##gff-version 3
Q16878	UniProtKB	Chain	1	200	.	.	.	ID=PRO_0000206606;Note=Cysteine dioxygenase type 1	
Q16878	UniProtKB	Binding site	86	86	.	.	.	Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17135237;Dbxref=PMID:17135237	
Q16878	UniProtKB	Binding site	88	88	.	.	.	Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17135237;Dbxref=PMID:17135237	
Q16878	UniProtKB	Binding site	140	140	.	.	.	Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17135237;Dbxref=PMID:17135237	
Q16878	UniProtKB	Cross-link	93	157	.	.	.	Note=3'-(S-cysteinyl)-tyrosine (Cys-Tyr);Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17135237;Dbxref=PMID:17135237	
Q16878	UniProtKB	Natural variant	45	45	.	.	.	ID=VAR_023536;Note=T->I;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:7524679,ECO:0000269|PubMed:9497919;Dbxref=dbSNP:rs1042867,PMID:7524679,PMID:9497919	
Q16878	UniProtKB	Natural variant	143	143	.	.	.	ID=VAR_036170;Note=In a colorectal cancer sample%3B somatic mutation. E->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16959974;Dbxref=PMID:16959974	
Q16878	UniProtKB	Mutagenesis	60	60	.	.	.	Note=Reduces enzyme activity by 70%25. Reduces iron and zinc incorporation by 50%25. R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17135237;Dbxref=PMID:17135237	
Q16878	UniProtKB	Mutagenesis	93	93	.	.	.	Note=Reduces enzyme activity and iron incorporation by 50%25. Zinc incorporation increased by 20%25. C->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17135237;Dbxref=PMID:17135237	
Q16878	UniProtKB	Mutagenesis	157	157	.	.	.	Note=Almost total loss of enzyme activity and iron incorporation. Reduces zinc incorporation by 20%25. Y->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17135237;Dbxref=PMID:17135237	
Q16878	UniProtKB	Mutagenesis	164	164	.	.	.	Note=Reduces enzyme activity by 20%25. Little effect on iron incorporation. No effect on zinc incorporation. C->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17135237;Dbxref=PMID:17135237	
Q16878	UniProtKB	Sequence conflict	137	137	.	.	.	Note=I->V;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q16878	UniProtKB	Helix	12	22	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	24	26	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Helix	30	39	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Helix	44	47	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Helix	48	50	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	55	57	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	59	64	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Helix	66	68	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	72	77	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	93	100	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	102	107	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	119	124	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	130	133	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Turn	135	137	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	139	145	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	147	149	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	151	156	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	162	167	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Turn	169	171	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	174	178	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU	
Q16878	UniProtKB	Beta strand	182	184	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6BPU