SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q15VK0

- SYL_PSEA6

UniProt

Q15VK0 - SYL_PSEA6

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Leucine--tRNA ligase
Gene
leuS, Patl_1566
Organism
Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei629 – 6291ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. aminoacyl-tRNA editing activity Source: InterPro
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPATL342610:GHGT-1595-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligase (EC:6.1.1.4)
Alternative name(s):
Leucyl-tRNA synthetase
Short name:
LeuRS
Gene namesi
Name:leuS
Ordered Locus Names:Patl_1566
OrganismiPseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Taxonomic identifieri342610 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
ProteomesiUP000001981: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 870870Leucine--tRNA ligaseUniRule annotation
PRO_0000334793Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi342610.Patl_1566.

Structurei

3D structure databases

ProteinModelPortaliQ15VK0.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi43 – 5311"HIGH" regionUniRule annotation
Add
BLAST
Motifi626 – 6305"KMSKS" regionUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200747.
KOiK01869.
OMAiHISHELW.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q15VK0-1 [UniParc]FASTAAdd to Basket

« Hide

MAEKIYEPQK IEQEVQALWE TNQTFKATEQ EDKEKFYCLS MFPYPSGRLH    50
MGHVRNYTIG DVVSRFQRMN GKNVLQPMGW DAFGLPAENA ALNNNTAPAK 100
WTYQNIDYMK NQLKSLGFGY DWDREVATCK KDYYRWEQWF FTRLYEKGLV 150
YKKNSTVNWD PVDHTVLANE QVIDGRGWRS GALVEQKEIP QWFIKITDYA 200
EELLTDLEQL EDWPEQVRAM QKNWIGRSEG VDITFNLSEN AADISSFDVY 250
TTRPDTLYGV TYVAVAAQHP LALHAAQTRP ELAEFIESCK NTKVAEAELA 300
TMEKKGCDTG LFAIHPLTGE KVAVWVANFV LMGYGSGAVM SVPGHDQRDW 350
EFAQKYGLPI KQVVEPSADE PQECDLTTAA YTDKGVLVNS AEFNGLAFQE 400
AFDAIAAKLE ALGAGSKKVN YRLRDWGVSR QRYWGSPIPM LNLENGESVP 450
VPSDQLPVEL PEDVQMNGVI SPIKADPDWA KTEYNGQPAL RETDTFDTFM 500
ESSWYYARYC SAQNQDAMLD PTQANYWLPV DQYVGGIEHA ILHLLYSRFF 550
HKLLRDEGLV NSDEPYKRLL CQGMVLADSF FREDESGKKE WFSPADVDTV 600
KDEKGRITQA TLKADGKPVE HGGMTKMSKS KNNGIDPQHV IDLYGADTIR 650
VFTMFAAPPE QTLEWVDSGV EGANRFIKRV WKLTQDHIDA LDGDTAPAID 700
KTALTGDQKT LRRAVHRTIA KVTDDVGRRQ TFNTAVAAIM ELLNSLQRAP 750
QSTDQDKAVL REAIESVVLL LNPIAPHMCH ILWHDLGHKN DIETAPWPAV 800
DESALVEDEK LIIVQVNGKV RSKITVAADA SQEEVQALGL AQENVQQFVD 850
GKTIRKVIYI AGKLLNIVAN 870
Length:870
Mass (Da):98,121
Last modified:July 25, 2006 - v1
Checksum:i6FB0DCCA8696AD1F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000388 Genomic DNA. Translation: ABG40088.1.
RefSeqiYP_661142.1. NC_008228.1.

Genome annotation databases

EnsemblBacteriaiABG40088; ABG40088; Patl_1566.
GeneIDi4172558.
KEGGipat:Patl_1566.
PATRICi23048160. VBIPseAtl25434_1671.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000388 Genomic DNA. Translation: ABG40088.1 .
RefSeqi YP_661142.1. NC_008228.1.

3D structure databases

ProteinModelPortali Q15VK0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 342610.Patl_1566.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG40088 ; ABG40088 ; Patl_1566 .
GeneIDi 4172558.
KEGGi pat:Patl_1566.
PATRICi 23048160. VBIPseAtl25434_1671.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200747.
KOi K01869.
OMAi HISHELW.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci PATL342610:GHGT-1595-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: T6c / ATCC BAA-1087.

Entry informationi

Entry nameiSYL_PSEA6
AccessioniPrimary (citable) accession number: Q15VK0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 25, 2006
Last modified: May 14, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi