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Q15Q03 (GLPK_PSEA6) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycerol kinase
EC=2.7.1.30
Alternative name(s):
ATP:glycerol 3-phosphotransferase
Glycerokinase
Short name=GK
Gene names
Name:glpK
Ordered Locus Names:Patl_3533
OrganismPseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) [Complete proteome] [HAMAP]
Taxonomic identifier342610 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas

Protein attributes

Sequence length497 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism. HAMAP MF_00186

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186

Sequence similarities

Belongs to the FGGY kinase family.

Ontologies

Keywords
   Biological processGlycerol metabolism
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycerol-3-phosphate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glycerol kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 497497Glycerol kinase HAMAP MF_00186
PRO_1000020757

Regions

Nucleotide binding410 – 4145ATP By similarity

Sites

Binding site141Substrate By similarity
Binding site181ATP By similarity
Binding site841Substrate By similarity
Binding site1361Substrate By similarity
Binding site2451Substrate By similarity
Binding site2671ATP By similarity
Binding site3101ATP; via carbonyl oxygen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q15Q03 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: E2B7FDE84F42DB2F

FASTA49753,962
        10         20         30         40         50         60 
MRIKDCILAI DQGTTSTRAI IFAPDSSIIA VAQQEFTQHY PNDGWVEHDP EDIWSSTVVV 

        70         80         90        100        110        120 
CRQAISEAIA KGARIAAIGV TNQRETTVVW DRNTGQAIYN AIVWQDRRTA KTCREMQDKG 

       130        140        150        160        170        180 
LFDVVNSRTG LLLDPYFSAS KVAWILDNVE GAREKADAGD LAFGTIDSFL IWRLTDGQVH 

       190        200        210        220        230        240 
ATDVTNASRT NLFNIHDMAW DPKLLEVFNV PKSVLPMVKE CADDFGHTTE DLFGFSLPIL 

       250        260        270        280        290        300 
GVAGDQQAAS IGQCCFKEGA IKSTYGTGCF VMLNTGTKAF NSKNKLLTTV AYTIKGETHY 

       310        320        330        340        350        360 
ALEGSIFIAG AAIQWLRDGL GVIKSASETE DLAKSLDDDH GVYMVPAFAG LGAPHWAPDA 

       370        380        390        400        410        420 
RGAVFGLTRG TTNAHFVRAA LESVCYQTSD LLHAMAEDGV SLDKIRVDGG MVGNNWLCQF 

       430        440        450        460        470        480 
LAGILDVTVE RPKIMETTAL GAAYLAGLKA GIYASCEQLA SMNEVESSFD AKMPSSQRRK 

       490 
LIAGWENAVQ STLGYTK

« Hide

References

[1]"Complete sequence of Pseudoalteromonas atlantica T6c."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Karls A.C., Bartlett D., Higgins B.P., Richardson P.
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: T6c / ATCC BAA-1087.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000388 Genomic DNA. Translation: ABG42035.1.
RefSeqYP_663089.1. NC_008228.1.

3D structure databases

ProteinModelPortalQ15Q03.
SMRQ15Q03. Positions 5-489.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ15Q03.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4175312.
GenomeReviewsGene locus Patl_3533 in contig CP000388_GR.
KEGGpat:Patl_3533.
NMPDRfig|342610.3.peg.315.
PATRIC23052402. VBIPseAtl25434_3752.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0554.
HOGENOMHBG511469.
OMACYQTRDL.
PhylomeDBQ15Q03.
ProtClustDBCLSK2398148.

Enzyme and pathway databases

BioCycPATL342610:PATL_3533-MONOMER.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
KOK00864.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. Glycerol_kin. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLPK_PSEA6
AccessionPrimary (citable) accession number: Q15Q03
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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