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Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciPATL342610:GHGT-22-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:Patl_0022
OrganismiPseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Taxonomic identifieri342610 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
Proteomesi
  • UP000001981 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 315315Methionyl-tRNA formyltransferasePRO_1000058405Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi342610.Patl_0022.

Structurei

3D structure databases

ProteinModelPortaliQ15ZY3.
SMRiQ15ZY3. Positions 5-314.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni113 – 1164Tetrahydrofolate (THF) bindingUniRule annotation

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CAE. Bacteria.
COG0223. LUCA.
HOGENOMiHOG000261177.
KOiK00604.
OMAiQRDKPFG.
OrthoDBiPOG091H01YM.

Family and domain databases

Gene3Di3.10.25.10. 1 hit.
3.40.50.170. 1 hit.
HAMAPiMF_00182. Formyl_trans. 1 hit.
InterProiIPR005794. Fmt.
IPR005793. Formyl_trans_C.
IPR002376. Formyl_transf_N.
IPR011034. Formyl_transferase_C-like.
IPR001555. GART_AS.
[Graphical view]
PfamiPF02911. Formyl_trans_C. 1 hit.
PF00551. Formyl_trans_N. 1 hit.
[Graphical view]
SUPFAMiSSF50486. SSF50486. 1 hit.
SSF53328. SSF53328. 1 hit.
TIGRFAMsiTIGR00460. fmt. 1 hit.
PROSITEiPS00373. GART. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q15ZY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSGLKIVFA GTPEFAANHL SALIESEHQV IAAYTQPDRP AGRGKKLHAS
60 70 80 90 100
AVKQLAQQHD IPVYQPASLK SEEAQQQLAA LNADVMVVVA YGLILPQIIL
110 120 130 140 150
DTPKYGCLNV HGSLLPKWRG AAPIQRAIWA GDAETGVTIM QMDKGLDTGA
160 170 180 190 200
VLSELRLAIT PIDTSATLYT KLAELGPKGL LETLASLGDL TPQAQDNTLA
210 220 230 240 250
TYAEKLSKQE AKIDWTMTAA QLERNVRAFD PWPVAYFEAN GAAIKVRSAE
260 270 280 290 300
VQQTPICDNA KPGQIIQADK HAIGVQTGDG VLLIKTLQLP GKKPLATQDI
310
LNGHSDWFSV GTILS
Length:315
Mass (Da):33,796
Last modified:July 25, 2006 - v1
Checksum:i4321CBD245D5086B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000388 Genomic DNA. Translation: ABG38555.1.
RefSeqiWP_011572970.1. NC_008228.1.

Genome annotation databases

EnsemblBacteriaiABG38555; ABG38555; Patl_0022.
KEGGipat:Patl_0022.
PATRICi23044810. VBIPseAtl25434_0022.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000388 Genomic DNA. Translation: ABG38555.1.
RefSeqiWP_011572970.1. NC_008228.1.

3D structure databases

ProteinModelPortaliQ15ZY3.
SMRiQ15ZY3. Positions 5-314.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi342610.Patl_0022.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG38555; ABG38555; Patl_0022.
KEGGipat:Patl_0022.
PATRICi23044810. VBIPseAtl25434_0022.

Phylogenomic databases

eggNOGiENOG4105CAE. Bacteria.
COG0223. LUCA.
HOGENOMiHOG000261177.
KOiK00604.
OMAiQRDKPFG.
OrthoDBiPOG091H01YM.

Enzyme and pathway databases

BioCyciPATL342610:GHGT-22-MONOMER.

Family and domain databases

Gene3Di3.10.25.10. 1 hit.
3.40.50.170. 1 hit.
HAMAPiMF_00182. Formyl_trans. 1 hit.
InterProiIPR005794. Fmt.
IPR005793. Formyl_trans_C.
IPR002376. Formyl_transf_N.
IPR011034. Formyl_transferase_C-like.
IPR001555. GART_AS.
[Graphical view]
PfamiPF02911. Formyl_trans_C. 1 hit.
PF00551. Formyl_trans_N. 1 hit.
[Graphical view]
SUPFAMiSSF50486. SSF50486. 1 hit.
SSF53328. SSF53328. 1 hit.
TIGRFAMsiTIGR00460. fmt. 1 hit.
PROSITEiPS00373. GART. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFMT_PSEA6
AccessioniPrimary (citable) accession number: Q15ZY3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 25, 2006
Last modified: September 7, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.