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Q15SR8 (Q15SR8_PSEA6) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
ATP-dependent dethiobiotin synthetase BioD HAMAP-Rule MF_00336
EC=6.3.3.3 HAMAP-Rule MF_00336
Alternative name(s):
DTB synthetase HAMAP-Rule MF_00336
Dethiobiotin synthase HAMAP-Rule MF_00336
Gene names
Name:bioD HAMAP-Rule MF_00336
Ordered Locus Names:Patl_2554
OrganismPseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) [Complete proteome] [HAMAP] EMBL ABG41070.1
Taxonomic identifier342610 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas ›

Protein attributes

Sequence length287 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring By similarity. HAMAP-Rule MF_00336

Catalytic activity

ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. HAMAP-Rule MF_00336

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00336

Pathway

Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. HAMAP-Rule MF_00336

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00336.

Sequence similarities

Belongs to the dethiobiotin synthetase family. HAMAP-Rule MF_00336

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding170 – 1734ATP By similarity HAMAP-Rule MF_00336
Nucleotide binding235 – 2362ATP By similarity HAMAP-Rule MF_00336

Sites

Metal binding611Magnesium 1 By similarity HAMAP-Rule MF_00336
Metal binding651Magnesium 2 By similarity HAMAP-Rule MF_00336
Metal binding1031Magnesium 2 By similarity HAMAP-Rule MF_00336
Metal binding1701Magnesium 2 By similarity HAMAP-Rule MF_00336
Binding site1031ATP By similarity HAMAP-Rule MF_00336

Sequences

Sequence LengthMass (Da)Tools
Q15SR8 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: F9206BA82FABA364

FASTA28730,843
        10         20         30         40         50         60 
MSLDSPSTNQ RHLKSHQQSI SKNALQQGSS EYTPAEQTPS DQRPLKESKQ HAFFVTGTDT 

        70         80         90        100        110        120 
EVGKTFVSCA LLAACHDAGL STAAYKPVSA GCDVTQAGLR NEDALALQQA SNTPLSYDEV 

       130        140        150        160        170        180 
NPIAFAEPIA PHLACEKLMT KGQGAPIELD TINEGYVALI EKKSDMLLVE GAGGWRLPLG 

       190        200        210        220        230        240 
QNSQGQEQFL SDFAISQKLP VILVVGMRLG CINHALLTAQ SIEQDGLNVA GWVANMLEPE 

       250        260        270        280 
MPFLEENIHS LARLLNAPLI ARVPRAESPI AVKARINLSL LGVKKPD

« Hide

References

[1]"Complete sequence of Pseudoalteromonas atlantica T6c."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Karls A.C., Bartlett D., Higgins B.P., Richardson P.
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: T6c / ATCC BAA-1087.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000388 Genomic DNA. Translation: ABG41070.1.
RefSeqYP_662124.1. NC_008228.1.

3D structure databases

ProteinModelPortalQ15SR8.
ModBaseSearch...

Protein-protein interaction databases

STRING342610.Patl_2554.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG41070; ABG41070; Patl_2554.
GeneID4174309.
KEGGpat:Patl_2554.
PATRIC23050304. VBIPseAtl25434_2729.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0132.
HOGENOMHOG000275032.
KOK01935.
OMAREHGAPL.

Enzyme and pathway databases

BioCycPATL342610:GHGT-2638-MONOMER.
UniPathwayUPA00078; UER00161.

Family and domain databases

HAMAPMF_00336. BioD.
InterProIPR004472. DTB_synth_BioD.
[Graphical view]
TIGRFAMsTIGR00347. bioD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ15SR8_PSEA6
AccessionPrimary (citable) accession number: Q15SR8
Entry history
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: May 1, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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