Unreviewed, UniProtKB/TrEMBL Q16938 (Q16938_ANCCA)

Names and origin

Protein names	Submitted name:     Anti-coagulant protein C2 EMBL AAC47080.1
Organism	Ancylostoma caninum (Dog hookworm) EMBL AAC47080.1
Taxonomic identifier	29170 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Nematoda › Chromadorea › Rhabditida › Strongylida › Ancylostomatoidea › Ancylostomatidae › Ancylostomatinae › Ancylostoma

Protein attributes

Sequence length	91 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Domain	Signal
Gene Ontology (GO)
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
F10	O88947	1	EBI-1646299,EBI-1646313	From a different organism.
F10	P00742	1	EBI-1646299,EBI-719750	From a different organism.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	‹1 – 7	›7	Potential EMBL AAC47080.1
	Chain	8 – 91	84	anti-coagulant protein C2 EMBL AAC47080.1		PRO_5000144647
Experimental info
	Non-terminal residue	1	1	EMBL AAC47080.1

Sequences

	Sequence		Length	Mass (Da)
	Q16938-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: ECB11CB4597C24DA	FASTA	91	10,358
	10 20 30 40 50 60 LVSYCSGKAT MQCGENEKYD SCGSKECDKK CKYDGVEEED DEEPNVPCLV RVCHQDCVCE 70 80 90 EGFYRNKDDK CVSAEDCELD NMDFIYPGTR N

References

[1]	"Surface expression and ligand-based selection of cDNAs fused to filamentous phage gene VI." Jespers L.S., Messens J.H., De Keyser A., Eeckhout D., Van den Brande I., Gansemans Y.G., Lauwereys M.J., Vlasuk G.P., Stanssens P.E. Biotechnology (N.Y.) 13:378-382(1995) [PubMed: 9634780] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Anticoagulant repertoire of the hookworm Ancylostoma caninum." Stassens P., Bergum P.W., Gansemans Y., Jespers L., Laroche Y., Huang S., Maki S., Messens J., Lauwereys M., Cappello M., Hotez P.J., Lasters I., Vlasuk G.P. Proc. Natl. Acad. Sci. U.S.A. 93:2149-2154(1996) [PubMed: 8700900] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Inherent flexibility in a potent inhibitor of blood coagulation, recombinant nematode anticoagulant protein c2." Duggan B.M., Dyson H.J., Wright P.E. Eur. J. Biochem. 265:539-548(1999) [PubMed: 10504384] [Abstract] Cited for: STRUCTURE BY NMR OF 8-91.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

U30793 mRNA. Translation: AAC47080.1.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1COU	NMR	-	A	8-91	[»]
2H9E	X-ray	2.20	C	8-91	[»]

ModBase

Search...

Protein-protein interaction databases

IntAct

Q16938. 2 interactions.

Protein family/group databases

MEROPS

I08.010.

Family and domain databases

InterPro

IPR013032. EGF-like_reg_CS.
IPR018453. Prot_Inh_CR_TIL_sg.
[Graphical view]

Pfam

PF01826. TIL. 1 hit.
[Graphical view]

PROSITE

PS01186. EGF_2. 1 hit. Uncertain.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q16938_ANCCA

Accession

Primary (citable) accession number: Q16938

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	June 16, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)