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Q15562

- TEAD2_HUMAN

UniProt

Q15562 - TEAD2_HUMAN

Protein

Transcriptional enhancer factor TEF-4

Gene

TEAD2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
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    • History
      Entry version 129 (01 Oct 2014)
      Sequence version 2 (27 May 2002)
      Previous versions | rss
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    Functioni

    Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.2 Publications

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi40 – 10768TEAPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: Ensembl
    2. protein binding Source: UniProtKB
    3. RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Source: Ensembl
    4. sequence-specific DNA binding transcription factor activity Source: UniProtKB

    GO - Biological processi

    1. embryonic heart tube morphogenesis Source: Ensembl
    2. gene expression Source: Reactome
    3. hippo signaling Source: InterPro
    4. lateral mesoderm development Source: Ensembl
    5. negative regulation of cell death Source: Ensembl
    6. neural tube closure Source: Ensembl
    7. notochord development Source: Ensembl
    8. paraxial mesoderm development Source: Ensembl
    9. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
    10. regulation of transcription, DNA-templated Source: UniProtKB
    11. transcription initiation from RNA polymerase II promoter Source: Reactome
    12. vasculogenesis Source: Ensembl

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    ReactomeiREACT_116145. PPARA activates gene expression.
    REACT_118713. YAP1- and WWTR1 (TAZ)-stimulated gene expression.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transcriptional enhancer factor TEF-4
    Alternative name(s):
    TEA domain family member 2
    Short name:
    TEAD-2
    Gene namesi
    Name:TEAD2
    Synonyms:TEF4
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 19

    Organism-specific databases

    HGNCiHGNC:11715. TEAD2.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleoplasm Source: Reactome
    2. nucleus Source: InterPro
    3. transcription factor complex Source: Ensembl

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA36433.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 447447Transcriptional enhancer factor TEF-4PRO_0000205932Add
    BLAST

    Proteomic databases

    MaxQBiQ15562.
    PaxDbiQ15562.
    PRIDEiQ15562.

    PTM databases

    PhosphoSiteiQ15562.

    Expressioni

    Gene expression databases

    ArrayExpressiQ15562.
    BgeeiQ15562.
    CleanExiHS_TEAD2.
    GenevestigatoriQ15562.

    Interactioni

    Subunit structurei

    Interacts with YAP1 and WWTR1/TAZ.2 Publications

    Protein-protein interaction databases

    BioGridi114041. 6 interactions.
    DIPiDIP-59318N.
    IntActiQ15562. 2 interactions.
    STRINGi9606.ENSP00000310701.

    Structurei

    Secondary structure

    1
    447
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi229 – 23810
    Beta strandi249 – 2557
    Beta strandi268 – 2703
    Helixi271 – 2777
    Helixi285 – 2917
    Helixi294 – 2963
    Beta strandi297 – 3048
    Beta strandi326 – 33712
    Beta strandi340 – 34910
    Beta strandi352 – 36211
    Beta strandi364 – 3663
    Beta strandi369 – 37810
    Helixi381 – 39010
    Helixi396 – 4038
    Beta strandi406 – 4149
    Turni415 – 4173
    Beta strandi420 – 43011
    Beta strandi433 – 4353
    Beta strandi438 – 4458

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3L15X-ray2.00A/B217-447[»]
    ProteinModelPortaliQ15562.
    SMRiQ15562. Positions 40-115, 221-446.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ15562.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni172 – 447276Transcriptional activationSequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi152 – 21665Pro-richAdd
    BLAST

    Sequence similaritiesi

    Contains 1 TEA DNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG246992.
    HOVERGENiHBG056905.
    InParanoidiQ15562.
    KOiK09448.
    OrthoDBiEOG7288RP.
    PhylomeDBiQ15562.
    TreeFamiTF313443.

    Family and domain databases

    InterProiIPR000818. TEA/ATTS.
    IPR016361. TEF.
    [Graphical view]
    PANTHERiPTHR11834. PTHR11834. 1 hit.
    PfamiPF01285. TEA. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002603. TEF. 1 hit.
    PRINTSiPR00065. TEADOMAIN.
    SMARTiSM00426. TEA. 1 hit.
    [Graphical view]
    PROSITEiPS00554. TEA_1. 1 hit.
    PS51088. TEA_2. 1 hit.
    [Graphical view]

    Sequences (4)i

    Sequence statusi: Complete.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q15562-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MGEPRAGAAL DDGSGWTGSE EGSEEGTGGS EGAGGDGGPD AEGVWSPDIE    50
    QSFQEALAIY PPCGRRKIIL SDEGKMYGRN ELIARYIKLR TGKTRTRKQV 100
    SSHIQVLARR KSREIQSKLK DQVSKDKAFQ TMATMSSAQL ISAPSLQAKL 150
    GPTGPQASEL FQFWSGGSGP PWNVPDVKPF SQTPFTLSLT PPSTDLPGYE 200
    PPQALSPLPP PTPSPPAWQA RGLGTARLQL VEFSAFVEPP DAVDSYQRHL 250
    FVHISQHCPS PGAPPLESVD VRQIYDKFPE KKGGLRELYD RGPPHAFFLV 300
    KFWADLNWGP SGEEAGAGGS ISSGGFYGVS SQYESLEHMT LTCSSKVCSF 350
    GKQVVEKVET ERAQLEDGRF VYRLLRSPMC EYLVNFLHKL RQLPERYMMN 400
    SVLENFTILQ VVTNRDTQEL LLCTAYVFEV STSERGAQHH IYRLVRD 447
    Length:447
    Mass (Da):49,243
    Last modified:May 27, 2002 - v2
    Checksum:iA9077F55638A3AC7
    GO
    Isoform 2 (identifier: Q15562-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         155-155: P → PQVV

    Show »
    Length:450
    Mass (Da):49,569
    Checksum:iF90CF8D5E42E20E6
    GO
    Isoform 3 (identifier: Q15562-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-131: Missing.
         155-155: P → PQVV

    Show »
    Length:319
    Mass (Da):35,403
    Checksum:i91BCE65CE4E8A7D1
    GO
    Isoform 4 (identifier: Q15562-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         120-120: K → KALNV

    Note: No experimental confirmation available.

    Show »
    Length:451
    Mass (Da):49,640
    Checksum:i8DB857BAE7F47CF3
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti144 – 1441P → L in CAA64214. (PubMed:8702974)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 131131Missing in isoform 3. 2 PublicationsVSP_045126Add
    BLAST
    Alternative sequencei120 – 1201K → KALNV in isoform 4. CuratedVSP_055673
    Alternative sequencei155 – 1551P → PQVV in isoform 2 and isoform 3. 2 PublicationsVSP_045127

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK093236 mRNA. Translation: BAC04104.1.
    AK290736 mRNA. Translation: BAF83425.1.
    AK300241 mRNA. Translation: BAG62008.1.
    AC010524 Genomic DNA. No translation available.
    CH471177 Genomic DNA. Translation: EAW52469.1.
    BC051301 mRNA. Translation: AAH51301.1.
    BC007556 mRNA. Translation: AAH07556.1.
    BC018803 mRNA. No translation available.
    X94440 mRNA. Translation: CAA64214.1.
    CCDSiCCDS12761.1. [Q15562-1]
    CCDS58670.1. [Q15562-3]
    CCDS58671.1. [Q15562-2]
    PIRiG01116.
    RefSeqiNP_001243587.1. NM_001256658.1. [Q15562-2]
    NP_001243588.1. NM_001256659.1. [Q15562-2]
    NP_001243589.1. NM_001256660.1.
    NP_001243590.1. NM_001256661.1.
    NP_001243591.1. NM_001256662.1. [Q15562-3]
    NP_003589.1. NM_003598.1. [Q15562-1]
    XP_006723489.1. XM_006723426.1. [Q15562-1]
    UniGeneiHs.515534.

    Genome annotation databases

    EnsembliENST00000311227; ENSP00000310701; ENSG00000074219. [Q15562-1]
    ENST00000377214; ENSP00000366419; ENSG00000074219. [Q15562-2]
    ENST00000539846; ENSP00000437928; ENSG00000074219. [Q15562-3]
    ENST00000593945; ENSP00000469640; ENSG00000074219. [Q15562-4]
    ENST00000598810; ENSP00000472109; ENSG00000074219. [Q15562-4]
    ENST00000601519; ENSP00000469672; ENSG00000074219. [Q15562-2]
    GeneIDi8463.
    KEGGihsa:8463.
    UCSCiuc002png.4. human.
    uc002pnh.4. human. [Q15562-1]
    uc010yao.3. human.

    Polymorphism databases

    DMDMi21264529.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK093236 mRNA. Translation: BAC04104.1 .
    AK290736 mRNA. Translation: BAF83425.1 .
    AK300241 mRNA. Translation: BAG62008.1 .
    AC010524 Genomic DNA. No translation available.
    CH471177 Genomic DNA. Translation: EAW52469.1 .
    BC051301 mRNA. Translation: AAH51301.1 .
    BC007556 mRNA. Translation: AAH07556.1 .
    BC018803 mRNA. No translation available.
    X94440 mRNA. Translation: CAA64214.1 .
    CCDSi CCDS12761.1. [Q15562-1 ]
    CCDS58670.1. [Q15562-3 ]
    CCDS58671.1. [Q15562-2 ]
    PIRi G01116.
    RefSeqi NP_001243587.1. NM_001256658.1. [Q15562-2 ]
    NP_001243588.1. NM_001256659.1. [Q15562-2 ]
    NP_001243589.1. NM_001256660.1.
    NP_001243590.1. NM_001256661.1.
    NP_001243591.1. NM_001256662.1. [Q15562-3 ]
    NP_003589.1. NM_003598.1. [Q15562-1 ]
    XP_006723489.1. XM_006723426.1. [Q15562-1 ]
    UniGenei Hs.515534.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3L15 X-ray 2.00 A/B 217-447 [» ]
    ProteinModelPortali Q15562.
    SMRi Q15562. Positions 40-115, 221-446.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 114041. 6 interactions.
    DIPi DIP-59318N.
    IntActi Q15562. 2 interactions.
    STRINGi 9606.ENSP00000310701.

    PTM databases

    PhosphoSitei Q15562.

    Polymorphism databases

    DMDMi 21264529.

    Proteomic databases

    MaxQBi Q15562.
    PaxDbi Q15562.
    PRIDEi Q15562.

    Protocols and materials databases

    DNASUi 8463.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000311227 ; ENSP00000310701 ; ENSG00000074219 . [Q15562-1 ]
    ENST00000377214 ; ENSP00000366419 ; ENSG00000074219 . [Q15562-2 ]
    ENST00000539846 ; ENSP00000437928 ; ENSG00000074219 . [Q15562-3 ]
    ENST00000593945 ; ENSP00000469640 ; ENSG00000074219 . [Q15562-4 ]
    ENST00000598810 ; ENSP00000472109 ; ENSG00000074219 . [Q15562-4 ]
    ENST00000601519 ; ENSP00000469672 ; ENSG00000074219 . [Q15562-2 ]
    GeneIDi 8463.
    KEGGi hsa:8463.
    UCSCi uc002png.4. human.
    uc002pnh.4. human. [Q15562-1 ]
    uc010yao.3. human.

    Organism-specific databases

    CTDi 8463.
    GeneCardsi GC19M049843.
    HGNCi HGNC:11715. TEAD2.
    MIMi 601729. gene.
    neXtProti NX_Q15562.
    PharmGKBi PA36433.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG246992.
    HOVERGENi HBG056905.
    InParanoidi Q15562.
    KOi K09448.
    OrthoDBi EOG7288RP.
    PhylomeDBi Q15562.
    TreeFami TF313443.

    Enzyme and pathway databases

    Reactomei REACT_116145. PPARA activates gene expression.
    REACT_118713. YAP1- and WWTR1 (TAZ)-stimulated gene expression.

    Miscellaneous databases

    ChiTaRSi TEAD2. human.
    EvolutionaryTracei Q15562.
    GeneWikii TEAD2.
    GenomeRNAii 8463.
    NextBioi 31676.
    PROi Q15562.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q15562.
    Bgeei Q15562.
    CleanExi HS_TEAD2.
    Genevestigatori Q15562.

    Family and domain databases

    InterProi IPR000818. TEA/ATTS.
    IPR016361. TEF.
    [Graphical view ]
    PANTHERi PTHR11834. PTHR11834. 1 hit.
    Pfami PF01285. TEA. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002603. TEF. 1 hit.
    PRINTSi PR00065. TEADOMAIN.
    SMARTi SM00426. TEA. 1 hit.
    [Graphical view ]
    PROSITEi PS00554. TEA_1. 1 hit.
    PS51088. TEA_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
      Tissue: Placenta and Testis.
    2. "The DNA sequence and biology of human chromosome 19."
      Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S., Carrano A.V.
      , Caoile C., Chan Y.M., Christensen M., Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E., Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M., Rubin E.M., Lucas S.M.
      Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3).
      Tissue: Eye and Skin.
    5. "A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain."
      Jacquemin P., Hwang J.-J., Martial J.A., Dolle P., Davidson I.
      J. Biol. Chem. 271:21775-21785(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 32-367.
      Tissue: Brain.
    6. "TEAD mediates YAP-dependent gene induction and growth control."
      Zhao B., Ye X., Yu J., Li L., Li W., Li S., Yu J., Lin J.D., Wang C.Y., Chinnaiyan A.M., Lai Z.C., Guan K.L.
      Genes Dev. 22:1962-1971(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH YAP1.
    7. "TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition."
      Zhang H., Liu C.Y., Zha Z.Y., Zhao B., Yao J., Zhao S., Xiong Y., Lei Q.Y., Guan K.L.
      J. Biol. Chem. 284:13355-13362(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY, FUNCTION, INTERACTION WITH WWTR1.

    Entry informationi

    Entry nameiTEAD2_HUMAN
    AccessioniPrimary (citable) accession number: Q15562
    Secondary accession number(s): B4DTJ6
    , M0R1T9, Q8NA25, Q96IG3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: May 27, 2002
    Last modified: October 1, 2014
    This is version 129 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human chromosome 19
      Human chromosome 19: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3