Q15542 (TAF5_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Transcription initiation factor TFIID subunit 5

Alternative name(s):
Transcription initiation factor TFIID 100 kDa subunit
Short name=TAF(II)100
Short name=TAFII-100
Short name=TAFII100

Gene names

Name:	TAF5
Synonyms:	TAF2D

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	800 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. TAF5/TAFII100 interacts strongly with the histone H4-related TAF6/TAFII80 and the histone H3-related TAF9/TAFII31, as well as a stable complex comprised of both TAF5/TAFII80 and TAF6/TAFII31. Apparently weaker interactions of TAF5/TAFII100 with TBP, TAF1/TAFII250, TAF11/TAFII28, and TAF12/TAFII20, but not TAF7/TAFII55, also have been observed.
Subunit structure	TFIID and PCAF are composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TBP is not part of TFTC. Component of the TFTC-HAT complex, at least composed of TAF5L, TAF6L, TADA3L, SUPT3H/SPT3, TAF2/TAFII150, TAF4/TAFII135, TAF5/TAFII100, GCN5L2/GCN5, TAF10 and TRRAP. Interacts with SV40 Large T antigen. Ref.9 Ref.10 Ref.11
Subcellular location	Nucleus.
Domain	Distinct domains of TAF5/TAFII100 are required for functional interaction with transcription factor TFIIFB (RAP30) and incorporation into the TFIID complex.
Sequence similarities	Belongs to the WD repeat TAF5 family. Contains 1 LisH domain. Contains 6 WD repeats.
Sequence caution	The sequence AAC50902.1 differs from that shown. Reason: Erroneous initiation. The sequence BAD97335.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Host-virus interaction Transcription Transcription regulation
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Repeat WD repeat
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	histone acetylation Inferred from direct assay Ref.10. Source: GOC transcription elongation from RNA polymerase II promoter Traceable author statement. Source: Reactome transcription initiation from RNA polymerase II promoter Inferred from direct assay Ref.3PubMed 9603525. Source: UniProtKB viral reproduction Traceable author statement. Source: Reactome virus-host interaction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	actin cytoskeleton Inferred from direct assay. Source: HPA transcription factor TFIID complex Inferred from direct assay Ref.3. Source: UniProtKB transcription factor TFTC complex Inferred from direct assay Ref.10PubMed 9603525. Source: UniProtKB
Molecular_function	protein dimerization activity Inferred from direct assay PubMed 17227857. Source: UniProtKB sequence-specific DNA binding transcription factor activity Inferred from mutant phenotype Ref.3. Source: UniProtKB transcription regulatory region DNA binding Inferred from direct assay PubMed 17996705. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform Long (identifier: Q15542-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform Short (identifier: Q15542-2)

The sequence of this isoform differs from the canonical sequence as follows:
     556-610: Missing.

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 800

800

Transcription initiation factor TFIID subunit 5

PRO_0000051257

Regions

Domain

92 – 124

33

LisH

Repeat

468 – 507

40

WD 1

Repeat

541 – 580

40

WD 2

Repeat

583 – 624

42

WD 3

Repeat

625 – 666

42

WD 4

Repeat

667 – 706

40

WD 5

Repeat

709 – 748

40

WD 6

Compositional bias

46 – 49

4

Poly-Gly

Compositional bias

399 – 407

9

Poly-Lys

Natural variations

Alternative sequence

556 – 610

55

Missing in isoform Short.

VSP_006787

Natural variant

130

1

S → A. Ref.1 Ref.3 Ref.5 Ref.8
Corresponds to variant rs10883859 [ dbSNP | Ensembl ].

VAR_018462

Experimental info

Sequence conflict

126

1

A → T in CAA64777. Ref.1

Sequence conflict

126

1

A → T in BAD97335. Ref.5

Sequence conflict

300

1

F → L in CAA64777. Ref.1

Sequence conflict

455

1

P → S in CAA64777. Ref.1

Sequence conflict

469

1

A → V in CAA64777. Ref.1

Sequence conflict

778

1

Missing in CAA64777. Ref.1

Sequence conflict

787

1

R → L in AAH52268. Ref.8

Secondary structure

1

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

.

800

Helix Strand Turn

Details...

Helix

198 – 202

5

Helix

203 – 205

3

Helix

214 – 226

13

Helix

230 – 236

7

Helix

237 – 239

3

Helix

240 – 253

14

Helix

257 – 267

11

Helix

268 – 270

3

Helix

273 – 275

3

Helix

276 – 283

8

Helix

288 – 291

4

Helix

295 – 300

6

Helix

302 – 304

3

Beta strand

305 – 310

6

Helix

311 – 321

11

Helix

328 – 335

8

Beta strand

338 – 342

5

Sequences

	Sequence		Length	Mass (Da)
	Isoform Long [UniParc]. Last modified May 10, 2005. Version 3. Checksum: 87A178BFB7071992	FASTA	800	86,830
	10 20 30 40 50 60 MAALAEEQTE VAVKLEPEGP PTLLPPQAGD GAGEGSGGTT NNGPNGGGGN VAASSSTGGD 70 80 90 100 110 120 GGTPKPTVAV SAAAPAGAAP VPAAAPDAGA PHDRQTLLAV LQFLRQSKLR EAEEALRREA 130 140 150 160 170 180 GLLEEAVAGS GAPGEVDSAG AEVTSALLSR VTASAPGPAA PDPPGTGASG ATVVSGSASG 190 200 210 220 230 240 PAAPGKVGSV AVEDQPDVSA VLSAYNQQGD PTMYEEYYSG LKHFIECSLD CHRAELSQLF 250 260 270 280 290 300 YPLFVHMYLE LVYNQHENEA KSFFEKFHGD QECYYQDDLR VLSSLTKKEH MKGNETMLDF 310 320 330 340 350 360 RTSKFVLRIS RDSYQLLKRH LQEKQNNQIW NIVQEHLYID IFDGMPRSKQ QIDAMVGSLA 370 380 390 400 410 420 GEAKREANKS KVFFGLLKEP EIEVPLDDED EEGENEEGKP KKKKPKKDSI GSKSKKQDPN 430 440 450 460 470 480 APPQNRIPLP ELKDSDKLDK IMNMKETTKR VRLGPDCLPS ICFYTFLNAY QGLTAVDVTD 490 500 510 520 530 540 DSSLIAGGFA DSTVRVWSVT PKKLRSVKQA SDLSLIDKES DDVLERIMDE KTASELKILY 550 560 570 580 590 600 GHSGPVYGAS FSPDRNYLLS SSEDGTVRLW SLQTFTCLVG YKGHNYPVWD TQFSPYGYYF 610 620 630 640 650 660 VSGGHDRVAR LWATDHYQPL RIFAGHLADV NCTRFHPNSN YVATGSADRT VRLWDVLNGN 670 680 690 700 710 720 CVRIFTGHKG PIHSLTFSPN GRFLATGATD GRVLLWDIGH GLMVGELKGH TDTVCSLRFS 730 740 750 760 770 780 RDGEILASGS MDNTVRLWDA IKAFEDLETD DFTTATGHIN LPENSQELLL GTYMTKSTPV 790 800 VHLHFTRRNL VLAAGAYSPQ
	Isoform Short [UniParc]. Checksum: E97ADB7163F99617	FASTA	745	80,508
	10 20 30 40 50 60 MAALAEEQTE VAVKLEPEGP PTLLPPQAGD GAGEGSGGTT NNGPNGGGGN VAASSSTGGD 70 80 90 100 110 120 GGTPKPTVAV SAAAPAGAAP VPAAAPDAGA PHDRQTLLAV LQFLRQSKLR EAEEALRREA 130 140 150 160 170 180 GLLEEAVAGS GAPGEVDSAG AEVTSALLSR VTASAPGPAA PDPPGTGASG ATVVSGSASG 190 200 210 220 230 240 PAAPGKVGSV AVEDQPDVSA VLSAYNQQGD PTMYEEYYSG LKHFIECSLD CHRAELSQLF 250 260 270 280 290 300 YPLFVHMYLE LVYNQHENEA KSFFEKFHGD QECYYQDDLR VLSSLTKKEH MKGNETMLDF 310 320 330 340 350 360 RTSKFVLRIS RDSYQLLKRH LQEKQNNQIW NIVQEHLYID IFDGMPRSKQ QIDAMVGSLA 370 380 390 400 410 420 GEAKREANKS KVFFGLLKEP EIEVPLDDED EEGENEEGKP KKKKPKKDSI GSKSKKQDPN 430 440 450 460 470 480 APPQNRIPLP ELKDSDKLDK IMNMKETTKR VRLGPDCLPS ICFYTFLNAY QGLTAVDVTD 490 500 510 520 530 540 DSSLIAGGFA DSTVRVWSVT PKKLRSVKQA SDLSLIDKES DDVLERIMDE KTASELKILY 550 560 570 580 590 600 GHSGPVYGAS FSPDRLWATD HYQPLRIFAG HLADVNCTRF HPNSNYVATG SADRTVRLWD 610 620 630 640 650 660 VLNGNCVRIF TGHKGPIHSL TFSPNGRFLA TGATDGRVLL WDIGHGLMVG ELKGHTDTVC 670 680 690 700 710 720 SLRFSRDGEI LASGSMDNTV RLWDAIKAFE DLETDDFTTA TGHINLPENS QELLLGTYMT 730 740 KSTPVVHLHF TRRNLVLAAG AYSPQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Distinct domains of hTAFII100 are required for functional interaction with transcription factor TFIIF beta (RAP30) and incorporation into the TFIID complex." Dubrovskaya V., Lavigne A.-C., Davidson I., Acker J., Staub A., Tora L. EMBO J. 15:3702-3712(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG), VARIANT ALA-130. Tissue: Cervix carcinoma.
[2]	"Molecular cloning and analysis of two subunits of the human TFIID complex: hTAFII130 and hTAFII100." Tanese N., Saluja D., Vassallo M.F., Chen J.-L., Admon A. Proc. Natl. Acad. Sci. U.S.A. 93:13611-13616(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG), PROTEIN SEQUENCE OF 109-117; 119-142; 151-174; 372-388; 611-621; 635-649 AND 737-742, ALTERNATIVE SPLICING. Tissue: Cervix carcinoma.
[3]	"Specific interactions and potential functions of human TAFII100." Tao Y., Guermah M., Martinez E., Oegelschlaeger T., Hasegawa S., Takada R., Yamamoto T., Horikoshi M., Roeder R.G. J. Biol. Chem. 272:6714-6721(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LONG), VARIANT ALA-130. Tissue: Cervix carcinoma.
[4]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LONG).
[5]	Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LONG), VARIANT ALA-130. Tissue: Brain.
[6]	"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[8]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS LONG AND SHORT), VARIANT ALA-130. Tissue: Prostate and Testis.
[9]	"TAF-like function of SV40 large T antigen." Damania B., Alwine J.C. Genes Dev. 10:1369-1381(1996) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH SV40 LARGE T ANTIGEN.
[10]	"Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction." Brand M., Yamamoto K., Staub A., Tora L. J. Biol. Chem. 274:18285-18289(1999) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION IN THE TFTC-HAT COMPLEX WITH TAF5L; TAF6L; TADA3L; SUPT3H; TAF2; TAF4; TRRAP; GCN5L2 AND TAF10.
[11]	"Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis." Cavusoglu N., Brand M., Tora L., van Dorsselaer A. Proteomics 3:217-223(2003) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION IN THE TFTC-HAT COMPLEX, MASS SPECTROMETRY.
[12]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

X95525 mRNA. Translation: CAA64777.1.
U75309 mRNA. Translation: AAC50902.1. Different initiation.
U80191 mRNA. Translation: AAC51215.1.
AK223615 mRNA. Translation: BAD97335.1. Different initiation.
AK291229 mRNA. Translation: BAF83918.1.
AL591408 Genomic DNA. Translation: CAI16747.1.
CH471066 Genomic DNA. Translation: EAW49645.1.
CH471066 Genomic DNA. Translation: EAW49646.1.
BC052268 mRNA. Translation: AAH52268.2.
BC136340 mRNA. Translation: AAI36341.1.
BC136348 mRNA. Translation: AAI36349.1.

IPI

IPI00298925.
IPI00298926.

RefSeq

NP_008882.2. NM_006951.3.

UniGene

Hs.96103.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2NXP	X-ray	2.17	A/B/C/D/E/F/G/H	188-343	[»]

ProteinModelPortal

Q15542.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-28150N.

IntAct

Q15542. 5 interactions.

STRING

9606.ENSP00000358854.

PTM databases

PhosphoSite

Q15542.

Polymorphism databases

DMDM

78103206.

Proteomic databases

PaxDb

Q15542.

PRIDE

Q15542.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

Ensembl

ENST00000351396; ENSP00000311024; ENSG00000148835.
ENST00000369839; ENSP00000358854; ENSG00000148835.

GeneID

6877.

KEGG

hsa:6877.

UCSC

uc001kwv.3. human.
uc010qqq.2. human.

Organism-specific databases

CTD

6877.

GeneCards

GC10P105117.

HGNC

HGNC:11539. TAF5.

HPA

HPA006195.
HPA006474.

MIM

601787. gene.

neXtProt

NX_Q15542.

PharmGKB

PA36314.

GenAtlas

Search...

Phylogenomic databases

eggNOG

COG2319.

HOVERGEN

HBG050226.

InParanoid

Q15542.

KO

K03130.

OMA

ERQNNQI.

OrthoDB

EOG469QW7.

PhylomeDB

Q15542.

Enzyme and pathway databases

Reactome

REACT_116125. Disease.
REACT_1788. Transcription.
REACT_71. Gene Expression.

Gene expression databases

Bgee

Q15542.

CleanEx

HS_TAF5.

Genevestigator

Q15542.

GermOnline

ENSG00000148835. Homo sapiens.

Family and domain databases

Gene3D

2.130.10.10. 1 hit.

InterPro

IPR020472. G-protein_beta_WD-40_rep.
IPR006594. LisH_dimerisation.
IPR007582. TFIID-su_WD40-assoc_reg.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]

Pfam

PF04494. TFIID_90kDa. 1 hit.
PF00400. WD40. 6 hits.
[Graphical view]

PRINTS

PR00320. GPROTEINBRPT.

SMART

SM00667. LisH. 1 hit.
SM00320. WD40. 6 hits.
[Graphical view]

SUPFAM

SSF50978. WD40_like. 1 hit.

PROSITE

PS50896. LISH. 1 hit.
PS00678. WD_REPEATS_1. 3 hits.
PS50082. WD_REPEATS_2. 6 hits.
PS50294. WD_REPEATS_REGION. 2 hits.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q15542.

GenomeRNAi

6877.

NextBio

26855.

SOURCE

Search...

Entry information

Entry name

TAF5_HUMAN

Accession

Primary (citable) accession number: Q15542
Secondary accession number(s): A8K5B4 , B2RMR0, B7ZKJ6, Q53EM4, Q5SYD5, Q86UZ7, Q9Y4K5

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	May 10, 2005
Last modified:	May 1, 2013
This is version 134 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.