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Q15PV7 (Q15PV7_PSEA6) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Homoserine kinase HAMAP MF_00384
Short name=HK HAMAP MF_00384
Short name=HSK HAMAP MF_00384
EC=2.7.1.39 HAMAP MF_00384
Gene names
Name:thrB HAMAP MF_00384
Ordered Locus Names:Patl_3579
OrganismPseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) [Complete proteome] [HAMAP] EMBL ABG42081.1
Taxonomic identifier342610 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas

Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate By similarity. HAMAP MF_00384

Catalytic activity

ATP + L-homoserine = ADP + O-phospho-L-homoserine. HAMAP MF_00384

Pathway

Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. HAMAP MF_00384

Subcellular location

Cytoplasm By similarity HAMAP MF_00384.

Sequence similarities

Belongs to the GHMP kinase family. Homoserine kinase subfamily. HAMAP MF_00384

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Threonine biosynthesis HAMAP MF_00384
   Cellular componentCytoplasm HAMAP MF_00384
   LigandATP-binding HAMAP MF_00384
Nucleotide-binding
   Molecular functionKinase HAMAP MF_00384 EMBL ABG42081.1
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processthreonine biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

homoserine kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding105 – 11511ATP By similarity HAMAP MF_00384

Sequences

Sequence LengthMass (Da)Tools
Q15PV7 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: 73DE3A52408BEAF9

FASTA33135,818
        10         20         30         40         50         60 
MSELNDMMGK TLRAFAPAST GNVSLGFDLL GAALKPVDGT VLGDEVDLEL ADEFSLAVEG 

        70         80         90        100        110        120 
AFAHKLPADP DTNIVTRCYQ HFVKVMSEKG VELPPVKMTL HKHLPIGSGL GSSAASVVAA 

       130        140        150        160        170        180 
LHGLNEFYGQ LLGEVPFNQH ELLLIMGELE GQISGSVHYD NVAPCYLGGL TLMAEQADTL 

       190        200        210        220        230        240 
ALQLPTFKHW YWVACYSGIT VSTAAARDIL PKQVSMPNTL KFGRQLAVFV DALYRQDEKL 

       250        260        270        280        290        300 
AVSMMTDVIA EPYRKSLLPH FDESREFAMQ NGAMAFGISG SGPTVFAVCD NLEQAQTISS 

       310        320        330 
WLQENYIQND TGFSHVCQLD EQGAVAKDIS A

« Hide

References

[1]"Complete sequence of Pseudoalteromonas atlantica T6c."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Karls A.C., Bartlett D., Higgins B.P., Richardson P.
Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: T6c / ATCC BAA-1087.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000388 Genomic DNA. Translation: ABG42081.1.
RefSeqYP_663135.1. NC_008228.1.

3D structure databases

ProteinModelPortalQ15PV7.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ15PV7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4175359.
GenomeReviewsGene locus Patl_3579 in contig CP000388_GR.
KEGGpat:Patl_3579.
NMPDRfig|342610.3.peg.1700.
PATRIC23052504. VBIPseAtl25434_3802.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0083.
HOGENOMHBG646290.
OMAGSAHADN.
PhylomeDBQ15PV7.
ProtClustDBPRK01212.

Enzyme and pathway databases

BioCycPATL342610:PATL_3579-MONOMER.

Family and domain databases

HAMAPMF_00384. Homoser_kinase.
[Tree]
InterProIPR006204. GHMP_kinase.
IPR013750. GHMP_kinase_C.
IPR006203. GHMP_knse_ATP-bd_CS.
IPR000870. Homoserine_kinase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
Gene3DG3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KOK00872.
PfamPF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFPIRSF000676. Homoser_kin. 1 hit.
PRINTSPR00958. HOMSERKINASE.
SUPFAMSSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR00191. ThrB. 1 hit.
PROSITEPS00627. GHMP_KINASES_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ15PV7_PSEA6
AccessionPrimary (citable) accession number: Q15PV7
Entry history
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info