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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei67L-glutamineUniRule annotation1
Binding sitei212L-glutamineUniRule annotation1
Binding sitei231ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi35 – 37ATPUniRule annotation3
Nucleotide bindingi41 – 47ATPUniRule annotation7
Nucleotide bindingi261 – 262ATPUniRule annotation2
Nucleotide bindingi269 – 271ATPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:Patl_2184
OrganismiPseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Taxonomic identifieri342610 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
Proteomesi
  • UP000001981 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000954991 – 558Glutamine--tRNA ligaseAdd BLAST558

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi342610.Patl_2184.

Structurei

3D structure databases

ProteinModelPortaliQ15TT6.
SMRiQ15TT6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi34 – 44"HIGH" regionUniRule annotationAdd BLAST11
Motifi268 – 272"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiPOG091H00G9.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_N.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q15TT6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAETESRPTN FIRQIIDKDL QSGLHKQIHT RFPPEPNGYL HIGHAKSICL
60 70 80 90 100
NFGIAQDYQG QCNLRFDDTN PDKEDIDYVN AIKNDVIWLG FEWHGEARYS
110 120 130 140 150
SNYFDQLHAY AVELIEKGLA YVDFSNQEQV REMRGTLTTP GTNSPYRDTS
160 170 180 190 200
IEENIAQFAK MRNGEYKEGE CLLRAKIDMS SPFMCMRDPA LYRVKFAHHH
210 220 230 240 250
QTGDKWCIYP MYDFTHCISD AIEGITHSLC TLEFQDNRRL YDWVLENVTI
260 270 280 290 300
DVVPRQYEFS RLNLEYTVLS KRKLIQLVDE EFVSGWDDPR MPTIAGLRRR
310 320 330 340 350
GFTAASIREF CKRIGVTKMD NMVEMSMLEA PLRDELNENA PRAMAVLEPV
360 370 380 390 400
KIVIENYPQD GVELLAAPNH PNRPELGSRE VPFAREIYIE AEDFREEANK
410 420 430 440 450
KFKRLVLGKE VRLRNAYVIK AQRVEKDEQG NVTTIFCEYD GDTLGKDPAD
460 470 480 490 500
GRKVKGVIHW VSAAHAVAAE IRLYDSLFTV PNPAAEDDFV ACINPESLTV
510 520 530 540 550
KQGWVEPSLA KVDIDEANIQ AFQFERTGYF CFDKDSTTSK LVFNRTVGLR

DTWAKIGD
Length:558
Mass (Da):64,120
Last modified:July 25, 2006 - v1
Checksum:i5F391A3312D13F46
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000388 Genomic DNA. Translation: ABG40702.1.
RefSeqiWP_011574986.1. NC_008228.1.

Genome annotation databases

EnsemblBacteriaiABG40702; ABG40702; Patl_2184.
KEGGipat:Patl_2184.

Similar proteinsi

Entry informationi

Entry nameiSYQ_PSEA6
AccessioniPrimary (citable) accession number: Q15TT6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 25, 2006
Last modified: November 22, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families