Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q15JG1 (Q15JG1_STRHY) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:vldE EMBL ABC67269.1
OrganismStreptomyces hygroscopicus subsp. limoneus EMBL ABC67269.1
Taxonomic identifier264445 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length497 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding151Magnesium 1; via carbonyl oxygen PDB 3T7D
Metal binding551Magnesium 1 PDB 3T7D
Metal binding591Magnesium 1 PDB 3T7D
Metal binding1051Magnesium 2 PDB 3T7D
Metal binding1141Magnesium 4 PDB 3T5T
Metal binding1871Magnesium 3 PDB 3T5T
Metal binding2181Magnesium 4 PDB 3T5T
Metal binding2871Magnesium 3; via pros nitrogen PDB 3T5T
Metal binding2921Magnesium 2 PDB 3T7D
Metal binding3211Magnesium 3; via carbonyl oxygen PDB 3T5T
Metal binding3261Magnesium 2 PDB 3T7D
Metal binding4121Magnesium 4 PDB 3T5T
Binding site1141Chloride PDB 4F96 PDB 4F97
Binding site1871Chloride PDB 4F96 PDB 4F97

Sequences

Sequence LengthMass (Da)Tools
Q15JG1 [UniParc].

Last modified July 25, 2006. Version 1.
Checksum: 91CDAB5D51B859DC

FASTA49754,943
        10         20         30         40         50         60 
MTGSEIFLAS KRAAITYDTD PATGEPRAWL APGGTGNVVA EQAGVLNISW IASADSEDDR 

        70         80         90        100        110        120 
RASALNPDGV TMELHSGREI LVRLIRHDPA VFRNVQNFMT ANLMWAANNY GWDRWTQPSF 

       130        140        150        160        170        180 
GSDAREGWAD FGRFTRDFAD AILKSSAQSA DPVYLVHDYQ LVGVPALLRE QRPDAPILLF 

       190        200        210        220        230        240 
VHIPWPSADY WRILPKEIRT GILHGMLPAT TIGFFADRWC RNFLESVADL LPDARIDREA 

       250        260        270        280        290        300 
MTVEWRGHRT RLRTMPLGYS PLTLDGRNPQ LPEGIEEWAD GHRLVVHSGR TDPIKNAERA 

       310        320        330        340        350        360 
VRAFVLAARG GGLEKTRMLV RMNPNRLYVP ANADYVHRVE TAVAEANAEL GSDTVRIDND 

       370        380        390        400        410        420 
NDVNHTIACF RRADLLIFNS TVDGQNLSTF EAPLVNERDA DVILSETCGA AEVLGEYCRS 

       430        440        450        460        470        480 
VNPFDLVEQA EAISAALAAG PRQRAEAAAR RRDAARPWTL EAWVQAQLDG LAADHAARTA 

       490 
TAERFDTAPA VSTRADL 

« Hide

References

[1]"Genetic localization and heterologous expression of validamycin biosynthetic gene cluster isolated from Streptomyces hygroscopicus var. limoneus KCCM 11405 (IFO 12704)."
Singh D., Seo M.J., Kwon H.J., Rajkarnikar A., Kim K.R., Kim S.O., Suh J.W.
Gene 376:13-23(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: KCCM 11405 EMBL ABC67269.1.
[2]"Structural basis for the substrate specificity of ValL."
Zhang H., Zheng L., Qian H.
Submitted (JUL-2011) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 2-497 IN COMPLEX WITH MAGNESIUM.
[3]"Structural basis for the substrate specificity of ValL."
Zhang H., Zheng L., Qian H., Chen J.
Submitted (JUL-2011) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 2-497 IN COMPLEX WITH MAGNESIUM.
[4]"Mechanistic insights into validoxylamine A 7'-phosphate synthesis by VldE using the structure of the entire product complex."
Cavalier M.C., Yim Y.S., Asamizu S., Neau D., Almabruk K.H., Mahmud T., Lee Y.H.
PLoS ONE 7:e44934-e44934(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.11 ANGSTROMS) IN COMPLEX WITH CHLORIDE.
[5]"Crystal Structure of the VldE, the pseudo-glycosyltransferase, which catalyzes non-glycosidic C-N coupling in Validamycin A biosynthesis."
Cavalier M.C., Yim Y.-S., Asamizu S., Neau D., Mahmud T., Lee Y.-H.
Submitted (JAN-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.55 ANGSTROMS).
[6]"Crystal Structure of VldE, the pseudo-glycosyltransferase which catalyzes non-glycosidic C-N coupling in Validamycin A biosynthesis."
Cavalier M.C., Yim Y.-S., Asamizu S., Neau D., Mahmud T., Lee Y.-H.
Submitted (JAN-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.98 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ223652 Genomic DNA. Translation: ABC67269.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3T5TX-ray1.70A/B2-497[»]
3T7DX-ray1.70A/B2-497[»]
3VDMX-ray1.98A/B1-497[»]
3VDNX-ray2.55B1-497[»]
4F96X-ray2.15A/B1-497[»]
4F97X-ray2.11A/B1-497[»]
4F9FX-ray2.81A/B/C/D/E/F1-497[»]
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGT20. Glycosyltransferase Family 20.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-13774.

Family and domain databases

InterProIPR001830. Glyco_trans_20.
[Graphical view]
PfamPF00982. Glyco_transf_20. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ15JG1_STRHY
AccessionPrimary (citable) accession number: Q15JG1
Entry history
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: June 11, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)