Q161S5 (UREF_ROSDO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease accessory protein UreF

Gene names

Name:	ureF
Ordered Locus Names:	RD1_3804

Organism

Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans) [Complete proteome] [HAMAP]

Taxonomic identifier

375451 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Roseobacter

Protein attributes

Sequence length	222 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter By similarity. HAMAP MF_01385
Subunit structure	UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_01385.
Sequence similarities	Belongs to the UreF family.

Ontologies

Keywords
Biological process	Nickel insertion
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 222	222	Urease accessory protein UreF HAMAP MF_01385		PRO_0000344173

Sequences

	Sequence		Length	Mass (Da)
	Q161S5 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: 21CA587BE5782A0A	FASTA	222	23,718
	10 20 30 40 50 60 MTIHTSRIIM STDAFLTLTQ WLSPGFPVGA YAYSHGLEQV IDCGDMRDAK ALQDWVEDIL 70 80 90 100 110 120 EHGSGTSDGI LLAASYKALP EDVSRIDAIA RAFASSAERV TETVDQGAAF AKAVDAIWAT 130 140 150 160 170 180 DLGQLCYPVA VGRAACAQGL PLDLTLEIYT HAFAANLVSA AVRLVPLGQT EGQAVLAALA 190 200 210 220 PLIRQVARRC HDAGIDDLTT ACMALDIAAM HHETQYSKVF RT

References

[1]

"The complete genome sequence of Roseobacter denitrificans reveals a mixotrophic rather than photosynthetic metabolism." Swingley W.D., Sadekar S., Mastrian S.D., Matthies H.J., Hao J., Ramos H., Acharya C.R., Conrad A.L., Taylor H.L., Dejesa L.C., Shah M.K., O'Huallachain M.E., Lince M.T., Blankenship R.E., Beatty J.T., Touchman J.W. J. Bacteriol. 189:683-690(2007) [PubMed: 17098896] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33942 / OCh 114.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000362 Genomic DNA. Translation: ABG33268.1.
RefSeq	YP_683954.1. NC_008209.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q161S5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4198849.
GenomeReviews	Gene locus RD1_3804 in contig CP000362_GR.
KEGG	rde:RD1_3804.
NMPDR	fig|375451.6.peg.3534.
PATRIC	23365541. VBIRosDen86677_3636.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0830.
HOGENOM	HBG709295.
OMA	WLSPAFP.
ProtClustDB	CLSK759156.
Enzyme and pathway databases
BioCyc	RDEN375451:RD1_3804-MONOMER.
Family and domain databases
HAMAP	MF_01385. UreF. [Tree]
InterPro	IPR002639. UreF. [Graphical view]
KO	K03188.
Pfam	PF01730. UreF. 1 hit. [Graphical view]
PIRSF	PIRSF009467. Ureas_acces_UreF. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UREF_ROSDO

Accession

Primary (citable) accession number: Q161S5

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 22, 2008
Last sequence update:	July 25, 2006
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program