Q168G6 (Q168G6_ROSDO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Choline dehydrogenase EMBL ABG31627.1
EC=1.1.99.1 EMBL ABG31627.1

Gene names

Name:	betA EMBL ABG31627.1
Ordered Locus Names:	RD1_2024

Organism

Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans) [Complete proteome] [HAMAP] EMBL ABG31627.1

Taxonomic identifier

375451 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Roseobacter

Protein attributes

Sequence length	552 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. SAAS SAAS007867
Catalytic activity	Choline + acceptor = betaine aldehyde + reduced acceptor. SAAS SAAS007867
Cofactor	FAD By similarity. SAAS SAAS007867
Pathway	Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. SAAS SAAS007867

Ontologies

Keywords
Ligand	FAD SAAS SAAS011533 Flavoprotein SAAS SAAS011533
Molecular function	Oxidoreductase SAAS SAAS007867 EMBL ABG31627.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: InterPro
Molecular function	choline dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q168G6 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: BD777BFD01AF53F9	FASTA	552	60,468
	10 20 30 40 50 60 MQADFVIVGA GSAGCAMAYR LSEAGASVIV IEHGGTDAGP LIQMPAALSY PMNMKRYDWG 70 80 90 100 110 120 YSSEPEPHLG GRRLACPRGK VIGGSSSING MVYVRGHAMD FDHWAEQGAE GWSYADVLPY 130 140 150 160 170 180 YKRMENWHDG GHGGDPAWRG TDGPLHVSRG ARQNPLFKAF VQAGIEAGYQ ATDDYNGHKQ 190 200 210 220 230 240 EGFGPMEQTV WRGRRWSAAN AYLRPALKRD NCTLVNGLAQ RVIFEGRRAR GVEILQGGKT 250 260 270 280 290 300 KVIHAAREVV LAASSINSPK LLMLSGVGPA GHLAEQGVDV IADRPGVGQN LQDHLELYLQ 310 320 330 340 350 360 MASKQPITLY RYWNLFSKAV IGAQWLFTKT GMGSSNQFES AAFIRSKAGV PYPDVQYHFL 370 380 390 400 410 420 PIAVRYDGKV AAEGHGFQAH VGPMRSKSRG SVTLASPDPA EAPKITFNYM SHADDWEDFR 430 440 450 460 470 480 RCIRLTREIF AQDAFKPFVK HEIQPGAAVQ SDDALNDFIS EHVESAYHPC GTCRMGRADD 490 500 510 520 530 540 PQAVVDPQAR VIGVEGLRVA DSSIFPRITN GNLNAPSIMV GEKVSDHLLG KDTLARSNDR 550 AWIHPDWQTA QR

References

[1]

"The complete genome sequence of Roseobacter denitrificans reveals a mixotrophic rather than photosynthetic metabolism." Swingley W.D., Sadekar S., Mastrian S.D., Matthies H.J., Hao J., Ramos H., Acharya C.R., Conrad A.L., Taylor H.L., Dejesa L.C., Shah M.K., O'Huallachain M.E., Lince M.T., Blankenship R.E., Beatty J.T., Touchman J.W. J. Bacteriol. 189:683-690(2007) [PubMed: 17098896] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000362 Genomic DNA. Translation: ABG31627.1.
RefSeq	YP_682313.1. NC_008209.1.
3D structure databases
ProteinModelPortal	Q168G6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q168G6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4196691.
GenomeReviews	Gene locus RD1_2024 in contig CP000362_GR.
KEGG	rde:RD1_2024.
NMPDR	fig|375451.6.peg.1890.
PATRIC	23362117. VBIRosDen86677_1944.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2303.
HOGENOM	HBG734713.
OMA	GPFIQMP.
PhylomeDB	Q168G6.
ProtClustDB	PRK02106.
Enzyme and pathway databases
BioCyc	RDEN375451:RD1_2024-MONOMER.
Family and domain databases
InterPro	IPR011533. Choline_dehydrogenase. IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view]
KO	K00108.
Pfam	PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view]
PIRSF	PIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMs	TIGR01810. BetA. 1 hit.
PROSITE	PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q168G6_ROSDO

Accession

Primary (citable) accession number: Q168G6

Entry history

Integrated into UniProtKB/TrEMBL:	July 25, 2006
Last sequence update:	July 25, 2006
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)