKEFTEQV LNGVWRGYTN KKISDVVNIG IGGSDLGPLM VSEALKAYNT 190 200 210 220 230 240 GIRSHFVSNV DGTHIAETLK KLDPETTLFI IASKTFTTQE TITNATAAKR WFLERCGEQE 250 260 270 280 290 300 HVAKHFVALS TNKEKVAAFG INTKNMFEFW DWVGGRYSLW SAIGLSISLA IGFDNFEKLL 310 320 330 340 350 360 DGAHYMDNHF LNAPLNENAP VILALMGIWY SNFYGAETHA LLPYDQYLHR FAAYFQQGDM 370 380 390 400 410 ESNGKGVTKA GKRVNFNTGP IVWGEPGTNG QHAFYQLIHQ VSAIGDTCIT VKCVAQ

References

[1]

"Genome sequence of Aedes aegypti, a major arbovirus vector." Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J., Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P. , Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L., Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J., Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H., Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J., Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W., Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R., Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T., Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W. Science 316:1718-1723(2007) [PubMed: 17510324] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LVPib12.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH477908 Genomic DNA. Translation: EAT35150.1.
RefSeq	XP_001662803.1. XM_001662753.1.
UniGene	Aae.26310. Aae.2989.
3D structure databases
ProteinModelPortal	Q16LE8.
SMR	Q16LE8. Positions 7-400.
ModBase	Search...
Protein-protein interaction databases
STRING	Q16LE8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AAEL012665-RA; AAEL012665-PA; AAEL012665.
GeneID	5576641.
KEGG	aag:AaeL_AAEL012665.
VectorBase	AAEL012665. Aedes aegypti.
Phylogenomic databases
GeneTree	EMGT00050000016728.
OMA	NDFLKGA.
OrthoDB	EOG4JSXMP.
PhylomeDB	Q16LE8.
Family and domain databases
HAMAP	MF_00473. G6P_isomerase. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q16LE8_AEDAE

Accession

Primary (citable) accession number: Q16LE8

Entry history

Integrated into UniProtKB/TrEMBL:	July 25, 2006
Last sequence update:	July 25, 2006
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)