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Q16D26 (Q16D26_ROSDO) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:RD1_0401
OrganismRoseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans) [Complete proteome] [HAMAP] EMBL ABG30117.1
Taxonomic identifier375451 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Roseobacter

Protein attributes

Sequence length347 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323

Ontologies

Keywords
   Biological processHeme biosynthesis HAMAP MF_00323
Porphyrin biosynthesis HAMAP MF_00323
   Cellular componentCytoplasm HAMAP MF_00323
   LigandIron HAMAP MF_00323
Metal-binding HAMAP MF_00323
   Molecular functionLyase HAMAP MF_00323 EMBL ABG30117.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processheme biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionferrochelatase activity

Inferred from electronic annotation. Source: HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2151Iron By similarity HAMAP MF_00323
Metal binding2961Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
Q16D26 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: 2C4D8153C72B9216

FASTA34739,509
        10         20         30         40         50         60 
MARPTHAESD HPEVAKPKVG ILLANLGTPD NYDYWSMRRY LNEFLSDRRV IDYSPWIWQP 

        70         80         90        100        110        120 
LLQLIILSKR PFSSGAAYKS IWNEEDGESP LMTITKAQTK KVKEVMAQRH GDEVMVDFCM 

       130        140        150        160        170        180 
RYGNPSTRSK VAAMTAAGCR KILFFPLYPH YAGATSATAN DEFFRSLTYE KWQPTTRTVD 

       190        200        210        220        230        240 
PYFDRPDYIE ALAQSIERAY AGMVTKPDIL VCSYHGVPIR YLMEGDPYHC QCQKTTRLLK 

       250        260        270        280        290        300 
ERLGWADTEI TTTFQSKFGP EEWLQPYTVE EVARLAEAGK KNIAVCAPAF SADCIETLEE 

       310        320        330        340 
INEEIKESFE EAGGEQFTYI PCLNDDDAHI AALCNTIDDN LKGWVDT

« Hide

References

[1]"The complete genome sequence of Roseobacter denitrificans reveals a mixotrophic rather than photosynthetic metabolism."
Swingley W.D., Sadekar S., Mastrian S.D., Matthies H.J., Hao J., Ramos H., Acharya C.R., Conrad A.L., Taylor H.L., Dejesa L.C., Shah M.K., O'Huallachain M.E., Lince M.T., Blankenship R.E., Beatty J.T., Touchman J.W.
J. Bacteriol. 189:683-690(2007) [PubMed: 17098896] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000362 Genomic DNA. Translation: ABG30117.1.
RefSeqYP_680803.1. NC_008209.1.

3D structure databases

ProteinModelPortalQ16D26.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ16D26.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4195388.
GenomeReviewsGene locus RD1_0401 in contig CP000362_GR.
KEGGrde:RD1_0401.
NMPDRfig|375451.6.peg.376.
PATRIC23358977. VBIRosDen86677_0392.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
PhylomeDBQ16D26.
ProtClustDBPRK00035.

Enzyme and pathway databases

BioCycRDEN375451:RD1_0401-MONOMER.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ16D26_ROSDO
AccessionPrimary (citable) accession number: Q16D26
Entry history
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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