Q15MZ1 (PLSB_PSEA6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycerol-3-phosphate acyltransferase
Short name=GPAT
EC=2.3.1.15

Gene names

Name:	plsB
Ordered Locus Names:	Patl_4248

Organism

Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) [Complete proteome] [HAMAP]

Taxonomic identifier

342610 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas

Protein attributes

Sequence length	811 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate. HAMAP MF_00393
Pathway	Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3. HAMAP MF_00393
Subcellular location	Cell inner membrane; Peripheral membrane protein; Cytoplasmic side By similarity HAMAP MF_00393.
Domain	The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate By similarity. HAMAP MF_00393
Sequence similarities	Belongs to the GPAT/DAPAT family.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Cellular component	Cell inner membrane Cell membrane Membrane
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phospholipid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glycerol-3-phosphate O-acyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 811	811	Glycerol-3-phosphate acyltransferase HAMAP MF_00393		PRO_1000049441
Regions
	Motif	308 – 313	6	HXXXXD motif HAMAP MF_00393

Sequences

	Sequence		Length	Mass (Da)
	Q15MZ1 [UniParc]. Last modified July 25, 2006. Version 1. Checksum: 4DE8E797439DC370	FASTA	811	91,594
	10 20 30 40 50 60 MAWLHKLLLT MISVPLKWLV KVNSIPTDIA TELGIDNTKP IIYLLRTHSV TDQFALKMST 70 80 90 100 110 120 NSLGLPKPSE PVQIGGKELP ACLFLQQPRS LLTRKVKITK IADDVTRLFQ LHREHPELDL 130 140 150 160 170 180 QIVPVSIFWG RAPGRKLSGW SDIIANQVSP NWLRKFFIVL FLGRDNFVCY SKAVSSRTMA 190 200 210 220 230 240 DLKGSDEEIG HKLIRLAGTH FHRRRQNLIG PMLLERQELY NAVLGADSVR QAVSDEARSK 250 260 270 280 290 300 KQSNHQIQAK AKKYVDEIAA DYREGLVRIG DRLLTKIWNK VYNGIEVKHA DKVRALAQNG 310 320 330 340 350 360 HEIIYVPCHR SHMDYLLLTY VIYHEGLVTP HIAAGINLNF WPIGGILRKC GAFFLRRSFA 370 380 390 400 410 420 GNKLYTAVFR EYLELLFNKG YSVKYYPEGG RSRTGRLLPP KTGMLAMTLQ GLIKGINRPV 430 440 450 460 470 480 SIVPVYIGYE HVMEVSSYLK ELKGTDKKKE SFFQVFSAVR KLKNYGNGFL NFGDPINLSN 490 500 510 520 530 540 FLDSEVPDWR EAQNLEPDKK PRWLTPAVNT LANDVMGRIN QAAAVSGMSL CAMCLLSAKK 550 560 570 580 590 600 HAMAQDELER AIDDYLDLLK AAPYSDLSSI PELDGKALVE NTLKLNKLEV SQDSFGTIIS 610 620 630 640 650 660 LKRKNAVALT YYRNNILHLF ALPGLVSAIV FAHKGLARPQ VISLVGQLYP LLQRELFIYM 670 680 690 700 710 720 SHEEAMNYTD RLLSTMIDIG LLRAEDDTLC PPAATSKAFY SFWLLNRSIQ ETLQRYAAVL 730 740 750 760 770 780 TILKKEQTIG RGRLEKQSRE FAERLAALHG INSPEFFDKN VLSTFIHALK DNELINASSE 790 800 810 GQLQHSDTSE ALLASVEELI SPEITQRLQQ I

References

[1]

"Complete sequence of Pseudoalteromonas atlantica T6c." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Karls A.C., Bartlett D., Higgins B.P., Richardson P. Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: T6c / ATCC BAA-1087.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000388 Genomic DNA. Translation: ABG42747.1.
RefSeq	YP_663801.1. NC_008228.1.
3D structure databases
ProteinModelPortal	Q15MZ1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q15MZ1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4176038.
GenomeReviews	Gene locus Patl_4248 in contig CP000388_GR.
KEGG	pat:Patl_4248.
NMPDR	fig|342610.3.peg.1040.
PATRIC	23053958. VBIPseAtl25434_4519.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2937.
HOGENOM	HBG296590.
OMA	WNKLYQG.
ProtClustDB	CLSK2315973.
Enzyme and pathway databases
BioCyc	PATL342610:PATL_4248-MONOMER.
Family and domain databases
HAMAP	MF_00393. Glyc3P_acyltrans. [Tree]
InterPro	IPR002123. Acyltransferase. IPR022284. G3P_O-AcylTrfase. [Graphical view]
KO	K00631.
Pfam	PF01553. Acyltransferase. 1 hit. [Graphical view]
PIRSF	PIRSF000437. GPAT_DHAPAT. 1 hit.
SMART	SM00563. PlsC. 1 hit. [Graphical view]
TIGRFAMs	TIGR03703. PlsB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PLSB_PSEA6

Accession

Primary (citable) accession number: Q15MZ1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 25, 2006
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program