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Q15Z55

- GCH4_PSEA6

UniProt

Q15Z55 - GCH4_PSEA6

Protein

GTP cyclohydrolase FolE2

Gene

folE2

Organism
Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (25 Jul 2006)
      Previous versions | rss
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    • Comment

    Functioni

    Converts GTP to 7,8-dihydroneopterin triphosphate.UniRule annotation

    Catalytic activityi

    GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei155 – 1551May be catalytically importantUniRule annotation

    GO - Molecular functioni

    1. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciPATL342610:GHGT-307-MONOMER.
    UniPathwayiUPA00848; UER00151.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTP cyclohydrolase FolE2UniRule annotation (EC:3.5.4.16UniRule annotation)
    Gene namesi
    Name:folE2UniRule annotation
    Ordered Locus Names:Patl_0301
    OrganismiPseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
    Taxonomic identifieri342610 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
    ProteomesiUP000001981: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 306306GTP cyclohydrolase FolE2PRO_0000289505Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi342610.Patl_0301.

    Structurei

    3D structure databases

    ProteinModelPortaliQ15Z55.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP cyclohydrolase IV family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1469.
    HOGENOMiHOG000247517.
    KOiK09007.
    OMAiAGRTTIQ.
    OrthoDBiEOG6X6RBH.

    Family and domain databases

    HAMAPiMF_01527_B. GTP_cyclohydrol_B.
    InterProiIPR022838. GTP_cyclohydrolase_FolE2.
    IPR003801. GTP_cyclohydrolase_FolE2/MptA.
    [Graphical view]
    PfamiPF02649. GCHY-1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q15Z55-1 [UniParc]FASTAAdd to Basket

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    MGMTLPDITS SENVASAAPL KWVGMEGITV PIQVPMSGEV PAYVNAKTDV    50
    YVSLDKSDAK GIHMSRLFLK LNDILGTELL SSTSLTALLN ELILSQQGLS 100
    QGAKVNLDFA LTLRKKALLS NEFGYQSYPI GISTQLVKGV ARTVLSLTIA 150
    YSSTCPCSSA LAQQALSDAI SQRFDDEMIS KSELTQWITS KTGAVATPHS 200
    QRSYAYIKLT LDGDALPNLP ELITLLETTI GTPVQTAVKR QDEQAFAKLN 250
    AENLMFCEDA ARRLKRALER KENVLDYWFK VEHQESLHAH NAVAIDFKDN 300
    ADEDTM 306
    Length:306
    Mass (Da):33,502
    Last modified:July 25, 2006 - v1
    Checksum:i853227950BC4DA35
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000388 Genomic DNA. Translation: ABG38833.1.
    RefSeqiWP_011573231.1. NC_008228.1.
    YP_659887.1. NC_008228.1.

    Genome annotation databases

    EnsemblBacteriaiABG38833; ABG38833; Patl_0301.
    GeneIDi4172895.
    KEGGipat:Patl_0301.
    PATRICi23045410. VBIPseAtl25434_0316.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000388 Genomic DNA. Translation: ABG38833.1 .
    RefSeqi WP_011573231.1. NC_008228.1.
    YP_659887.1. NC_008228.1.

    3D structure databases

    ProteinModelPortali Q15Z55.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 342610.Patl_0301.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABG38833 ; ABG38833 ; Patl_0301 .
    GeneIDi 4172895.
    KEGGi pat:Patl_0301.
    PATRICi 23045410. VBIPseAtl25434_0316.

    Phylogenomic databases

    eggNOGi COG1469.
    HOGENOMi HOG000247517.
    KOi K09007.
    OMAi AGRTTIQ.
    OrthoDBi EOG6X6RBH.

    Enzyme and pathway databases

    UniPathwayi UPA00848 ; UER00151 .
    BioCyci PATL342610:GHGT-307-MONOMER.

    Family and domain databases

    HAMAPi MF_01527_B. GTP_cyclohydrol_B.
    InterProi IPR022838. GTP_cyclohydrolase_FolE2.
    IPR003801. GTP_cyclohydrolase_FolE2/MptA.
    [Graphical view ]
    Pfami PF02649. GCHY-1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: T6c / ATCC BAA-1087.

    Entry informationi

    Entry nameiGCH4_PSEA6
    AccessioniPrimary (citable) accession number: Q15Z55
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 29, 2007
    Last sequence update: July 25, 2006
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3