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Q15735

- PI5PA_HUMAN

UniProt

Q15735 - PI5PA_HUMAN

Protein

Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A

Gene

INPP5J

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 127 (01 Oct 2014)
      Sequence version 3 (17 Oct 2006)
      Previous versions | rss
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    Functioni

    Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles By similarity.By similarity

    Catalytic activityi

    D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate.
    1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.

    GO - Molecular functioni

    1. inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity Source: UniProtKB-EC
    2. inositol-1,4,5-trisphosphate 5-phosphatase activity Source: UniProtKB-EC
    3. inositol-polyphosphate 5-phosphatase activity Source: UniProtKB-EC
    4. phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity Source: Ensembl

    GO - Biological processi

    1. inositol phosphate metabolic process Source: Reactome
    2. negative regulation of microtubule polymerization Source: Ensembl
    3. negative regulation of neuron projection development Source: Ensembl
    4. negative regulation of peptidyl-serine phosphorylation Source: Ensembl
    5. phosphatidylinositol biosynthetic process Source: Reactome
    6. phosphatidylinositol dephosphorylation Source: InterPro
    7. phospholipid metabolic process Source: Reactome
    8. small molecule metabolic process Source: Reactome

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciMetaCyc:HS11950-MONOMER.
    ReactomeiREACT_121025. Synthesis of PIPs at the plasma membrane.
    REACT_150312. Synthesis of IP3 and IP4 in the cytosol.
    REACT_150352. Synthesis of IP2, IP, and Ins in the cytosol.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC:3.1.3.56)
    Alternative name(s):
    Inositol polyphosphate 5-phosphatase J
    Gene namesi
    Name:INPP5J
    Synonyms:PIB5PA, PIPP
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 22

    Organism-specific databases

    HGNCiHGNC:8956. INPP5J.

    Subcellular locationi

    Cytoplasm By similarity
    Note: Predominantly localized to membrane ruffles.By similarity

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. cytosol Source: Reactome
    3. dendritic shaft Source: Ensembl
    4. growth cone Source: Ensembl
    5. plasma membrane Source: Ensembl
    6. ruffle Source: MGI

    Keywords - Cellular componenti

    Cytoplasm

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA164720918.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 10061006Phosphatidylinositol 4,5-bisphosphate 5-phosphatase APRO_0000209738Add
    BLAST

    Proteomic databases

    MaxQBiQ15735.
    PaxDbiQ15735.
    PRIDEiQ15735.

    PTM databases

    PhosphoSiteiQ15735.

    Expressioni

    Gene expression databases

    ArrayExpressiQ15735.
    BgeeiQ15735.
    CleanExiHS_INPP5J.
    GenevestigatoriQ15735.

    Organism-specific databases

    HPAiHPA034539.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000384534.

    Structurei

    3D structure databases

    ProteinModelPortaliQ15735.
    SMRiQ15735. Positions 423-728.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni425 – 728304CatalyticSequence AnalysisAdd
    BLAST
    Regioni729 – 840112Required for ruffle localizationBy similarityAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi102 – 1076RSXSXX motif 1
    Motifi345 – 3506SH3-bindingSequence Analysis
    Motifi350 – 3556RSXSXX motif 2
    Motifi874 – 8796RSXSXX motif 3
    Motifi885 – 8906RSXSXX motif 4
    Motifi911 – 9166RSXSXX motif 5

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi122 – 371250Pro-richAdd
    BLAST
    Compositional biasi840 – 93798Ser-richAdd
    BLAST

    Domaini

    The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein.

    Sequence similaritiesi

    Keywords - Domaini

    Repeat, SH3-binding

    Phylogenomic databases

    eggNOGiCOG5411.
    HOGENOMiHOG000046051.
    HOVERGENiHBG082135.
    InParanoidiQ15735.
    KOiK01106.
    OMAiNIYQVTF.
    OrthoDBiEOG789CB4.
    PhylomeDBiQ15735.
    TreeFamiTF317034.

    Family and domain databases

    Gene3Di3.60.10.10. 1 hit.
    InterProiIPR005135. Endo/exonuclease/phosphatase.
    IPR000300. IPPc.
    [Graphical view]
    PfamiPF03372. Exo_endo_phos. 1 hit.
    [Graphical view]
    SMARTiSM00128. IPPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56219. SSF56219. 1 hit.

    Sequences (3)i

    Sequence statusi: Complete.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q15735-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MEGQSSRGSR RPGTRAGLGS LPMPQGVAQT GAPSKVDSSF QLPAKKNAAL     50
    GPSEPRLALA PVGPRAAMSA SSEGPRLALA SPRPILAPLC TPEGQKTATA 100
    HRSSSLAPTS VGQLVMSASA GPKPPPATTG SVLAPTSLGL VMPASAGPRS 150
    PPVTLGPNLA PTSRDQKQEP PASVGPKPTL AASGLSLALA SEEQPPELPS 200
    TPSPVPSPVL SPTQEQALAP ASTASGAASV GQTSARKRDA PAPRPLPASE 250
    GHLQPPAQTS GPTGSPPCIQ TSPDPRLSPS FRARPEALHS SPEDPVLPRP 300
    PQTLPLDVGQ GPSEPGTHSP GLLSPTFRPG APSGQTVPPP LPKPPRSPSR 350
    SPSHSPNRSP CVPPAPDMAL PRLGTQSTGP GRCLSPNLQA QEAPAPVTTS 400
    SSTSTLSSSP WSAQPTWKSD PGFRITVVTW NVGTAMPPDD VTSLLHLGGG 450
    DDSDGADMIA IGLQEVNSML NKRLKDALFT DQWSELFMDA LGPFNFVLVS 500
    SVRMQGVILL LFAKYYHLPF LRDVQTDCTR TGLGGYWGNK GGVSVRLAAF 550
    GHMLCFLNCH LPAHMDKAEQ RKDNFQTILS LQQFQGPGAQ GILDHDLVFW 600
    FGDLNFRIES YDLHFVKFAI DSDQLHQLWE KDQLNMAKNT WPILKGFQEG 650
    PLNFAPTFKF DVGTNKYDTS AKKRKPAWTD RILWKVKAPG GGPSPSGRKS 700
    HRLQVTQHSY RSHMEYTVSD HKPVAAQFLL QFAFRDDMPL VRLEVADEWV 750
    RPEQAVVRYR METVFARSSW DWIGLYRVGF RHCKDYVAYV WAKHEDVDGN 800
    TYQVTFSEES LPKGHGDFIL GYYSHNHSIL IGITEPFQIS LPSSELASSS 850
    TDSSGTSSEG EDDSTLELLA PKSRSPSPGK SKRHRSRSPG LARFPGLALR 900
    PSSRERRGAS RSPSPQSRRL SRVAPDRSSN GSSRGSSEEG PSGLPGPWAF 950
    PPAVPRSLGL LPALRLETVD PGGGGSWGPD REALAPNSLS PSPQGHRGLE 1000
    EGGLGP 1006
    Length:1,006
    Mass (Da):107,197
    Last modified:October 17, 2006 - v3
    Checksum:iADB6382AA33E15AC
    GO
    Isoform 2 (identifier: Q15735-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-367: Missing.

    Show »
    Length:639
    Mass (Da):70,464
    Checksum:i3ED5CD8BBB3398D0
    GO
    Isoform 3 (identifier: Q15735-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         56-423: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:638
    Mass (Da):70,239
    Checksum:i3F8ECF77ECC71C26
    GO

    Sequence cautioni

    The sequence AAD15618.1 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti610 – 6123SYD → ARG1 PublicationCurated
    Sequence conflicti662 – 6621V → A in BAC86611. (PubMed:14702039)Curated
    Sequence conflicti791 – 7911W → R in AAI09289. (PubMed:15489334)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti333 – 3331S → I.
    Corresponds to variant rs12485025 [ dbSNP | Ensembl ].
    VAR_028107

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 367367Missing in isoform 2. 2 PublicationsVSP_007296Add
    BLAST
    Alternative sequencei56 – 423368Missing in isoform 3. 1 PublicationVSP_021017Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK092859 mRNA. Translation: BAG52616.1.
    AK095944 mRNA. Translation: BAC04657.1.
    AK126610 mRNA. Translation: BAC86611.1.
    AC005005 Genomic DNA. Translation: AAD15618.1. Sequence problems.
    CH471095 Genomic DNA. Translation: EAW59936.1.
    BC109288 mRNA. Translation: AAI09289.1.
    U45975 mRNA. Translation: AAB03216.1.
    CCDSiCCDS46687.1. [Q15735-3]
    CCDS63453.1. [Q15735-1]
    CCDS63455.1. [Q15735-2]
    RefSeqiNP_001002837.1. NM_001002837.2. [Q15735-3]
    NP_001271214.1. NM_001284285.1. [Q15735-1]
    NP_001271217.1. NM_001284288.1. [Q15735-2]
    NP_001271218.1. NM_001284289.1. [Q15735-2]
    UniGeneiHs.517549.

    Genome annotation databases

    EnsembliENST00000331075; ENSP00000333262; ENSG00000185133. [Q15735-1]
    ENST00000400294; ENSP00000383150; ENSG00000185133. [Q15735-2]
    ENST00000404390; ENSP00000384534; ENSG00000185133. [Q15735-3]
    ENST00000405300; ENSP00000384596; ENSG00000185133. [Q15735-2]
    GeneIDi27124.
    KEGGihsa:27124.
    UCSCiuc003ajs.4. human. [Q15735-1]
    uc003ajt.4. human. [Q15735-3]

    Polymorphism databases

    DMDMi116242713.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK092859 mRNA. Translation: BAG52616.1 .
    AK095944 mRNA. Translation: BAC04657.1 .
    AK126610 mRNA. Translation: BAC86611.1 .
    AC005005 Genomic DNA. Translation: AAD15618.1 . Sequence problems.
    CH471095 Genomic DNA. Translation: EAW59936.1 .
    BC109288 mRNA. Translation: AAI09289.1 .
    U45975 mRNA. Translation: AAB03216.1 .
    CCDSi CCDS46687.1. [Q15735-3 ]
    CCDS63453.1. [Q15735-1 ]
    CCDS63455.1. [Q15735-2 ]
    RefSeqi NP_001002837.1. NM_001002837.2. [Q15735-3 ]
    NP_001271214.1. NM_001284285.1. [Q15735-1 ]
    NP_001271217.1. NM_001284288.1. [Q15735-2 ]
    NP_001271218.1. NM_001284289.1. [Q15735-2 ]
    UniGenei Hs.517549.

    3D structure databases

    ProteinModelPortali Q15735.
    SMRi Q15735. Positions 423-728.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000384534.

    PTM databases

    PhosphoSitei Q15735.

    Polymorphism databases

    DMDMi 116242713.

    Proteomic databases

    MaxQBi Q15735.
    PaxDbi Q15735.
    PRIDEi Q15735.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000331075 ; ENSP00000333262 ; ENSG00000185133 . [Q15735-1 ]
    ENST00000400294 ; ENSP00000383150 ; ENSG00000185133 . [Q15735-2 ]
    ENST00000404390 ; ENSP00000384534 ; ENSG00000185133 . [Q15735-3 ]
    ENST00000405300 ; ENSP00000384596 ; ENSG00000185133 . [Q15735-2 ]
    GeneIDi 27124.
    KEGGi hsa:27124.
    UCSCi uc003ajs.4. human. [Q15735-1 ]
    uc003ajt.4. human. [Q15735-3 ]

    Organism-specific databases

    CTDi 27124.
    GeneCardsi GC22P031518.
    HGNCi HGNC:8956. INPP5J.
    HPAi HPA034539.
    MIMi 606481. gene.
    neXtProti NX_Q15735.
    PharmGKBi PA164720918.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG5411.
    HOGENOMi HOG000046051.
    HOVERGENi HBG082135.
    InParanoidi Q15735.
    KOi K01106.
    OMAi NIYQVTF.
    OrthoDBi EOG789CB4.
    PhylomeDBi Q15735.
    TreeFami TF317034.

    Enzyme and pathway databases

    BioCyci MetaCyc:HS11950-MONOMER.
    Reactomei REACT_121025. Synthesis of PIPs at the plasma membrane.
    REACT_150312. Synthesis of IP3 and IP4 in the cytosol.
    REACT_150352. Synthesis of IP2, IP, and Ins in the cytosol.

    Miscellaneous databases

    GeneWikii PIB5PA.
    GenomeRNAii 27124.
    NextBioi 49824.
    PROi Q15735.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q15735.
    Bgeei Q15735.
    CleanExi HS_INPP5J.
    Genevestigatori Q15735.

    Family and domain databases

    Gene3Di 3.60.10.10. 1 hit.
    InterProi IPR005135. Endo/exonuclease/phosphatase.
    IPR000300. IPPc.
    [Graphical view ]
    Pfami PF03372. Exo_endo_phos. 1 hit.
    [Graphical view ]
    SMARTi SM00128. IPPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56219. SSF56219. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
      Tissue: Cerebellum, Heart and Spleen.
    2. "The DNA sequence of human chromosome 22."
      Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M.
      , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H.
      Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (ISOFORM 1).
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    5. Nussbaum R.L.
      Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 610-1006.
      Tissue: Brain.

    Entry informationi

    Entry nameiPI5PA_HUMAN
    AccessioniPrimary (citable) accession number: Q15735
    Secondary accession number(s): B3KS54
    , Q32M61, Q6ZTH6, Q8N902, Q9UDT9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 30, 2003
    Last sequence update: October 17, 2006
    Last modified: October 1, 2014
    This is version 127 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 22
      Human chromosome 22: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3