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Q15833

- STXB2_HUMAN

UniProt

Q15833 - STXB2_HUMAN

Protein

Syntaxin-binding protein 2

Gene

STXBP2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 120 (01 Oct 2014)
      Sequence version 2 (30 Nov 2010)
      Previous versions | rss
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    Functioni

    Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells.2 Publications

    GO - Molecular functioni

    1. protein binding Source: UniProtKB
    2. syntaxin-3 binding Source: UniProtKB

    GO - Biological processi

    1. leukocyte mediated cytotoxicity Source: UniProtKB
    2. neutrophil degranulation Source: UniProtKB
    3. protein transport Source: UniProtKB-KW
    4. regulation of mast cell degranulation Source: UniProtKB
    5. vesicle docking involved in exocytosis Source: InterPro

    Keywords - Biological processi

    Exocytosis, Protein transport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Syntaxin-binding protein 2
    Alternative name(s):
    Protein unc-18 homolog 2
    Short name:
    Unc18-2
    Protein unc-18 homolog B
    Short name:
    Unc-18B
    Gene namesi
    Name:STXBP2
    Synonyms:UNC18B
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 19

    Organism-specific databases

    HGNCiHGNC:11445. STXBP2.

    Subcellular locationi

    GO - Cellular componenti

    1. apical plasma membrane Source: Ensembl
    2. azurophil granule Source: UniProtKB
    3. cytolytic granule Source: UniProtKB
    4. cytosol Source: UniProtKB
    5. extracellular vesicular exosome Source: UniProtKB
    6. plasma membrane Source: UniProtKB
    7. specific granule Source: UniProtKB
    8. tertiary granule Source: UniProtKB

    Pathology & Biotechi

    Involvement in diseasei

    Familial hemophagocytic lymphohistiocytosis 5 (FHL5) [MIM:613101]: A rare disorder characterized by immune dysregulation with hypercytokinemia, defective function of natural killer cell, and massive infiltration of several organs by activated lymphocytes and macrophages. The clinical features of the disease include fever, hepatosplenomegaly, cytopenia, and less frequently neurological abnormalities ranging from irritability and hypotonia to seizures, cranial nerve deficits and ataxia.2 Publications
    Note: The disease is caused by mutations affecting the gene represented in this entry.
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti209 – 2091L → P in FHL5. 1 Publication
    VAR_063814
    Natural varianti232 – 2321Missing in FHL5; leads to a complete loss of the ability to interact with STX11. 1 Publication
    VAR_063815
    Natural varianti292 – 2921R → H in FHL5; leads to a complete loss of the ability to interact with STX11. 1 Publication
    VAR_063816
    Natural varianti405 – 4051R → Q in FHL5; leads to a complete loss of the ability to interact with STX11. 1 Publication
    VAR_063817
    Natural varianti405 – 4051R → W in FHL5; leads to a complete loss of the ability to interact with STX11. 1 Publication
    VAR_063818
    Natural varianti477 – 4771P → L in FHL5; leads to a complete loss of the ability to interact with STX11. 2 Publications
    VAR_063819

    Keywords - Diseasei

    Disease mutation

    Organism-specific databases

    MIMi613101. phenotype.
    Orphaneti540. Familial hemophagocytic lymphohistiocytosis.
    PharmGKBiPA36242.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 593593Syntaxin-binding protein 2PRO_0000206281Add
    BLAST

    Proteomic databases

    MaxQBiQ15833.
    PaxDbiQ15833.
    PRIDEiQ15833.

    2D gel databases

    OGPiQ15833.

    PTM databases

    PhosphoSiteiQ15833.

    Expressioni

    Tissue specificityi

    Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.

    Gene expression databases

    ArrayExpressiQ15833.
    BgeeiQ15833.
    CleanExiHS_STXBP2.
    GenevestigatoriQ15833.

    Organism-specific databases

    HPAiHPA015564.

    Interactioni

    Subunit structurei

    Interacts with STX1A, STX2 and STX3 By similarity. Interacts with STX11.By similarity2 Publications

    Protein-protein interaction databases

    BioGridi112682. 5 interactions.
    IntActiQ15833. 1 interaction.
    MINTiMINT-4718353.
    STRINGi9606.ENSP00000221283.

    Structurei

    Secondary structure

    1
    593
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi6 – 1510
    Turni16 – 227
    Beta strandi29 – 335
    Helixi35 – 428
    Helixi47 – 515
    Turni52 – 543
    Beta strandi55 – 584
    Beta strandi71 – 777
    Helixi81 – 899
    Beta strandi102 – 1087
    Helixi112 – 1198
    Helixi123 – 1264
    Beta strandi127 – 1326
    Beta strandi141 – 1466
    Helixi152 – 1576
    Helixi159 – 1646
    Helixi165 – 18218
    Beta strandi188 – 1914
    Beta strandi193 – 1953
    Helixi196 – 21520
    Turni217 – 2204
    Helixi225 – 2273
    Beta strandi229 – 2335
    Helixi235 – 2373
    Helixi241 – 2433
    Helixi249 – 2568
    Beta strandi263 – 2675
    Beta strandi276 – 2805
    Beta strandi282 – 2843
    Helixi286 – 2916
    Turni296 – 2983
    Helixi299 – 31416
    Helixi327 – 3315
    Helixi333 – 35725
    Helixi360 – 37314
    Helixi385 – 3939
    Helixi400 – 41415
    Helixi419 – 42810
    Helixi432 – 4343
    Helixi435 – 4395
    Helixi440 – 4434
    Helixi478 – 48710
    Turni493 – 4953
    Beta strandi498 – 5003
    Beta strandi533 – 5386
    Helixi544 – 55613
    Turni557 – 5593
    Beta strandi562 – 5709
    Helixi573 – 58210

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4CCAX-ray2.60A1-593[»]
    ProteinModelPortaliQ15833.
    SMRiQ15833. Positions 5-593.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the STXBP/unc-18/SEC1 family.Curated

    Phylogenomic databases

    eggNOGiCOG5158.
    HOGENOMiHOG000232146.
    HOVERGENiHBG052710.
    InParanoidiQ15833.
    KOiK15300.
    OMAiHIADVTK.
    OrthoDBiEOG78PV8M.
    PhylomeDBiQ15833.
    TreeFamiTF313242.

    Family and domain databases

    Gene3Di3.40.50.1910. 2 hits.
    InterProiIPR027482. Sec-1-like_dom2.
    IPR001619. Sec1-like.
    [Graphical view]
    PANTHERiPTHR11679. PTHR11679. 1 hit.
    PfamiPF00995. Sec1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF005715. VPS45_Sec1. 1 hit.
    SUPFAMiSSF56815. SSF56815. 1 hit.

    Sequences (3)i

    Sequence statusi: Complete.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q15833-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MAPSGLKAVV GEKILSGVIR SVKKDGEWKV LIMDHPSMRI LSSCCKMSDI    50
    LAEGITIVED INKRREPIPS LEAIYLLSPT EKSVQALIKD FQGTPTFTYK 100
    AAHIFFTDTC PEPLFSELGR SRLAKVVKTL KEIHLAFLPY EAQVFSLDAP 150
    HSTYNLYCPF RAEERTRQLE VLAQQIATLC ATLQEYPAIR YRKGPEDTAQ 200
    LAHAVLAKLN AFKADTPSLG EGPEKTRSQL LIMDRAADPV SPLLHELTFQ 250
    AMAYDLLDIE QDTYRYETTG LSEAREKAVL LDEDDDLWVE LRHMHIADVS 300
    KKVTELLRTF CESKRLTTDK ANIKDLSQIL KKMPQYQKEL NKYSTHLHLA 350
    DDCMKHFKGS VEKLCSVEQD LAMGSDAEGE KIKDSMKLIV PVLLDAAVPA 400
    YDKIRVLLLY ILLRNGVSEE NLAKLIQHAN VQAHSSLIRN LEQLGGTVTN 450
    PGGSGTSSRL EPRERMEPTY QLSRWTPVIK DVMEDAVEDR LDRNLWPFVS 500
    DPAPTASSQA AVSARFGHWH KNKAGIEARA GPRLIVYVMG GVAMSEMRAA 550
    YEVTRATEGK WEVLIGSSHI LTPTRFLDDL KALDKKLEDI ALP 593
    Length:593
    Mass (Da):66,453
    Last modified:November 30, 2010 - v2
    Checksum:i98E27B55309168A9
    GO
    Isoform 2 (identifier: Q15833-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         83-85: Missing.

    Show »
    Length:590
    Mass (Da):66,138
    Checksum:iC9A58E0240FCF3B2
    GO
    Isoform 3 (identifier: Q15833-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         82-82: K → KAQAQRVIHLPQ

    Note: No experimental confirmation available.

    Show »
    Length:604
    Mass (Da):67,695
    Checksum:i66F535E773C359DC
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti348 – 3481H → R in BAG64687. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti209 – 2091L → P in FHL5. 1 Publication
    VAR_063814
    Natural varianti232 – 2321Missing in FHL5; leads to a complete loss of the ability to interact with STX11. 1 Publication
    VAR_063815
    Natural varianti292 – 2921R → H in FHL5; leads to a complete loss of the ability to interact with STX11. 1 Publication
    VAR_063816
    Natural varianti405 – 4051R → Q in FHL5; leads to a complete loss of the ability to interact with STX11. 1 Publication
    VAR_063817
    Natural varianti405 – 4051R → W in FHL5; leads to a complete loss of the ability to interact with STX11. 1 Publication
    VAR_063818
    Natural varianti477 – 4771P → L in FHL5; leads to a complete loss of the ability to interact with STX11. 2 Publications
    VAR_063819
    Natural varianti526 – 5261I → V.2 Publications
    Corresponds to variant rs6791 [ dbSNP | Ensembl ].
    VAR_014934

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei82 – 821K → KAQAQRVIHLPQ in isoform 3. 1 PublicationVSP_055157
    Alternative sequencei83 – 853Missing in isoform 2. 2 PublicationsVSP_040121

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U63533 mRNA. Translation: AAC50762.1.
    BT006915 mRNA. Translation: AAP35561.1.
    AK303701 mRNA. Translation: BAG64687.1.
    AC008763 Genomic DNA. No translation available.
    CH471139 Genomic DNA. Translation: EAW69018.1.
    BC002869 mRNA. Translation: AAH02869.1.
    CCDSiCCDS12181.1. [Q15833-1]
    CCDS45948.1. [Q15833-2]
    CCDS62522.1. [Q15833-3]
    RefSeqiNP_001120868.1. NM_001127396.2. [Q15833-2]
    NP_001258963.1. NM_001272034.1.
    NP_008880.2. NM_006949.3. [Q15833-1]
    UniGeneiHs.515104.

    Genome annotation databases

    GeneIDi6813.
    KEGGihsa:6813.
    UCSCiuc002mha.5. human. [Q15833-1]
    uc002mhb.5. human. [Q15833-2]

    Polymorphism databases

    DMDMi313104015.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U63533 mRNA. Translation: AAC50762.1 .
    BT006915 mRNA. Translation: AAP35561.1 .
    AK303701 mRNA. Translation: BAG64687.1 .
    AC008763 Genomic DNA. No translation available.
    CH471139 Genomic DNA. Translation: EAW69018.1 .
    BC002869 mRNA. Translation: AAH02869.1 .
    CCDSi CCDS12181.1. [Q15833-1 ]
    CCDS45948.1. [Q15833-2 ]
    CCDS62522.1. [Q15833-3 ]
    RefSeqi NP_001120868.1. NM_001127396.2. [Q15833-2 ]
    NP_001258963.1. NM_001272034.1.
    NP_008880.2. NM_006949.3. [Q15833-1 ]
    UniGenei Hs.515104.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4CCA X-ray 2.60 A 1-593 [» ]
    ProteinModelPortali Q15833.
    SMRi Q15833. Positions 5-593.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 112682. 5 interactions.
    IntActi Q15833. 1 interaction.
    MINTi MINT-4718353.
    STRINGi 9606.ENSP00000221283.

    PTM databases

    PhosphoSitei Q15833.

    Polymorphism databases

    DMDMi 313104015.

    2D gel databases

    OGPi Q15833.

    Proteomic databases

    MaxQBi Q15833.
    PaxDbi Q15833.
    PRIDEi Q15833.

    Protocols and materials databases

    DNASUi 6813.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 6813.
    KEGGi hsa:6813.
    UCSCi uc002mha.5. human. [Q15833-1 ]
    uc002mhb.5. human. [Q15833-2 ]

    Organism-specific databases

    CTDi 6813.
    GeneCardsi GC19P007701.
    GeneReviewsi STXBP2.
    H-InvDB HIX0021726.
    HGNCi HGNC:11445. STXBP2.
    HPAi HPA015564.
    MIMi 601717. gene.
    613101. phenotype.
    neXtProti NX_Q15833.
    Orphaneti 540. Familial hemophagocytic lymphohistiocytosis.
    PharmGKBi PA36242.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG5158.
    HOGENOMi HOG000232146.
    HOVERGENi HBG052710.
    InParanoidi Q15833.
    KOi K15300.
    OMAi HIADVTK.
    OrthoDBi EOG78PV8M.
    PhylomeDBi Q15833.
    TreeFami TF313242.

    Miscellaneous databases

    GeneWikii Syntaxin_binding_protein_2.
    GenomeRNAii 6813.
    NextBioi 26589.
    PROi Q15833.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q15833.
    Bgeei Q15833.
    CleanExi HS_STXBP2.
    Genevestigatori Q15833.

    Family and domain databases

    Gene3Di 3.40.50.1910. 2 hits.
    InterProi IPR027482. Sec-1-like_dom2.
    IPR001619. Sec1-like.
    [Graphical view ]
    PANTHERi PTHR11679. PTHR11679. 1 hit.
    Pfami PF00995. Sec1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF005715. VPS45_Sec1. 1 hit.
    SUPFAMi SSF56815. SSF56815. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT VAL-526.
    2. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
      Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), VARIANT VAL-526.
      Tissue: Kidney.
    4. "The DNA sequence and biology of human chromosome 19."
      Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
      , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
      Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Lung.
    7. "Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11."
      zur Stadt U., Rohr J., Seifert W., Koch F., Grieve S., Pagel J., Strauss J., Kasper B., Nuernberg G., Becker C., Maul-Pavicic A., Beutel K., Janka G., Griffiths G., Ehl S., Hennies H.C.
      Am. J. Hum. Genet. 85:482-492(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH STX11, VARIANTS FHL5 PRO-209; ILE-232 DEL; HIS-292; TRP-405; GLN-405 AND LEU-477, CHARACTERIZATION OF VARIANTS FHL5 ILE-232 DEL; HIS-292; TRP-405; GLN-405 AND LEU-477.
    8. "Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells."
      Cote M., Menager M.M., Burgess A., Mahlaoui N., Picard C., Schaffner C., Al-Manjomi F., Al-Harbi M., Alangari A., Le Deist F., Gennery A.R., Prince N., Cariou A., Nitschke P., Blank U., El-Ghazali G., Menasche G., Latour S., Fischer A., de Saint Basile G.
      J. Clin. Invest. 119:3765-3773(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH STX11, VARIANT FHL5 LEU-477.
    9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    10. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiSTXB2_HUMAN
    AccessioniPrimary (citable) accession number: Q15833
    Secondary accession number(s): B4E175, E7EQD5, Q9BU65
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 30, 2010
    Last modified: October 1, 2014
    This is version 120 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3