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Protein

Ribosomal RNA large subunit methyltransferase F

Gene

rlmF

Organism
Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the adenine in position 1618 of 23S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPATL342610:GHGT-1613-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase FUniRule annotation (EC:2.1.1.181UniRule annotation)
Alternative name(s):
23S rRNA mA1618 methyltransferaseUniRule annotation
rRNA adenine N-6-methyltransferaseUniRule annotation
Gene namesi
Name:rlmFUniRule annotation
Ordered Locus Names:Patl_1583
OrganismiPseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Taxonomic identifieri342610 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
Proteomesi
  • UP000001981 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 330330Ribosomal RNA large subunit methyltransferase FPRO_0000349923Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi342610.Patl_1583.

Structurei

3D structure databases

ProteinModelPortaliQ15VI3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. METTL16/RlmF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiEOG6742SX.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 1 hit.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

Q15VI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTITTTVKAK TLAVNNKNAP HTSATMHPRN VHRNGYPMSA LCQSYPTLEA
60 70 80 90 100
HVIKAKSGQQ SIDFSKAASV KALNAALLIH YYGLNMWDIP EGYLCPPVPG
110 120 130 140 150
RADYIHGLAD LLAKDNKGVV PTGNRVIGLD IGVGANAIYP IIGSQTYGWD
160 170 180 190 200
FVGSDIDDVA LKSATTLANN NPKLKPLLAV RKQHDKAYIF AGIIQPDDHF
210 220 230 240 250
TFSLCNPPFH KSAEEAAMGS LRKVKGLGRN KQKSNNTGNA QPITANKLNF
260 270 280 290 300
AGQSNELWCD GGELAFIQRM IKESVEYQSQ VGWFTCLVSK SLHLKAIETS
310 320 330
ARYFGAKQFM KVDMGQGQKI SRFVAWKFRD
Length:330
Mass (Da):36,184
Last modified:July 25, 2006 - v1
Checksum:i927483D31C469D06
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000388 Genomic DNA. Translation: ABG40105.1.

Genome annotation databases

EnsemblBacteriaiABG40105; ABG40105; Patl_1583.
KEGGipat:Patl_1583.
PATRICi23048196. VBIPseAtl25434_1688.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000388 Genomic DNA. Translation: ABG40105.1.

3D structure databases

ProteinModelPortaliQ15VI3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi342610.Patl_1583.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG40105; ABG40105; Patl_1583.
KEGGipat:Patl_1583.
PATRICi23048196. VBIPseAtl25434_1688.

Phylogenomic databases

eggNOGiENOG4105EBA. Bacteria.
COG3129. LUCA.
HOGENOMiHOG000218605.
KOiK06970.
OMAiVTLCNPP.
OrthoDBiEOG6742SX.

Enzyme and pathway databases

BioCyciPATL342610:GHGT-1613-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01848. 23SrRNA_methyltr_F.
InterProiIPR016909. rRNA_lsu_MeTfrase_F.
IPR010286. rRNA_lsu_MeTfrase_F-like.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PANTHERiPTHR13393. PTHR13393. 1 hit.
PfamiPF05971. Methyltransf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF029038. Mtase_YbiN_prd. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: T6c / ATCC BAA-1087.

Entry informationi

Entry nameiRLMF_PSEA6
AccessioniPrimary (citable) accession number: Q15VI3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: July 25, 2006
Last modified: November 11, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.