plsB

Functionⁱ

Catalytic activityⁱ

Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.UniRule annotation

Pathwayⁱ: CDP-diacylglycerol biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate.UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:

Glycerol-3-phosphate acyltransferase (plsB)
no protein annotated in this organism
Phosphatidate cytidylyltransferase (Patl_1254)

This subpathway is part of the pathway CDP-diacylglycerol biosynthesis, which is itself part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate, the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism.

GO - Molecular functionⁱ

glycerol-3-phosphate O-acyltransferase activity Source: UniProtKB-EC
sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity Source: UniProtKB-EC

Complete GO annotation...

GO - Biological processⁱ

CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway

Complete GO annotation...

Keywordsⁱ

Molecular function	Acyltransferase, Transferase
Biological process	Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

UniPathwayⁱ	UPA00557; UER00612.

UniPathwayⁱ

UPA00557; UER00612.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Glycerol-3-phosphate acyltransferaseUniRule annotation (EC:2.3.1.15UniRule annotation) Short name: GPATUniRule annotation
Gene namesⁱ	Name:plsBUniRule annotation Ordered Locus Names:Patl_4248
Organismⁱ	Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Taxonomic identifierⁱ	342610 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Pseudoalteromonadaceae › Pseudoalteromonas › Pseudoalteromonas atlantica
Proteomesⁱ	UP000001981 Componentⁱ: Chromosome

Subcellular locationⁱ

Cell inner membrane
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_00393
; Peripheral membrane protein
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_00393
; Cytoplasmic side
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_00393

GO - Cellular componentⁱ

plasma membrane Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

Cell inner membrane, Cell membrane, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_1000049441	1 – 811	Glycerol-3-phosphate acyltransferaseAdd BLAST		811

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	342610.Patl_4248.

STRINGⁱ

342610.Patl_4248.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q15MZ1.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	308 – 313	HXXXXD motif		6

Domainⁱ

The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.UniRule annotation

Sequence similaritiesⁱ

Belongs to the GPAT/DAPAT family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG4105E55. Bacteria. COG2937. LUCA.
HOGENOMⁱ	HOG000218231.
KEGG Orthology (KO) More...KOⁱ	K00631.
OMAⁱ	EVIYVPC.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H06BX.

Family and domain databases

HAMAPⁱ	MF_00393. Glyc3P_acyltrans. 1 hit.
InterProⁱ	View protein in InterPro IPR022284. GPAT/DHAPAT. IPR028354. GPAT_PlsB. IPR002123. Plipid/glycerol_acylTrfase.
PANTHERⁱ	PTHR12563. PTHR12563. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01553. Acyltransferase. 1 hit.
PIRSFⁱ	PIRSF500064. GPAT. 1 hit. PIRSF000437. GPAT_DHAPAT. 1 hit.
SMARTⁱ	View protein in SMART SM00563. PlsC. 1 hit.
TIGRFAMsⁱ	TIGR03703. plsB. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q15MZ1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAWLHKLLLT MISVPLKWLV KVNSIPTDIA TELGIDNTKP IIYLLRTHSV 
        60         70         80         90        100
TDQFALKMST NSLGLPKPSE PVQIGGKELP ACLFLQQPRS LLTRKVKITK 
       110        120        130        140        150
IADDVTRLFQ LHREHPELDL QIVPVSIFWG RAPGRKLSGW SDIIANQVSP 
       160        170        180        190        200
NWLRKFFIVL FLGRDNFVCY SKAVSSRTMA DLKGSDEEIG HKLIRLAGTH 
       210        220        230        240        250
FHRRRQNLIG PMLLERQELY NAVLGADSVR QAVSDEARSK KQSNHQIQAK 
       260        270        280        290        300
AKKYVDEIAA DYREGLVRIG DRLLTKIWNK VYNGIEVKHA DKVRALAQNG 
       310        320        330        340        350
HEIIYVPCHR SHMDYLLLTY VIYHEGLVTP HIAAGINLNF WPIGGILRKC 
       360        370        380        390        400
GAFFLRRSFA GNKLYTAVFR EYLELLFNKG YSVKYYPEGG RSRTGRLLPP 
       410        420        430        440        450
KTGMLAMTLQ GLIKGINRPV SIVPVYIGYE HVMEVSSYLK ELKGTDKKKE 
       460        470        480        490        500
SFFQVFSAVR KLKNYGNGFL NFGDPINLSN FLDSEVPDWR EAQNLEPDKK 
       510        520        530        540        550
PRWLTPAVNT LANDVMGRIN QAAAVSGMSL CAMCLLSAKK HAMAQDELER 
       560        570        580        590        600
AIDDYLDLLK AAPYSDLSSI PELDGKALVE NTLKLNKLEV SQDSFGTIIS 
       610        620        630        640        650
LKRKNAVALT YYRNNILHLF ALPGLVSAIV FAHKGLARPQ VISLVGQLYP 
       660        670        680        690        700
LLQRELFIYM SHEEAMNYTD RLLSTMIDIG LLRAEDDTLC PPAATSKAFY 
       710        720        730        740        750
SFWLLNRSIQ ETLQRYAAVL TILKKEQTIG RGRLEKQSRE FAERLAALHG 
       760        770        780        790        800
INSPEFFDKN VLSTFIHALK DNELINASSE GQLQHSDTSE ALLASVEELI 
       810 
SPEITQRLQQ I

Length:811

Mass (Da):91,594

Last modified:July 25, 2006 - v1

Checksum:ⁱ4DE8E797439DC370

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000388 Genomic DNA. Translation: ABG42747.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_011576933.1. NC_008228.1.

Genome annotation databases

EnsemblBacteriaⁱ	ABG42747; ABG42747; Patl_4248.
KEGGⁱ	pat:Patl_4248.

Similar proteinsⁱ

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
Q15MZ1	K6XLE2 F4AP17 K6ZLK7 K6ZD09 UPI000290EAE7	Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) Paraglaciecola agarilytica NO2 Glaciecola sp. (strain 4H-3-7+YE-5) Paraglaciecola polaris LMG 21857 Paraglaciecola mesophila KMM 241 Paraglaciecola chathamensis	811	UniRef90_Q15MZ1	Cluster: Glycerol-3-phosphate acyltransferase	6

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
Q15MZ1	K6ZLK7 UPI000290EAE7 F4AP17 K6ZD09 K6XLE2 A0A0U2PLK9 H5TAN8 UPI000871B589 K0D9W5 B4S1W8 +37	Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) Paraglaciecola polaris LMG 21857 Paraglaciecola chathamensis Glaciecola sp. (strain 4H-3-7+YE-5) Paraglaciecola mesophila KMM 241 Paraglaciecola agarilytica NO2 Lacimicrobium alkaliphilum Glaciecola punicea ACAM 611 Glaciecola punicea Alteromonas macleodii (strain Black Sea 11) And more	811	UniRef50_Q15MZ1	Cluster: Glycerol-3-phosphate acyltransferase	48

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CP000388 Genomic DNA. Translation: ABG42747.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_011576933.1. NC_008228.1.

3D structure databases

ProteinModelPortalⁱ	Q15MZ1.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	342610.Patl_4248.

STRINGⁱ

342610.Patl_4248.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	ABG42747; ABG42747; Patl_4248.
KEGGⁱ	pat:Patl_4248.

Phylogenomic databases

eggNOGⁱ	ENOG4105E55. Bacteria. COG2937. LUCA.
HOGENOMⁱ	HOG000218231.
KEGG Orthology (KO) More...KOⁱ	K00631.
OMAⁱ	EVIYVPC.
Database of Orthologous Groups More...OrthoDBⁱ	POG091H06BX.

Enzyme and pathway databases

UniPathwayⁱ	UPA00557; UER00612.

UniPathwayⁱ

UPA00557; UER00612.

Family and domain databases

HAMAPⁱ	MF_00393. Glyc3P_acyltrans. 1 hit.
InterProⁱ	View protein in InterPro IPR022284. GPAT/DHAPAT. IPR028354. GPAT_PlsB. IPR002123. Plipid/glycerol_acylTrfase.
PANTHERⁱ	PTHR12563. PTHR12563. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01553. Acyltransferase. 1 hit.
PIRSFⁱ	PIRSF500064. GPAT. 1 hit. PIRSF000437. GPAT_DHAPAT. 1 hit.
SMARTⁱ	View protein in SMART SM00563. PlsC. 1 hit.
TIGRFAMsⁱ	TIGR03703. plsB. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	PLSB_PSEA6
Accessionⁱ	Q15MZ1Primary (citable) accession number: Q15MZ1
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
	Last sequence update:	July 25, 2006
	Last modified:	August 30, 2017
	This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

UniProtKB

UniParc

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Proteomes

Annotation systems

Supporting data

UniProtKB - Q15MZ1 (PLSB_PSEA6)

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Glycerol-3-phosphate acyltransferase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: CDP-diacylglycerol biosynthesis

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

Pathwayⁱ: CDP-diacylglycerol biosynthesis

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ