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Q16DK2 (Q16DK2_ROSDO) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length804 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. HAMAP MF_01898

Catalytic activity

ATP-dependent breakage, passage and rejoining of double-stranded DNA. SAAS SAAS002288 HAMAP MF_01898

Subunit structure

Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01898

Subcellular location

Cytoplasm By similarity HAMAP MF_01898.

Sequence similarities

Belongs to the type II topoisomerase family. HAMAP MF_01898

Sequences

Sequence LengthMass (Da)Tools
Q16DK2 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: 1FCFF14B3619C4C0

FASTA80489,291
        10         20         30         40         50         60 
MSENDQTPEE YGANSIKVLK GLEAVRKRPG MYIGDTDDGS GLHHMVYEVV DNGIDEALAG 

        70         80         90        100        110        120 
HADAVTVKIH ADSSVSVSDN GRGIPVGIHE EEGVSAAEVI MTQLHAGGKF DSNSYKVSGG 

       130        140        150        160        170        180 
LHGVGVSVVN ALSDWLELRI WREGKEHVAR FEGGFTTRHL EVVGDTDRTG TEVRFMASTE 

       190        200        210        220        230        240 
TFSNLDYSFE TLEKRLRELA FLNSGVRIIL IDERPAEELR SDLFYEGGVK EFVKYLDRSK 

       250        260        270        280        290        300 
SSVMPEPIFI TGEKDDIGVE VAMWWNDSYH ENVLPFTNNI PQRDGGTHMA GFRGALTRTI 

       310        320        330        340        350        360 
NNYAQSSGIA RKEKVSFTGD DAREGLTCVL SVKVPDPKFS SQTKDKLVSS EVRPAVEGLV 

       370        380        390        400        410        420 
NEKLAEWFEE NPAEAKIVVG KIIEAAHARE AARKARDLTR RKTAMDVNFL AGKLKDCSEK 

       430        440        450        460        470        480 
DPSKTEVFLV EGDSAGGSAQ TGRDRQTQAI LPLKGKILNV ERARFDRMLG SQEIGNLVMA 

       490        500        510        520        530        540 
LGTGIGRDEF NIDKLRYHKI VIMTDADVDG AHIRTLLLTF FYRQMPQLIE QGHLYIAQPP 

       550        560        570        580        590        600 
LYKVSRGKSE VYLKDEAAME EYLIQQGIDG AMLRQGNNEE ISGADLARVV ELARQMRRVL 

       610        620        630        640        650        660 
DAFPTHYPRH ILEQAAIAGA FTPGAVDADL QGVADKVAAR LNLIALEYER GWQGRITQDH 

       670        680        690        700        710        720 
GIRLARILRG VEEVRTLDGR ILRGGEASRS GSFTEHLQEV YNLPATLVRK DRTQLIHGPM 

       730        740        750        760        770        780 
DLLNAILQEG EKGLSLQRYK GLGEMNPDQL WETTLDPDAR TLLQVKVDDM AEADDLFTKL 

       790        800 
MGDVVEPRRE FIQQNALSVE NLDF

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References

[1]"The complete genome sequence of Roseobacter denitrificans reveals a mixotrophic rather than photosynthetic metabolism."
Swingley W.D., Sadekar S., Mastrian S.D., Matthies H.J., Hao J., Ramos H., Acharya C.R., Conrad A.L., Taylor H.L., Dejesa L.C., Shah M.K., O'Huallachain M.E., Lince M.T., Blankenship R.E., Beatty J.T., Touchman J.W.
J. Bacteriol. 189:683-690(2007) [PubMed: 17098896] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000362 Genomic DNA. Translation: ABG29941.1.
RefSeqYP_680627.1. NC_008209.1.

3D structure databases

ProteinModelPortalQ16DK2.
SMRQ16DK2. Positions 16-384.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ16DK2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4198162.
GenomeReviewsGene locus RD1_0212 in contig CP000362_GR.
KEGGrde:RD1_0212.
NMPDRfig|375451.6.peg.199.
PATRIC23358603. VBIRosDen86677_0206.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0187.
HOGENOMHBG304889.
OMADCSSRDP.
PhylomeDBQ16DK2.
ProtClustDBPRK14939.

Enzyme and pathway databases

BioCycRDEN375451:RD1_0212-MONOMER.

Family and domain databases

HAMAPMF_01898. GyrB.
[Tree]
InterProIPR003594. ATPase-like_ATP-bd.
IPR011557. GyrB.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR001241. Topo_IIA.
IPR013759. Topo_IIA_B/N_ab.
IPR002288. Topo_IIA_B_C.
IPR013506. Topo_IIA_bsu_dom2.
IPR013760. Topo_IIA_cen.
IPR018522. TopoIIA_CS.
[Graphical view]
Gene3DG3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit.
G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KOK02470.
PfamPF00204. DNA_gyraseB. 1 hit.
PF00986. DNA_gyraseB_C. 1 hit.
PF02518. HATPase_c. 1 hit.
[Graphical view]
PRINTSPR00418. TPI2FAMILY.
SMARTSM00387. HATPase_c. 1 hit.
SM00433. TOP2c. 1 hit.
[Graphical view]
SUPFAMSSF55874. ATP_bd_ATPase. 1 hit.
SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMsTIGR01059. GyrB. 1 hit.
PROSITEPS00177. TOPOISOMERASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ16DK2_ROSDO
AccessionPrimary (citable) accession number: Q16DK2
Entry history
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info