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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA), 6-phosphofructokinase (Patl_2592)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei353Proton donorUniRule annotation1
Active sitei384UniRule annotation1
Active sitei512UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciPATL342610:G1G6R-3751-MONOMER
UniPathwayiUPA00109; UER00181
UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Patl_3623
OrganismiPseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Taxonomic identifieri342610 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesPseudoalteromonadaceaePseudoalteromonas
Proteomesi
  • UP000001981 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000140001 – 547Glucose-6-phosphate isomeraseAdd BLAST547

Proteomic databases

PRIDEiQ15PR3

Interactioni

Protein-protein interaction databases

STRINGi342610.Patl_3623

Structurei

3D structure databases

ProteinModelPortaliQ15PR3
SMRiQ15PR3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QP8 Bacteria
COG0166 LUCA
HOGENOMiHOG000261370
KOiK01810
OMAiTNSQHAF
OrthoDBiPOG091H04C3

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q15PR3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTALTDTPTW QTLASLAEDV KQQHMRDWFA SDTSRASKYQ QTACGIELDF
60 70 80 90 100
SKNLITDDVL KALFALADES QVSQKRDAMF KGDIINHTEK RAVLHTALRN
110 120 130 140 150
FSGEPVYVDG QDVMPEVLAC QDKIKDFVAS IHSGERKGYT GKALKQIVSI
160 170 180 190 200
GIGGSFLGPK IMSEALKPYW FDGVKVHFVA NVDGCHIQDV LANLDHEETL
210 220 230 240 250
VVMSSKSFTT QETLQNTLTA KDWFLNAGGT QQDIAKHFIA VSSNIKAATD
260 270 280 290 300
FGMAEDNIFP MWDWVGGRYS LWSAIGLPIA LTLGYDNYRQ LLQGAFEMDE
310 320 330 340 350
HFKTAPAEQN LPMLTALLGV WYINFFGAQS HVLLPYYHYL RGFPAYVQQL
360 370 380 390 400
DMESNGKNIS GDTTAVDYAT GPIIWGSEGT NGQHSFHQLI HQGTLLIPAD
410 420 430 440 450
FMLPLNVPNQ DNTHHAMLAS NCFGQTQALM QGKTFDECYA DLEGKGLDEA
460 470 480 490 500
ERVKLATHKT MPGNKPSNTL LFEQMDPKTL GSLVAMYEHK VFVQGAIWGV
510 520 530 540
NSFDQWGVEL GKELGNQVLD KIVNTDAALG FDSSTNALIA RFRQANS
Length:547
Mass (Da):60,588
Last modified:July 25, 2006 - v1
Checksum:iB7A1B5D63C8759DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000388 Genomic DNA Translation: ABG42125.1
RefSeqiWP_011576349.1, NC_008228.1

Genome annotation databases

EnsemblBacteriaiABG42125; ABG42125; Patl_3623
KEGGipat:Patl_3623

Similar proteinsi

Entry informationi

Entry nameiG6PI_PSEA6
AccessioniPrimary (citable) accession number: Q15PR3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 25, 2006
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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