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Q16656

- NRF1_HUMAN

UniProt

Q16656 - NRF1_HUMAN

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Protein
Nuclear respiratory factor 1
Gene
NRF1
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi109 – 305197
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. cellular lipid metabolic process Source: Reactome
  2. generation of precursor metabolites and energy Source: ProtInc
  3. mitochondrion organization Source: Ensembl
  4. organ regeneration Source: Ensembl
  5. regulation of transcription from RNA polymerase II promoter Source: ProtInc
  6. response to electrical stimulus Source: Ensembl
  7. response to estradiol Source: Ensembl
  8. response to folic acid Source: Ensembl
  9. response to hypoxia Source: Ensembl
  10. response to lipopolysaccharide Source: Ensembl
  11. small molecule metabolic process Source: Reactome
  12. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

ReactomeiREACT_116145. PPARA activates gene expression.
REACT_200608. Transcriptional activation of mitochondrial biogenesis.

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear respiratory factor 1
Short name:
NRF-1
Alternative name(s):
Alpha palindromic-binding protein
Short name:
Alpha-pal
Gene namesi
Name:NRF1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:7996. NRF1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. extracellular vesicular exosome Source: UniProt
  3. nucleoplasm Source: Reactome
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31775.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 503503Nuclear respiratory factor 1
PRO_0000100208Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei39 – 391Phosphoserine; by CK2
Modified residuei44 – 441Phosphoserine; by CK2
Modified residuei46 – 461Phosphoserine; by CK2
Modified residuei47 – 471Phosphoserine; by CK2
Modified residuei52 – 521Phosphoserine; by CK2

Post-translational modificationi

Phosphorylation enhances DNA binding.

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ16656.
PaxDbiQ16656.
PRIDEiQ16656.

PTM databases

PhosphoSiteiQ16656.

Expressioni

Tissue specificityi

Ubiquitously expressed with strongest expression in skeletal muscle.

Gene expression databases

ArrayExpressiQ16656.
BgeeiQ16656.
CleanExiHS_NRF1.
GenevestigatoriQ16656.

Organism-specific databases

HPAiHPA029329.

Interactioni

Subunit structurei

Homodimer. Binds DNA as a dimer. Interacts with PPRC1.2 Publications

Protein-protein interaction databases

BioGridi110955. 2476 interactions.
IntActiQ16656. 3 interactions.
STRINGi9606.ENSP00000223190.

Structurei

3D structure databases

ProteinModelPortaliQ16656.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 7878Dimerization
Add
BLAST
Regioni301 – 476176Required for transcriptional activation
Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi88 – 11629Nuclear localization signal
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi41 – 6626Asp/Glu-rich (acidic)
Add
BLAST
Compositional biasi80 – 867Poly-Ala

Sequence similaritiesi

Belongs to the NRF1/Ewg family.

Phylogenomic databases

eggNOGiNOG80791.
HOGENOMiHOG000273898.
HOVERGENiHBG003062.
KOiK11831.
PhylomeDBiQ16656.
TreeFamiTF105308.

Family and domain databases

InterProiIPR019526. Nrf1_activation-bd.
IPR019525. Nrf1_NLS/DNA-bd_dimer.
[Graphical view]
PfamiPF10492. Nrf1_activ_bdg. 1 hit.
PF10491. Nrf1_DNA-bind. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. Align

Isoform Long (identifier: Q16656-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MEEHGVTQTE HMATIEAHAV AQQVQQVHVA TYTEHSMLSA DEDSPSSPED    50
TSYDDSDILN STAADEVTAH LAAAGPVGMA AAAAVATGKK RKRPHVFESN 100
PSIRKRQQTR LLRKLRATLD EYTTRVGQQA IVLCISPSKP NPVFKVFGAA 150
PLENVVRKYK SMILEDLESA LAEHAPAPQE VNSELPPLTI DGIPVSVDKM 200
TQAQLRAFIP EMLKYSTGRG KPGWGKESCK PIWWPEDIPW ANVRSDVRTE 250
EQKQRVSWTQ ALRTIVKNCY KQHGREDLLY AFEDQQTQTQ ATATHSIAHL 300
VPSQTVVQTF SNPDGTVSLI QVGTGATVAT LADASELPTT VTVAQVNYSA 350
VADGEVEQNW ATLQGGEMTI QTTQASEATQ AVASLAEAAV AASQEMQQGA 400
TVTMALNSEA AAHAVATLAE ATLQGGGQIV LSGETAAAVG ALTGVQDANG 450
LVQIPVSMYQ TVVTSLAQGN GPVQVAMAPV TTRISDSAVT MDGQAVEVVT 500
LEQ 503
Length:503
Mass (Da):53,541
Last modified:November 1, 1996 - v1
Checksum:iF31C358278371929
GO
Isoform Short (identifier: Q16656-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     256-321: Missing.

Show »
Length:437
Mass (Da):46,157
Checksum:iD7B62154D8D015B2
GO
Isoform 3 (identifier: Q16656-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-161: Missing.

Note: No experimental confirmation available.

Show »
Length:342
Mass (Da):36,051
Checksum:i5130FF5034DC7362
GO
Isoform 4 (identifier: Q16656-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     449-449: N → NGLFMADRAGRKWILTDKAT

Show »
Length:522
Mass (Da):55,674
Checksum:i580AC14584586AEF
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 161161Missing in isoform 3.
VSP_054330Add
BLAST
Alternative sequencei256 – 32166Missing in isoform Short.
VSP_003598Add
BLAST
Alternative sequencei449 – 4491N → NGLFMADRAGRKWILTDKAT in isoform 4.
VSP_054331

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti322 – 3221V → VV in AAA79013. 1 Publication
Sequence conflicti403 – 4031T → A in BAG56867. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L22454 mRNA. Translation: AAA16918.1.
U02683 mRNA. Translation: AAA21647.1.
U18383
, U18375, U18376, U18377, U18378, U18379, U18380, U18381, U18382 Genomic DNA. Translation: AAA79013.1.
EU159452 mRNA. Translation: ABV90872.1.
AK290891 mRNA. Translation: BAF83580.1.
AK293351 mRNA. Translation: BAG56867.1.
AC078846 Genomic DNA. No translation available.
AC084864 Genomic DNA. No translation available.
CH236950 Genomic DNA. Translation: EAL24100.1.
CH471070 Genomic DNA. Translation: EAW83728.1.
BC016925 mRNA. Translation: AAH16925.1.
CCDSiCCDS5813.2. [Q16656-1]
PIRiA54868.
RefSeqiNP_001035199.1. NM_001040110.1. [Q16656-1]
NP_005002.3. NM_005011.4. [Q16656-1]
UniGeneiHs.654363.

Genome annotation databases

EnsembliENST00000223190; ENSP00000223190; ENSG00000106459. [Q16656-1]
ENST00000311967; ENSP00000309826; ENSG00000106459.
ENST00000353868; ENSP00000342351; ENSG00000106459. [Q16656-2]
ENST00000393230; ENSP00000376922; ENSG00000106459. [Q16656-1]
ENST00000393232; ENSP00000376924; ENSG00000106459. [Q16656-1]
ENST00000539636; ENSP00000440455; ENSG00000106459.
GeneIDi4899.
KEGGihsa:4899.
UCSCiuc003voz.3. human. [Q16656-1]
uc003vpa.3. human.

Polymorphism databases

DMDMi12643732.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L22454 mRNA. Translation: AAA16918.1 .
U02683 mRNA. Translation: AAA21647.1 .
U18383
, U18375 , U18376 , U18377 , U18378 , U18379 , U18380 , U18381 , U18382 Genomic DNA. Translation: AAA79013.1 .
EU159452 mRNA. Translation: ABV90872.1 .
AK290891 mRNA. Translation: BAF83580.1 .
AK293351 mRNA. Translation: BAG56867.1 .
AC078846 Genomic DNA. No translation available.
AC084864 Genomic DNA. No translation available.
CH236950 Genomic DNA. Translation: EAL24100.1 .
CH471070 Genomic DNA. Translation: EAW83728.1 .
BC016925 mRNA. Translation: AAH16925.1 .
CCDSi CCDS5813.2. [Q16656-1 ]
PIRi A54868.
RefSeqi NP_001035199.1. NM_001040110.1. [Q16656-1 ]
NP_005002.3. NM_005011.4. [Q16656-1 ]
UniGenei Hs.654363.

3D structure databases

ProteinModelPortali Q16656.
ModBasei Search...

Protein-protein interaction databases

BioGridi 110955. 2476 interactions.
IntActi Q16656. 3 interactions.
STRINGi 9606.ENSP00000223190.

PTM databases

PhosphoSitei Q16656.

Polymorphism databases

DMDMi 12643732.

Proteomic databases

MaxQBi Q16656.
PaxDbi Q16656.
PRIDEi Q16656.

Protocols and materials databases

DNASUi 4899.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000223190 ; ENSP00000223190 ; ENSG00000106459 . [Q16656-1 ]
ENST00000311967 ; ENSP00000309826 ; ENSG00000106459 .
ENST00000353868 ; ENSP00000342351 ; ENSG00000106459 . [Q16656-2 ]
ENST00000393230 ; ENSP00000376922 ; ENSG00000106459 . [Q16656-1 ]
ENST00000393232 ; ENSP00000376924 ; ENSG00000106459 . [Q16656-1 ]
ENST00000539636 ; ENSP00000440455 ; ENSG00000106459 .
GeneIDi 4899.
KEGGi hsa:4899.
UCSCi uc003voz.3. human. [Q16656-1 ]
uc003vpa.3. human.

Organism-specific databases

CTDi 4899.
GeneCardsi GC07P129251.
HGNCi HGNC:7996. NRF1.
HPAi HPA029329.
MIMi 600879. gene.
neXtProti NX_Q16656.
PharmGKBi PA31775.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG80791.
HOGENOMi HOG000273898.
HOVERGENi HBG003062.
KOi K11831.
PhylomeDBi Q16656.
TreeFami TF105308.

Enzyme and pathway databases

Reactomei REACT_116145. PPARA activates gene expression.
REACT_200608. Transcriptional activation of mitochondrial biogenesis.

Miscellaneous databases

ChiTaRSi NRF1. human.
GeneWikii NRF1.
GenomeRNAii 4899.
NextBioi 18853.
PROi Q16656.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q16656.
Bgeei Q16656.
CleanExi HS_NRF1.
Genevestigatori Q16656.

Family and domain databases

InterProi IPR019526. Nrf1_activation-bd.
IPR019525. Nrf1_NLS/DNA-bd_dimer.
[Graphical view ]
Pfami PF10492. Nrf1_activ_bdg. 1 hit.
PF10491. Nrf1_DNA-bind. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "NRF-1, an activator involved in nuclear-mitochondrial interactions, utilizes a new DNA-binding domain conserved in a family of developmental regulators."
    Virbasius C.A., Virbasius J.V., Scarpulla R.C.
    Genes Dev. 7:2431-2445(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG), PROTEIN SEQUENCE OF 161-186 AND 256-263.
  2. "A key transcription factor for eukaryotic initiation factor-2 alpha is strongly homologous to developmental transcription factors and may link metabolic genes to cellular growth and development."
    Efiok B.J.S., Chiorini J.A., Safer B.
    J. Biol. Chem. 269:18921-18930(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG), PROTEIN SEQUENCE OF 161-183 AND 231-253.
  3. "Structure, expression, and chromosomal assignment of the human gene encoding nuclear respiratory factor 1."
    Gopalakrishnan L., Scarpulla R.C.
    J. Biol. Chem. 270:18019-18025(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Tissue: Placenta.
  4. Yang S.J., Li K.N., Zhang Y.Q.
    Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4).
    Tissue: Hepatoma.
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS LONG AND 3).
    Tissue: Urinary bladder.
  6. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "Human chromosome 7: DNA sequence and biology."
    Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K., Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R., Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A., Kanematsu E., Gentles S.
    , Christopoulos C.C., Choufani S., Kwasnicka D., Zheng X.H., Lai Z., Nusskern D.R., Zhang Q., Gu Z., Lu F., Zeesman S., Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R., Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N., Friedman J.M., Heng H.H.Q., Pelicci P.G., Lo-Coco F., Belloni E., Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A.P., Korf B.R., Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T., Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M., Gripp K.W., Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H., Teebi A., Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X., Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E., Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Doehner H., Doehner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J., Adams M.D., Tsui L.-C.
    Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  9. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
    Tissue: Duodenum.
  10. "The pre-mRNA of nuclear respiratory factor 1, a regulator of mitochondrial biogenesis, is alternatively spliced in human tissues and cell lines."
    Spelbrink J.N., Van den Bogert C.
    Hum. Mol. Genet. 4:1591-1596(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: ALTERNATIVE SPLICING.
  11. "Serine phosphorylation within a concise amino-terminal domain in nuclear respiratory factor 1 enhances DNA binding."
    Gugneja S., Scarpulla R.C.
    J. Biol. Chem. 272:18732-18739(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION OF DOMAINS, PHOSPHORYLATION.
  12. "Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells."
    Andersson U., Scarpulla R.C.
    Mol. Cell. Biol. 21:3738-3749(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH PPRC1.
  13. "PGC-1-related coactivator: immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth."
    Vercauteren K., Pasko R.A., Gleyzer N., Marino V.M., Scarpulla R.C.
    Mol. Cell. Biol. 26:7409-7419(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH PPRC1.
  14. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiNRF1_HUMAN
AccessioniPrimary (citable) accession number: Q16656
Secondary accession number(s): A8K4C6
, B4DDV6, Q15305, Q96AN2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: September 3, 2014
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi