Q15TT6 (SYQ_PSEA6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamine--tRNA ligase
EC=6.1.1.18

Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS

Gene names

Name:	glnS
Ordered Locus Names:	Patl_2184

Organism

Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) [Complete proteome] [HAMAP]

Taxonomic identifier

342610 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas

Protein attributes

Sequence length	558 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP MF_00126
Subunit structure	Monomer By similarity. HAMAP MF_00126
Subcellular location	Cytoplasm By similarity HAMAP MF_00126.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glutaminyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glutamine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 558	558	Glutamine--tRNA ligase HAMAP MF_00126		PRO_1000095499
Regions
	Motif	34 – 44	11	"HIGH" region HAMAP MF_00126
	Motif	268 – 272	5	"KMSKS" region HAMAP MF_00126
Sites
	Binding site	271	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q15TT6 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: 5F391A3312D13F46	FASTA	558	64,120
	10 20 30 40 50 60 MAETESRPTN FIRQIIDKDL QSGLHKQIHT RFPPEPNGYL HIGHAKSICL NFGIAQDYQG 70 80 90 100 110 120 QCNLRFDDTN PDKEDIDYVN AIKNDVIWLG FEWHGEARYS SNYFDQLHAY AVELIEKGLA 130 140 150 160 170 180 YVDFSNQEQV REMRGTLTTP GTNSPYRDTS IEENIAQFAK MRNGEYKEGE CLLRAKIDMS 190 200 210 220 230 240 SPFMCMRDPA LYRVKFAHHH QTGDKWCIYP MYDFTHCISD AIEGITHSLC TLEFQDNRRL 250 260 270 280 290 300 YDWVLENVTI DVVPRQYEFS RLNLEYTVLS KRKLIQLVDE EFVSGWDDPR MPTIAGLRRR 310 320 330 340 350 360 GFTAASIREF CKRIGVTKMD NMVEMSMLEA PLRDELNENA PRAMAVLEPV KIVIENYPQD 370 380 390 400 410 420 GVELLAAPNH PNRPELGSRE VPFAREIYIE AEDFREEANK KFKRLVLGKE VRLRNAYVIK 430 440 450 460 470 480 AQRVEKDEQG NVTTIFCEYD GDTLGKDPAD GRKVKGVIHW VSAAHAVAAE IRLYDSLFTV 490 500 510 520 530 540 PNPAAEDDFV ACINPESLTV KQGWVEPSLA KVDIDEANIQ AFQFERTGYF CFDKDSTTSK 550 LVFNRTVGLR DTWAKIGD

References

[1]

"Complete sequence of Pseudoalteromonas atlantica T6c." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Karls A.C., Bartlett D., Higgins B.P., Richardson P. Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: T6c / ATCC BAA-1087.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000388 Genomic DNA. Translation: ABG40702.1.
RefSeq	YP_661756.1. NC_008228.1.
3D structure databases
ProteinModelPortal	Q15TT6.
SMR	Q15TT6. Positions 9-552.
ModBase	Search...
Protein-protein interaction databases
STRING	Q15TT6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4172336.
GenomeReviews	Gene locus Patl_2184 in contig CP000388_GR.
KEGG	pat:Patl_2184.
NMPDR	fig|342610.3.peg.3156.
PATRIC	23049492. VBIPseAtl25434_2334.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0008.
HOGENOM	HBG334108.
OMA	RMPTIAG.
PhylomeDB	Q15TT6.
ProtClustDB	PRK05347.
Enzyme and pathway databases
BioCyc	PATL342610:PATL_2184-MONOMER.
Family and domain databases
HAMAP	MF_00126. Gln_tRNA_synth. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR004514. Gln-tRNA-synth_Ib. IPR022861. Gln_tRNA_synth_bac. IPR000924. Glu/Gln-tRNA-synth_Ib. IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl. IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom. IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd. IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl. IPR011035. Ribosomal_L25/Gln-tRNA_synth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:1.10.1160.10. Glu/Gln-tRNA-synth_Ic_a-bdl. 1 hit. G3DSA:2.40.240.10. Rbsml_L25/Gln-tRNA_synth_b-brl. 2 hits. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K01886.
PANTHER	PTHR10119. Glu_tRNA-synt_1c. 1 hit.
Pfam	PF00749. tRNA-synt_1c. 1 hit. PF03950. tRNA-synt_1c_C. 1 hit. [Graphical view]
PRINTS	PR00987. TRNASYNTHGLU.
SUPFAM	SSF50715. Ribosomal_L25rel. 1 hit.
TIGRFAMs	TIGR00440. GlnS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYQ_PSEA6

Accession

Primary (citable) accession number: Q15TT6

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	July 25, 2006
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program