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Q162B6

- XYLA_ROSDO

UniProt

Q162B6 - XYLA_ROSDO

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Protein
Xylose isomerase
Gene
xylA, RD1_3705
Organism
Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei99 – 991 By similarity
Active sitei102 – 1021 By similarity
Metal bindingi230 – 2301Magnesium 1 By similarity
Metal bindingi266 – 2661Magnesium 1 By similarity
Metal bindingi266 – 2661Magnesium 2 By similarity
Metal bindingi269 – 2691Magnesium 2 By similarity
Metal bindingi294 – 2941Magnesium 1 By similarity
Metal bindingi305 – 3051Magnesium 2 By similarity
Metal bindingi307 – 3071Magnesium 2 By similarity
Metal bindingi337 – 3371Magnesium 1 By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Carbohydrate metabolism, Pentose shunt, Xylose metabolism

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciRDEN375451:GJIZ-3493-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomerase (EC:5.3.1.5)
Gene namesi
Name:xylA
Ordered Locus Names:RD1_3705
OrganismiRoseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans)
Taxonomic identifieri375451 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRoseobacter
ProteomesiUP000007029: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 433433Xylose isomeraseUniRule annotation
PRO_1000026454Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi375451.RD1_3705.

Structurei

3D structure databases

ProteinModelPortaliQ162B6.
SMRiQ162B6. Positions 2-433.

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.

Phylogenomic databases

eggNOGiCOG2115.
HOGENOMiHOG000252293.
KOiK01805.
OMAiKADSAFE.
OrthoDBiEOG62NX4R.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q162B6-1 [UniParc]FASTAAdd to Basket

« Hide

MTDFFKDIPA IRYEGPDTEN EFAFRHYNPD EVVMGKTLKD HLRFACAYWH    50
SFAWPGGDPF GGQTFERPWF GDTMELAKLK ADVAFDMFER LGVPYFCFHD 100
ADVRPEGDTF AESTKNLEEI TDYFAEKMDA TGVKLLWGTA NLFSHRRFMA 150
GAATNPDPEV FAYSAATIKS CMDATRKLGG ENYVLWGGRE GYETLLNTDM 200
ARERAQAGRM LQMVVDYKHK TGFAGTILIE PKPQEPTKHQ YDYDVATVYG 250
FLKDFGLEGE VKVNIEQGHA ILAGHSFEHE LALARALGIF GSIDMNRNDY 300
QSGWDTDQFP NNVPEMALAY YEVLRAGGFD TGGTNFDAKL RRQSLDPADL 350
ILAHVGGMDA CAAGLKAAAA MLEDGKLEAA REARYAGWSE GLGQKLLTSD 400
LAEISDLVIA KGINPQPRSG RQERLENLVN KYL 433
Length:433
Mass (Da):48,309
Last modified:July 25, 2006 - v1
Checksum:i6E9465CDEF79142E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000362 Genomic DNA. Translation: ABG33177.1.
RefSeqiWP_011569788.1. NC_008209.1.
YP_683863.1. NC_008209.1.

Genome annotation databases

EnsemblBacteriaiABG33177; ABG33177; RD1_3705.
GeneIDi4196123.
KEGGirde:RD1_3705.
PATRICi23365361. VBIRosDen86677_3546.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000362 Genomic DNA. Translation: ABG33177.1 .
RefSeqi WP_011569788.1. NC_008209.1.
YP_683863.1. NC_008209.1.

3D structure databases

ProteinModelPortali Q162B6.
SMRi Q162B6. Positions 2-433.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 375451.RD1_3705.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG33177 ; ABG33177 ; RD1_3705 .
GeneIDi 4196123.
KEGGi rde:RD1_3705.
PATRICi 23365361. VBIRosDen86677_3546.

Phylogenomic databases

eggNOGi COG2115.
HOGENOMi HOG000252293.
KOi K01805.
OMAi KADSAFE.
OrthoDBi EOG62NX4R.

Enzyme and pathway databases

BioCyci RDEN375451:GJIZ-3493-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33942 / OCh 114.

Entry informationi

Entry nameiXYLA_ROSDO
AccessioniPrimary (citable) accession number: Q162B6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: September 3, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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