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Protein

Xylose isomerase

Gene

xylA

Organism
Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei99UniRule annotation1
Active sitei102UniRule annotation1
Metal bindingi230Magnesium 1UniRule annotation1
Metal bindingi266Magnesium 1UniRule annotation1
Metal bindingi266Magnesium 2UniRule annotation1
Metal bindingi269Magnesium 2UniRule annotation1
Metal bindingi294Magnesium 1UniRule annotation1
Metal bindingi305Magnesium 2UniRule annotation1
Metal bindingi307Magnesium 2UniRule annotation1
Metal bindingi337Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism, Xylose metabolism
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciRDEN375451:G1G6J-3417-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:RD1_3705
OrganismiRoseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans)
Taxonomic identifieri375451 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRoseobacter
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000264541 – 433Xylose isomeraseAdd BLAST433

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi375451.RD1_3705

Structurei

3D structure databases

ProteinModelPortaliQ162B6
SMRiQ162B6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q162B6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDFFKDIPA IRYEGPDTEN EFAFRHYNPD EVVMGKTLKD HLRFACAYWH
60 70 80 90 100
SFAWPGGDPF GGQTFERPWF GDTMELAKLK ADVAFDMFER LGVPYFCFHD
110 120 130 140 150
ADVRPEGDTF AESTKNLEEI TDYFAEKMDA TGVKLLWGTA NLFSHRRFMA
160 170 180 190 200
GAATNPDPEV FAYSAATIKS CMDATRKLGG ENYVLWGGRE GYETLLNTDM
210 220 230 240 250
ARERAQAGRM LQMVVDYKHK TGFAGTILIE PKPQEPTKHQ YDYDVATVYG
260 270 280 290 300
FLKDFGLEGE VKVNIEQGHA ILAGHSFEHE LALARALGIF GSIDMNRNDY
310 320 330 340 350
QSGWDTDQFP NNVPEMALAY YEVLRAGGFD TGGTNFDAKL RRQSLDPADL
360 370 380 390 400
ILAHVGGMDA CAAGLKAAAA MLEDGKLEAA REARYAGWSE GLGQKLLTSD
410 420 430
LAEISDLVIA KGINPQPRSG RQERLENLVN KYL
Length:433
Mass (Da):48,309
Last modified:July 25, 2006 - v1
Checksum:i6E9465CDEF79142E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000362 Genomic DNA Translation: ABG33177.1
RefSeqiWP_011569788.1, NZ_FOOO01000012.1

Genome annotation databases

EnsemblBacteriaiABG33177; ABG33177; RD1_3705
KEGGirde:RD1_3705

Entry informationi

Entry nameiXYLA_ROSDO
AccessioniPrimary (citable) accession number: Q162B6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: April 25, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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