UniProtKB - Q15527 (SURF2_HUMAN)
(max 400 entries)x
Your basket is currently empty. i
Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)
Protein
Surfeit locus protein 2
Gene
SURF2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Surfeit locus protein 2Short name: Surf-2 |
Gene namesi | Name:SURF2 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000148291.9. |
HGNCi | HGNC:11475. SURF2. |
MIMi | 185630. gene. |
neXtProti | NX_Q15527. |
Subcellular locationi
Pathology & Biotechi
Organism-specific databases
PharmGKBi | PA36260. |
Polymorphism and mutation databases
DMDMi | 317373505. |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000072319 | 1 – 256 | Surfeit locus protein 2Add BLAST | 256 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 190 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 195 | PhosphothreonineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q15527. |
MaxQBi | Q15527. |
PaxDbi | Q15527. |
PeptideAtlasi | Q15527. |
PRIDEi | Q15527. |
PTM databases
iPTMneti | Q15527. |
PhosphoSitePlusi | Q15527. |
Expressioni
Gene expression databases
Bgeei | ENSG00000148291. |
CleanExi | HS_SURF2. |
Genevisiblei | Q15527. HS. |
Organism-specific databases
HPAi | HPA044340. HPA052213. |
Interactioni
Protein-protein interaction databases
BioGridi | 112702. 58 interactors. |
IntActi | Q15527. 7 interactors. |
MINTi | Q15527. |
STRINGi | 9606.ENSP00000361032. |
Structurei
3D structure databases
ProteinModelPortali | Q15527. |
SMRi | Q15527. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the SURF2 family.Curated
Phylogenomic databases
eggNOGi | ENOG410IK6I. Eukaryota. ENOG4111NE1. LUCA. |
HOGENOMi | HOG000136540. |
HOVERGENi | HBG054804. |
InParanoidi | Q15527. |
OrthoDBi | EOG091G0L5E. |
PhylomeDBi | Q15527. |
TreeFami | TF329107. |
Family and domain databases
InterProi | View protein in InterPro IPR008833. Surf2. |
Pfami | View protein in Pfam PF05477. SURF2. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q15527-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSELPGDVRA FLREHPSLRL QTDARKVRCI LTGHELPCRL PELQVYTRGK
60 70 80 90 100
KYQRLVRASP AFDYAEFEPH IVPSTKNPHQ LFCKLTLRHI NKCPEHVLRH
110 120 130 140 150
TQGRRYQRAL CKYEECQKQG VEYVPACLVH RRRRREDQMD GDGPRPREAF
160 170 180 190 200
WEPTSSDEGG AASDDSMTDL YPPELFTRKD LGSTEDGDGT DDFLTDKEDE
210 220 230 240 250
KAKPPREKAT DESRRETTVY RGLVQKRGKK QLGSLKKKFK SHHRKPKSFS
SCKQPG
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 24 | A → T in CAA84477 (PubMed:7702754).Curated | 1 | |
Sequence conflicti | 37 | P → T in CAA84477 (PubMed:7702754).Curated | 1 | |
Sequence conflicti | 142 – 143 | DG → EA in CAA84477 (PubMed:7702754).Curated | 2 | |
Sequence conflicti | 160 | G → A in CAA84477 (PubMed:7702754).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_014785 | 213 | S → G2 PublicationsCorresponds to variant dbSNP:rs12763Ensembl. | 1 | |
Natural variantiVAR_057001 | 221 | R → Q1 PublicationCorresponds to variant dbSNP:rs7863933Ensembl. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z35094 mRNA. Translation: CAA84477.1. CR456753 mRNA. Translation: CAG33034.1. AL158826 Genomic DNA. Translation: CAI12838.1. BC014411 mRNA. Translation: AAH14411.1. |
CCDSi | CCDS6967.1. |
PIRi | S57747. |
RefSeqi | NP_001265857.1. NM_001278928.1. NP_059973.4. NM_017503.4. |
UniGenei | Hs.159448. |
Genome annotation databases
Ensembli | ENST00000371964; ENSP00000361032; ENSG00000148291. |
GeneIDi | 6835. |
KEGGi | hsa:6835. |
UCSCi | uc004cdi.4. human. |
Keywords - Coding sequence diversityi
PolymorphismSimilar proteinsi
Entry informationi
Entry namei | SURF2_HUMAN | |
Accessioni | Q15527Primary (citable) accession number: Q15527 Secondary accession number(s): Q6IBP9, Q96CD1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | January 11, 2011 | |
Last modified: | February 28, 2018 | |
This is version 130 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |