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Protein

Microtubule-associated protein

Gene

4R-MAP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Microtubule-associated proteinUniRule annotation
Gene namesi
Name:4R-MAP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Cytoplasmcytoskeleton UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. microtubule Source: UniProtKB-KW
  3. microtubule associated complex Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation, MicrotubuleUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiQ16296.

Expressioni

Gene expression databases

BgeeiQ16296.
ExpressionAtlasiQ16296. baseline and differential.

Family & Domainsi

Sequence similaritiesi

Contains 4 Tau/MAP repeats.UniRule annotation

Keywords - Domaini

RepeatUniRule annotation

Phylogenomic databases

HOVERGENiHBG103273.

Family and domain databases

InterProiIPR027324. MAP2/MAP4/Tau.
IPR001084. MAP_tubulin-bd_rpt.
[Graphical view]
PANTHERiPTHR11501. PTHR11501. 1 hit.
PfamiPF00418. Tubulin-binding. 4 hits.
[Graphical view]
PROSITEiPS00229. TAU_MAP_1. 3 hits.
PS51491. TAU_MAP_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q16296-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DLKNVKSKIG STDNIKYQPK GGQVRILNKK IDFSKVQSRC GSKDNIKHSA
60 70 80 90 100
GGGNVQIVTK KIDLSHVTSK CGSLKNIRHR PGGGRVKIES VKLDFKEKAQ
110 120
AKVGSLDNAH HVPGGGNVKI DSQKL
Length:125
Mass (Da):13,495
Last modified:November 1, 1996 - v1
Checksum:i4357622E1A6C34B9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei125 – 1251Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S76756 mRNA. Translation: AAB33379.1.
PIRiI52650.
UniGeneiHs.368281.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S76756 mRNA. Translation: AAB33379.1.
PIRiI52650.
UniGeneiHs.368281.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ16296.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG103273.

Gene expression databases

BgeeiQ16296.
ExpressionAtlasiQ16296. baseline and differential.

Family and domain databases

InterProiIPR027324. MAP2/MAP4/Tau.
IPR001084. MAP_tubulin-bd_rpt.
[Graphical view]
PANTHERiPTHR11501. PTHR11501. 1 hit.
PfamiPF00418. Tubulin-binding. 4 hits.
[Graphical view]
PROSITEiPS00229. TAU_MAP_1. 3 hits.
PS51491. TAU_MAP_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Four repeat MAP2 isoforms in human and rat brain."
    Kindler S., Garner C.C.
    Brain Res. Mol. Brain Res. 26:218-224(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ16296_HUMAN
AccessioniPrimary (citable) accession number: Q16296
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.