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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRDEN375451:G1G6J-2926-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:RD1_3165
OrganismiRoseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans)
Taxonomic identifieri375451 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRoseobacter
Proteomesi
  • UP000007029 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000181081 – 580Arginine--tRNA ligaseAdd BLAST580

Proteomic databases

PRIDEiQ164C1

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi375451.RD1_3165

Structurei

3D structure databases

ProteinModelPortaliQ164C1
SMRiQ164C1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi131 – 141"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q164C1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLFAEMRAL VLECVDQMVT AGQLPADLNM TNVTVEPPRD AAHGDMATNA
60 70 80 90 100
AMVLAKPAGK KPRDIAEALA QLLAADARIA SAEVAGPGFL NLRIAPTAWR
110 120 130 140 150
AVLLSVLDKG TDFGRADIGA GQKVNVEYVS ANPTGPLHVG HTRGAVFGDA
160 170 180 190 200
LASLLDYAGF DVTREYYIND GGAQVDVLAR SVYLRYLEAH GQEVAFPDGT
210 220 230 240 250
YPGDYLIPVG QQLKDLKGDS YVGQPEEAWL QDIRTFATDA MMDLIRADLK
260 270 280 290 300
SLGVEMDVFY SEKSLYGTGR IEAAIEDLKS KGLIYDGVLE PPKGKKPEDW
310 320 330 340 350
EPREQTLFKS TEHGDDVDRP VMKSDGSWTY FAPDIAYHYD KVSRGYDALI
360 370 380 390 400
DVFGADHGGY VKRMKAAVSA LSDGKVPLDI KLTQLVKLFK NGEPFKMSKR
410 420 430 440 450
AGTFVTLRDV VDQVGPDVAR FVMLTRKNDA MLDFDFDKVM EQSRENPVFY
460 470 480 490 500
VQYAHARVAS VMRKAEAAGI AVDMDTLKAA DLSLLNHEAE LGLIAKLSEW
510 520 530 540 550
PRLVETAARS NEPHRVAFYL YELSGVFHGL WNRGNDVPEL RFVQDDPKVT
560 570 580
QAKIALARAC SVVIAAGLGI LGVTPAQEMR
Length:580
Mass (Da):63,493
Last modified:July 25, 2006 - v1
Checksum:iA42EEBD043390A06
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000362 Genomic DNA Translation: ABG32672.1
RefSeqiWP_011569288.1, NZ_FOOO01000004.1

Genome annotation databases

EnsemblBacteriaiABG32672; ABG32672; RD1_3165
KEGGirde:RD1_3165

Similar proteinsi

Entry informationi

Entry nameiSYR_ROSDO
AccessioniPrimary (citable) accession number: Q164C1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: May 23, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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