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Q15VD4

- PNP_PSEA6

UniProt

Q15VD4 - PNP_PSEA6

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Protein

Polyribonucleotide nucleotidyltransferase

Gene

pnp

Organism
Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Magnesium.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi485 – 4851MagnesiumUniRule annotation
Metal bindingi491 – 4911MagnesiumUniRule annotation

GO - Molecular functioni

  1. 3'-5'-exoribonuclease activity Source: InterPro
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP
  4. RNA binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. mRNA catabolic process Source: UniProtKB-HAMAP
  2. RNA processing Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

Magnesium, Metal-binding, RNA-binding

Enzyme and pathway databases

BioCyciPATL342610:GHGT-1662-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferaseUniRule annotation (EC:2.7.7.8UniRule annotation)
Alternative name(s):
Polynucleotide phosphorylaseUniRule annotation
Short name:
PNPaseUniRule annotation
Gene namesi
Name:pnpUniRule annotation
Ordered Locus Names:Patl_1632
OrganismiPseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Taxonomic identifieri342610 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
ProteomesiUP000001981: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 703703Polyribonucleotide nucleotidyltransferasePRO_0000329776Add
BLAST

Interactioni

Subunit structurei

Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.UniRule annotation

Protein-protein interaction databases

STRINGi342610.Patl_1632.

Structurei

3D structure databases

ProteinModelPortaliQ15VD4.
SMRiQ15VD4. Positions 616-690.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini552 – 61160KHUniRule annotationAdd
BLAST
Domaini621 – 68969S1 motifUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the polyribonucleotide nucleotidyltransferase family.UniRule annotation
Contains 1 KH domain.UniRule annotation
Contains 1 S1 motif domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG1185.
HOGENOMiHOG000218326.
KOiK00962.
OMAiPRWDWVA.
OrthoDBiEOG6WT8CC.

Family and domain databases

Gene3Di1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPiMF_01595. PNPase.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. S1_dom.
[Graphical view]
PANTHERiPTHR11252. PTHR11252. 1 hit.
PfamiPF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view]
PIRSFiPIRSF005499. PNPase. 1 hit.
SMARTiSM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q15VD4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTPITKSFQY GQHTVTLETG VIARQATAAV MASMDDTSVL VSVVGKKDTK
60 70 80 90 100
PGQDFFPLTV NYQERTYAAG KIPGGFFKRE GRPSEYETLT SRLIDRPIRP
110 120 130 140 150
LFPDGFMNEV QIIVTVVSAN PEIPTDIISL IGTSAALAIS GMPFNGPVGA
160 170 180 190 200
ARVGYTDGQY VLNTRTSELE ISQLDLVVAG TKGAVLMVES EAEVLSEDVM
210 220 230 240 250
LGAVMFGHEQ MQTVVNAVTE FAAEVNTPKW DWVAEPANVT LKDKIKALAE
260 270 280 290 300
AEMTEAYQIS DKMARKDAIV ALTDKTVAAI VEADAEQDAK EVSELLHELE
310 320 330 340 350
SDVVRSRILA GQPRIDGRDP AMIRALDVAT GILPRTHGSA LFTRGETQAI
360 370 380 390 400
VAATLGTERD AQMIDGLNGK VDSRFMLHYN FPPYCVGETG FVGSPKRREI
410 420 430 440 450
GHGRLAKRGI QAVMPSEKEF PYVVRVVSEI TESNGSSSMA SVCGTSLALM
460 470 480 490 500
DAGVPIKASV AGIAMGLVKN DENFVVLSDI LGDEDHLGDM DFKVAGTTEG
510 520 530 540 550
ITALQMDIKI EGITQEIMQV ALKQAKEARL HILGVMDQAI SGHRDEMSEF
560 570 580 590 600
APRIYTLKID QDKIRDVIGK GGAMIRSITE ASDTNIEIED DGTIKIFATE
610 620 630 640 650
RAKADIAISK IEQVTADVEA GKTYEGKVTR IVDFGAFVEI LPGKEGLVHI
660 670 680 690 700
SQIAHERVNK VADHLSEGQI INVKVMEIDR QNRVRLSIKE LLEKPAAPAE

GNE
Length:703
Mass (Da):76,143
Last modified:July 25, 2006 - v1
Checksum:i83B2C6DB6201F480
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000388 Genomic DNA. Translation: ABG40154.1.
RefSeqiWP_011574461.1. NC_008228.1.
YP_661208.1. NC_008228.1.

Genome annotation databases

EnsemblBacteriaiABG40154; ABG40154; Patl_1632.
GeneIDi4174061.
KEGGipat:Patl_1632.
PATRICi23048294. VBIPseAtl25434_1737.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000388 Genomic DNA. Translation: ABG40154.1 .
RefSeqi WP_011574461.1. NC_008228.1.
YP_661208.1. NC_008228.1.

3D structure databases

ProteinModelPortali Q15VD4.
SMRi Q15VD4. Positions 616-690.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 342610.Patl_1632.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG40154 ; ABG40154 ; Patl_1632 .
GeneIDi 4174061.
KEGGi pat:Patl_1632.
PATRICi 23048294. VBIPseAtl25434_1737.

Phylogenomic databases

eggNOGi COG1185.
HOGENOMi HOG000218326.
KOi K00962.
OMAi PRWDWVA.
OrthoDBi EOG6WT8CC.

Enzyme and pathway databases

BioCyci PATL342610:GHGT-1662-MONOMER.

Family and domain databases

Gene3Di 1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPi MF_01595. PNPase.
InterProi IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. S1_dom.
[Graphical view ]
PANTHERi PTHR11252. PTHR11252. 1 hit.
Pfami PF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 2 hits.
PF00575. S1. 1 hit.
[Graphical view ]
PIRSFi PIRSF005499. PNPase. 1 hit.
SMARTi SM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
PROSITEi PS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: T6c / ATCC BAA-1087.

Entry informationi

Entry nameiPNP_PSEA6
AccessioniPrimary (citable) accession number: Q15VD4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: July 25, 2006
Last modified: October 29, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3