Q169Q7 (Q169Q7_ROSDO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2-dehydro-3-deoxyphosphooctonate aldolase HAMAP MF_00056
EC=2.5.1.55 HAMAP MF_00056

Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase HAMAP MF_00056
KDO-8-phosphate synthase HAMAP MF_00056
Phospho-2-dehydro-3-deoxyoctonate aldolase HAMAP MF_00056

Gene names

Name:	kdsA HAMAP MF_00056
Ordered Locus Names:	RD1_1661

Organism

Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans) [Complete proteome] [HAMAP] EMBL ABG31286.1

Taxonomic identifier

375451 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Roseobacter

Protein attributes

Sequence length	277 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. HAMAP MF_00056
Pathway	Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP MF_00056 Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. HAMAP MF_00056
Subcellular location	Cytoplasm By similarity HAMAP MF_00056.
Sequence similarities	Belongs to the KdsA family. HAMAP MF_00056

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis HAMAP MF_00056
Cellular component	Cytoplasm HAMAP MF_00056
Molecular function	Transferase HAMAP MF_00056 EMBL ABG31286.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-deoxy-8-phosphooctulonate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q169Q7 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: F14292CC52940FDC	FASTA	277	29,292
	10 20 30 40 50 60 MTHVPVGDLV IGNDRPLTVI AGPCQLESAD HAQMIAGRMK EACDKAGAQY VFKASYDKAN 70 80 90 100 110 120 RTSLSGIRGP GMDEGLKILQ SVGQAIDVPV LTDVHNEGQC APAAQAVDIL QIPAFLCRQT 130 140 150 160 170 180 DMLLAAGQTG AAVNVKKGQF LAPWEMSNIT TKIESTGNTR ILLTERGTSF GYNTLVADMR 190 200 210 220 230 240 ALPQMAQTGY PVVMDATHSV QQPGGKGGSS GGQREFAPVM ARAAVAIGVA AVFIETHENP 250 260 270 DASPSDGPNM IYLDQMPDLI ETLMQFDALA KARPVVI

References

[1]

"The complete genome sequence of Roseobacter denitrificans reveals a mixotrophic rather than photosynthetic metabolism." Swingley W.D., Sadekar S., Mastrian S.D., Matthies H.J., Hao J., Ramos H., Acharya C.R., Conrad A.L., Taylor H.L., Dejesa L.C., Shah M.K., O'Huallachain M.E., Lince M.T., Blankenship R.E., Beatty J.T., Touchman J.W. J. Bacteriol. 189:683-690(2007) [PubMed: 17098896] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000362 Genomic DNA. Translation: ABG31286.1.
RefSeq	YP_681972.1. NC_008209.1.
3D structure databases
ProteinModelPortal	Q169Q7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q169Q7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4197075.
GenomeReviews	Gene locus RD1_1661 in contig CP000362_GR.
KEGG	rde:RD1_1661.
NMPDR	fig|375451.6.peg.1555.
PATRIC	23361419. VBIRosDen86677_1600.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2877.
HOGENOM	HBG575990.
OMA	FLETHED.
PhylomeDB	Q169Q7.
ProtClustDB	PRK05198.
Enzyme and pathway databases
BioCyc	RDEN375451:RD1_1661-MONOMER.
Family and domain databases
HAMAP	MF_00056. KDO8P_synth. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR006218. DAHP1/KDSA. IPR006269. KDO8P_synthase. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01627.
PANTHER	PTHR21057:SF2. KDO8P_synthase. 1 hit.
Pfam	PF00793. DAHP_synth_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR01362. KDO8P_synth. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q169Q7_ROSDO

Accession

Primary (citable) accession number: Q169Q7

Entry history

Integrated into UniProtKB/TrEMBL:	July 25, 2006
Last sequence update:	July 25, 2006
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)