SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q15JG1

- Q15JG1_STRHY

UniProt

Q15JG1 - Q15JG1_STRHY

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Putative glycosyltransferase

Gene
vldE
Organism
Streptomyces hygroscopicus subsp. limoneus
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi15 – 151Magnesium 1; via carbonyl oxygen
Metal bindingi55 – 551Magnesium 1
Metal bindingi59 – 591Magnesium 1
Metal bindingi105 – 1051Magnesium 2
Metal bindingi114 – 1141Magnesium 4Imported
Metal bindingi187 – 1871Magnesium 3Imported
Metal bindingi218 – 2181Magnesium 4Imported
Metal bindingi287 – 2871Magnesium 3; via pros nitrogenImported
Metal bindingi292 – 2921Magnesium 2
Metal bindingi321 – 3211Magnesium 3; via carbonyl oxygenImported
Metal bindingi326 – 3261Magnesium 2
Metal bindingi412 – 4121Magnesium 4Imported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. transferase activity Source: UniProtKB-KW

GO - Biological processi

  1. trehalose biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Keywords - Ligandi

MagnesiumImported, Metal-bindingImported

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-13774.

Protein family/group databases

CAZyiGT20. Glycosyltransferase Family 20.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative glycosyltransferaseImported
Gene namesi
Name:vldEImported
OrganismiStreptomyces hygroscopicus subsp. limoneusImported
Taxonomic identifieri264445 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3T5TX-ray1.70A/B2-497[»]
3T7DX-ray1.70A/B2-497[»]
3VDMX-ray1.98A/B1-497[»]
3VDNX-ray2.55B1-497[»]
4F96X-ray2.15A/B1-497[»]
4F97X-ray2.11A/B1-497[»]
4F9FX-ray2.81A/B/C/D/E/F1-497[»]

Family & Domainsi

Family and domain databases

InterProiIPR001830. Glyco_trans_20.
[Graphical view]
PfamiPF00982. Glyco_transf_20. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q15JG1-1 [UniParc]FASTAAdd to Basket

« Hide

MTGSEIFLAS KRAAITYDTD PATGEPRAWL APGGTGNVVA EQAGVLNISW    50
IASADSEDDR RASALNPDGV TMELHSGREI LVRLIRHDPA VFRNVQNFMT 100
ANLMWAANNY GWDRWTQPSF GSDAREGWAD FGRFTRDFAD AILKSSAQSA 150
DPVYLVHDYQ LVGVPALLRE QRPDAPILLF VHIPWPSADY WRILPKEIRT 200
GILHGMLPAT TIGFFADRWC RNFLESVADL LPDARIDREA MTVEWRGHRT 250
RLRTMPLGYS PLTLDGRNPQ LPEGIEEWAD GHRLVVHSGR TDPIKNAERA 300
VRAFVLAARG GGLEKTRMLV RMNPNRLYVP ANADYVHRVE TAVAEANAEL 350
GSDTVRIDND NDVNHTIACF RRADLLIFNS TVDGQNLSTF EAPLVNERDA 400
DVILSETCGA AEVLGEYCRS VNPFDLVEQA EAISAALAAG PRQRAEAAAR 450
RRDAARPWTL EAWVQAQLDG LAADHAARTA TAERFDTAPA VSTRADL 497
Length:497
Mass (Da):54,943
Last modified:July 25, 2006 - v1
Checksum:i91CDAB5D51B859DC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ223652 Genomic DNA. Translation: ABC67269.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DQ223652 Genomic DNA. Translation: ABC67269.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3T5T X-ray 1.70 A/B 2-497 [» ]
3T7D X-ray 1.70 A/B 2-497 [» ]
3VDM X-ray 1.98 A/B 1-497 [» ]
3VDN X-ray 2.55 B 1-497 [» ]
4F96 X-ray 2.15 A/B 1-497 [» ]
4F97 X-ray 2.11 A/B 1-497 [» ]
4F9F X-ray 2.81 A/B/C/D/E/F 1-497 [» ]
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GT20. Glycosyltransferase Family 20.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

BioCyci MetaCyc:MONOMER-13774.

Family and domain databases

InterProi IPR001830. Glyco_trans_20.
[Graphical view ]
Pfami PF00982. Glyco_transf_20. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genetic localization and heterologous expression of validamycin biosynthetic gene cluster isolated from Streptomyces hygroscopicus var. limoneus KCCM 11405 (IFO 12704)."
    Singh D., Seo M.J., Kwon H.J., Rajkarnikar A., Kim K.R., Kim S.O., Suh J.W.
    Gene 376:13-23(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: KCCM 11405Imported.
  2. "Structural basis for the substrate specificity of ValL."
    Zhang H., Zheng L., Qian H.
    Submitted (JUL-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 2-497 IN COMPLEX WITH MAGNESIUM.
  3. "Structural basis for the substrate specificity of ValL."
    Zhang H., Zheng L., Qian H., Chen J.
    Submitted (JUL-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 2-497 IN COMPLEX WITH MAGNESIUM.
  4. "Mechanistic insights into validoxylamine A 7'-phosphate synthesis by VldE using the structure of the entire product complex."
    Cavalier M.C., Yim Y.S., Asamizu S., Neau D., Almabruk K.H., Mahmud T., Lee Y.H.
    PLoS ONE 7:e44934-e44934(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.11 ANGSTROMS).
  5. "Crystal Structure of the VldE, the pseudo-glycosyltransferase, which catalyzes non-glycosidic C-N coupling in Validamycin A biosynthesis."
    Cavalier M.C., Yim Y.-S., Asamizu S., Neau D., Mahmud T., Lee Y.-H.
    Submitted (JAN-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.55 ANGSTROMS).
  6. "Crystal Structure of VldE, the pseudo-glycosyltransferase which catalyzes non-glycosidic C-N coupling in Validamycin A biosynthesis."
    Cavalier M.C., Yim Y.-S., Asamizu S., Neau D., Mahmud T., Lee Y.-H.
    Submitted (JAN-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.98 ANGSTROMS).

Entry informationi

Entry nameiQ15JG1_STRHY
AccessioniPrimary (citable) accession number: Q15JG1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 25, 2006
Last sequence update: July 25, 2006
Last modified: September 3, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

Similar proteinsi